Journal List > Asian Oncol Nurs > v.19(2) > 1129324

Asian Oncol Nurs. 2019 Jun;19(2):81-89. Korean.
Published online Jun 30, 2019.  https://doi.org/10.5388/aon.2019.19.2.81
© 2019 Korean Oncology Nursing Society
The Experience of Chemotherapy-induced Peripheral Neuropathy in People with Cancer
Pok Ja Oh,1 Eun Sook Choi,2 and Jin Lee3
1Department of Nursing, Sahmyook University, Seoul, Korea.
2National Cancer Center, Seoul, Korea.
3Department of Nursing, Graduate School, Sahmyook University, Seoul, Korea.

Address reprint requests to: Oh, Pok Ja. Professor, Department of Nursing, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul 01795, Korea. Tel: +82-2-3399-1589, Fax: +82-2-3399-1594, Email: ohpj@syu.ac.kr
Received Feb 13, 2019; Revised Apr 19, 2019; Accepted Apr 30, 2019.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nd/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

Purpose

The purpose of this study was to explore the experiences of adult cancer patients living with chemotherapy induced peripheral neuropathy (CIPN).

Methods

Data were collected from January 2018 to April 2018 through in-depth interviews with nine patients of colorectal and breast cancer. The main question was, ‘What is your experience living with CIPN such as tingling and/or numbness?’. The data were analyzed using Colaizzi's phenomenological method.

Results

Three theme clusters and six themes emerged: (1) unusual body change; ‘experience of unusual distressing symptoms’, ‘daily activities and functioning affected’, (2) CIPN: a less important risk; ‘CIPN: a distressing and have to endure’, ‘lack of concern and therapeutic communication’, (3) struggle for distressing CIPN through trial and error; ‘try all the remedies that can do’, ‘getting used to distressing CIPN’.

Conclusion

These results showed that patients did not consider CIPN important until symptoms affected daily activities and QOL. They then tried self-management strategies to deal with CIPN through trial and error. A two-way exchange of information between patients and health professionals could help patients understand CIPN and deal with symptoms if they occur.

Keywords: Chemotherapy; Peripheral neuropathy; Qualitative research

Tables


Table 1
Demographic and Disease-related Characteristics of the Participants
Click for larger image


Table 2
Theme Clusters and Themes on CIPN Experience
Click for larger image

Notes

This research was supported by the National Research Foundation of Korea (NRF) funded by the Korea government (MSIT) (No. NRF-2017RIA2B1002950).

References
1. Mols F, Beijers AJ, Vreugdenhil G, Verhulst A, Schep G, Husson O. Chemotherapy-induced peripheral neuropathy, physical activity and health-related quality of life among colorectal cancer survivors from the PROFILES registry. J Cancer Surviv 2015;9:512–522.
2. Trivedi MS, Hershman DL, Crew KD. Management of chemotherapy-induced peripheral neuropathy. Am J Hematol Oncol 2015;11:4–10.
3. Park SB, Goldstein D, Krishnan AV, Lin CS, Friedlander ML, Cassidy J, et al. Chemotherapy-induced peripheral neurotoxicity: a critical analysis. CA Cancer J Clin 2013;63:419–437.
4. Seretny M, Currie GL, Sena ES, Ramnarine S, Grant R, MacLeod MR, et al. Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis. Pain 2014;155:2461–2470.
5. Grenon NN, Chan J. Managing toxicities associated with colorectal cancer chemotherapy and targeted therapy: a new guide for nurses. Clin J Oncol Nurs 2009;13:285–296.
6. Velasco R, Bruna J, Briani C, Argyriou AA, Cavaletti G, Alberti P, et al. Early predictors of oxaliplatin-induced cumulative neuropathy in colorectal cancer patients. J Neurol Neurosurg Psychiatry 2014;85:392–398.
7. Drott JE, Starkhammar H, Börjeson S, Berterö CM. Oxaliplatin induced neurotoxicity among patients with colorectal cancer: documentation in medical records-a pilot study. Open J Nurs 2014;4:265–274.
8. Brami C, Bao T, Deng G. Natural products and complementary therapies for chemotherapy-induced peripheral neuropathy: a systematic review. Crit Rev Oncol Hematol 2016;98:325–334.
9. Derksen TM, Bours MJ, Mols F, Weijenberg MP. Lifestyle-related factors in the self-management of chemotherapy-induced peripheral neuropathy in colorectal cancer: a systematic review. Evid Based Complement Alternat Med 2017;2017:7916031
10. Hershman DL, Lacchetti C, Dworkin RH, Lavoie Smith EM, Bleeker J, Cavaletti G, et al. Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol 2014;32:1941–1967.
11. Finlay L. Ambiguous encounters: a relational approach to phenomenological research. Indo-Pac J Phenomenol 2009;9:1–17.
12. Colaizzi PF. Psychological research as the phenomenologist views it. In: Valle RS, King M, editors. Existential-phenomenological alternatives for psychology. New York, NY: Oxford University Press; 1978.
13. Sandelowski M. The problem of rigor in qualitative research. ANS Adv Nurs Sci 1986;8:27–37.
14. Tanay MA, Armes J, Ream E. The experience of chemotherapy-induced peripheral neuropathy in adult cancer patients: a qualitative thematic synthesis. Eur J Cancer Care (Engl) 2017;26:e12443
15. Tofthagen C, McAllister RD, McMillan SC. Peripheral neuropathy in patients with colorectal cancer receiving oxaliplatin. Clin J Oncol Nurs 2011;15:182–188.
16. Kim KY, Lee SH, Oh PJ. Chemotherapy-induced peripheral neuropathy and depression in cancer patients. Asian Oncol Nurs 2015;15:149–155.
17. Hwang WH. In: Assessment Using CIPNAT for Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy [dissertation]. Pusan: Kosin Univ.; 2013.
18. Attal N, Bouhassira D, Gautron M, Vaillant JN, Mitry E, Lepère C, et al. Thermal hyperalgesia as a marker of oxaliplatin neurotoxicity: a prospective quantified sensory assessment study. Pain 2009;144:245–252.
19. Kim JH, Choi KS, Kim TW, Hong YS. Quality of life in colorectal cancer patients with chemotherapy-induced peripheral neuropathy. J Korean Oncol Nurs 2011;11:254–262.
20. Tofthagen C. Patient perceptions associated with chemotherapy-induced peripheral neuropathy. Clin J Oncol Nurs 2010;14:E22–E28.
21. Speck RM, DeMichele A, Farrar JT, Hennessy S, Mao JJ, Stineman MG, et al. Scope of symptoms and self-management strategies for chemotherapy-induced peripheral neuropathy in breast cancer patients. Support Care Cancer 2012;20:2433–2439.
22. Tofthagen C. Surviving chemotherapy for colon cancer and living with the consequences. J Palliat Med 2010;13:1389–1391.
23. Oh PJ, Kim YL. Effectiveness of non-pharmacologic interventions in chemotherapy induced peripheral neuropathy: a systematic review and meta-analysis. J Korean Acad Nurs 2018;48:123–142.
24. Bennett BK, Park SB, Lin CS, Friedlander ML, Kiernan MC, Goldstein D. Impact of oxaliplatin-induced neuropathy: a patient perspective. Support Care Cancer 2012;20:2959–2967.
TOOLS
ORCID iDs

Pok Ja Oh
https://orcid.org/0000-0002-5963-5516

Eun Sook Choi
https://orcid.org/0000-0003-2891-3322

Jin Lee
https://orcid.org/0000-0001-9251-9982

Similar articles

Characteristics and Quality of Life in Gynecologic Cancer Patients with Chemotherapy-induced Peripheral Neuropathy

Disturbance in ADL from Chemotherapy-induced Peripheral Neuropathy and Quality of Life in Cancer Patients: The Mediating Effect of Psychological Distress

Factors Influencing Peripheral Neuropathy of Cancer Patients Undergoing Chemotherapy

Characteristics and Quality of Life in Patients with Chemotherapy-Induced Peripheral Neuropathy

Symptom and Interference of Activities of Daily Living of Chemotherapy-Induced Peripheral Neuropathy in Patients Receiving Taxanes and Platinums