This study was undertaken to identify the relationship between the subjective symptoms and the psychosocial well-being status of VDT operators. The study subjects of this study were 89 female telephone operators in Korea Telecom. The mean age of study subjects was 37.7 (s.d.; 3.1), and 91% of them were the married and 9% were the single. The mean values of psychosocial well-being status by general characteristics were not statistically significant. Of the 89 operators, 98.9% felt musculoskeletal subjective symptoms in shoulder, 91.2% in neck, 89.9% in hand, 89.9% in lowback, 88.9% in arm, 87.8% in back, and 85.6% in leg, respectively. The mean scores of the psychosocial well-being status by three categories of subjective symptoms were significant in shoulder, neck, arm, hand, and leg, but were not significant in back and lowback. Correlations between the subjective symptoms and the psychosocial well-being status were significant in discomfort scale, leg, arm, neck, shoulder, lowback, and hand, but were not significant in back. Multiple regression analysis were used to determine whether the independent variables (age, discomfort, and subjective symptoms) contributed to explaining the psychosocial well-being status. Discomfort and the subjective symptoms in leg were a correlate of the psychosocial well-being status.