Journal List > Korean J Obstet Gynecol > v.54(2) > 1088251

Kim, Kim, Chang, Jun, Jeon, and Lee: Calcinosis circumscripta of the both salpinx: A case report


Calcinosis circumscripta is defined by calcification in soft tissues. Clinically, calcinosis circumscripta is described as firm, white dermal papules, plaques, or subcutaneous nodules found in various sites. They commonly ulcerate, extruding a chalky white material that is frequently identified as hydroxyapatite. Calcinosis circumscripta most commonly involves the hand and wrist of middle-aged woman. The etiology and pathogenesis of calcinosis circumscripta are unknown. We experienced a case of calcinosis circumscrpita of salpinx which was suspected ovarian tumor. Calcinosis circumscripta is extremely rare in gynecologic area. Here we report the case with review of literature.

Figures and Tables

Fig. 1
Ultrasound showing the low echogenic mass (7.6×4.4×3.8 cm) with 2 chamber cysts of left ovary.
Fig. 2
A laparoscopic view of cul-de-sac (A). Chalky white material of left salpinx (B) and nodular mass of right salpinx (C) were noted. Postoperative view of cul-de-sac (D).
Fig. 3
Histologic finding. Well-circumscribed calcified nodules (arrows) within the muscular layer of the salpinx were noted (H&E, ×10).


1. Stewart VL, Herling P, Dalinka MK. Calcification in soft tissues. JAMA. 1983. 250:78–81.
2. Dalinka MK, Melchior EL. Soft tissue calcifications in systemic disease. Bull N Y Acad Med. 1980. 56:539–563.
3. Rothstein JL, Welt S. Calcinosis universalis and calcinosis circumscripta in infancy and in childhood: 3 cases of calcinosis universalis, with review of literature. Am J Dis Child. 1936. 52:368–422.
4. Swanson WW, Forster WG, Iob V. Calcinosis circumscripta. Am J Dis Child. 1933. 45:590–593.
5. Cousins MA, Jones DB, Whyte MP, Monafo WW. Surgical management of calcinosis cutis universalis in systemic lupus erythematosus. Arthritis Rheum. 1997. 40:570–572.
6. Tafti AK, Hanna P, Bourque AC. Calcinosis circumscripta in the dog: a retrospective pathological study. J Vet Med A Physiol Pathol Clin Med. 2005. 52:13–17.
7. Wong AC, Asai M, Masuda K, Wada E, Matsunaga T, Akahoshi Y. Calcinosis circumscripta. A case report. J Bone Joint Surg Am. 1986. 68:297–299.
8. Gaetani SA, Casiglia M, Zorini P. Calcinosis circumscripta: report of a case. Eur J Radiol. 1990. 11:222–223.
9. Mendoza LE, Lavery LA, Adam RC. Calcinosis cutis circumscripta. A literature review and case report. J Am Podiatr Med Assoc. 1990. 80:97–99.
10. Black AS, Kanat IO. A review of soft tissue calcifications. J Foot Surg. 1985. 24:243–250.
11. Raimer SS, Archer ME, Jorizzo JL. Metastatic calcinosis cutis. Cutis. 1983. 32:463–465.
12. Smack D, Norton SA, Fitzpatrick JE. Proposal for a pathogenesis-based classification of tumoral calcinosis. Int J Dermatol. 1996. 35:265–271.
13. Olsen KM, Chew FS. Tumoral calcinosis: pearls, polemics, and alternative possibilities. Radiographics. 2006. 26:871–885.
14. Walsh JS, Fairley JA. Calcifying disorders of the skin. J Am Acad Dermatol. 1995. 33:693–706.
15. Bundin JA, Feldman J. Soft tissue calcifications in systemic lupus erythematosus. Am J Roentgenol Radium Ther Nucl Med. 1975. 124:358–364.
16. Caniggia A, Gennari C, Vattimo A, Runci F, Bombardieri S. Prostaglandin PGE2: a possible mechanism for bone destruction in calcinosis circumscripta. Calcif Tissue Res. 1978. 25:53–57.
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