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Journal List > Korean J Leg Med > v.38(4) > 1087951

Jun, Kim, and Park: Suicidal Death by Nicotine Poisoning

Abstract

Nicotine is a water-soluble alkaloid extracted from tobacco plants, and most frequently encountered in snuff, chewing tobacco, cigarettes, cigars and pipe tobacco or in a limited number of pesticides. Nicotine overdose or poisoning might be serious or fatal and lead to death; caused by cardiovascular arrest, respiratory muscle paralysis, and/or central respiratory failure due to its toxic effect. Suicide by nicotine ingestion has been rarely reported due to emetic response. We present a case of suicidal nicotine poisoning. A 56-year-old man was found dead and the postmortem examination revealed no injury or disease. We confirmed a high concentration of nicotine in the toxicological test. Through scene investigation, we determined this case as a suicidal nicotine poisoning.

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kjlm-38-167f1.tif
Fig. 1.
Gastric contents shows semi-digested food material mixed with brownish fluid.
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kjlm-38-167f2.tif
Fig. 2.
The esophageal mucosa showed mild coagulation necrosis, and pinkish mucosal change is also observed over the entire gastric mucosa.
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