Journal List > J Nutr Health > v.48(5) > 1081409

J Nutr Health. 2015 Oct;48(5):398-406. Korean.
Published online October 30, 2015.  https://doi.org/10.4163/jnh.2015.48.5.398
© 2015 The Korean Nutrition Society
Effect of different levels of xylooligosaccharide in sugar on glycemic index and blood glucose response in healthy adults
Hyekyoung Nam,1 Myungok Kyung,2 Sheungwoo Seo,2 Sangwon Jung,2 and Moon-Jeong Chang1
1Department of Food & Nutrition, Kookmin University, Seoul 02707, Korea.
2R&D Center, TS Corporation, Incheon 22300, Korea.

To whom correspondence should be addressed. Email: cmoon@kookmin.ac.kr
Received September 24, 2015; Revised October 07, 2015; Accepted October 12, 2015.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

Purpose

In the present study, we aimed to evaluate the effect of sucrose containing 2 different levels of xylooligosaccharide on the glycemic index (GI) and blood glucose response in healthy adults.

Methods

Healthy adults (4 male participants and 6 female participants, n = 10) were randomized to receive glucose, sucrose, sucrose containing 7% xylooligosaccharide active elements (Xylo 7), or sucrose containing 10% xylooligosaccharide active elements (Xylo 10). Each participant was administrated one of these materials once a week for 8 weeks and an oral glucose tolerance test was performed.

Results

We found a reduction in the glycemic response to sucrose that included xylooligosaccharide active elements (Xylo 7 and Xylo 10). The glycemic indices of sucrose, Xylo 7 and Xylo 10 were 68.9, 54.7, and 52.5, respectively. The GI values of Xylo 7 and Xylo 10 were similar to that of foods with low GI. The percentage reduction of GI value caused by sucrose containing xylooligosaccharide active elements was significantly different and dose-dependent as compared to that caused by sucrose alone (p < 0.05). The reduction in the glycemic response to Xylo 7 and Xylo 10 was 21% and 24%, respectively, as compared to the glycemic response to sucrose. The attenuation of the glycemic response to Xylo 10 tended to be higher than that for Xylo 7 when the percentage of body fat was increased.

Conclusion

These results demonstrated that xylooligosaccharide active elements may be effective in protecting humans against overconsumption of sucrose.

Keywords: xylooligosaccharide active element; blood glucose; glycemic index; healthy adults

Figures


Fig. 1
Mean blood glucose responses after administration of control food (glucose) and test food (sucrose, Xylo 7 and Xylo 10). Each value is the mean ± SD. Different alphabets at same time are significant (p < 0.05) between groups. Xylo 7: sucrose with 14% xylooligosaccaride powder (active element X2~X7 7%), Xylo 10: sucrose with 20% xylooligosaccaride powder (active element X2~X7 10%)
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Tables


Table 1
Test food composition in the clinical trial
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Table 2
Baseline characteristics of the subjects in the clinical trial (n = 10)
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Table 3
Glycemic indices of Xylo 7 and Xylo 10 (n = 10)
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Table 4
The changes in blood glucose variables (n = 10)
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Notes

This research was supported by High Value-added Food Technology Development Program (Project number: 313024-03-1-CG000), Ministry for Food, Agriculture, Forestry, Republic of Korea.

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