Abstract
Purpose
The objective of this study was to investigate the effects of xyloologosaccharide (XOS)-sugar mixture on glycemic index (GI) and blood glucose in human subjects.
Methods
Randomized double-blind cross-over studies were conducted to examine the effect of sucrose with 14% xyloologosaccharide powder (Xylo 14) and sucrose with 20% xylooligosaccharide powder (Xylo 20) on GI and postprandial glucose response at 15, 30, 45, 60, 90, and 120 min.
Results
GIs of Xylo 14 and Xylo 20 were 60.0 ± 23.5 classified within medium GI range, and 54.3 ± 17.7 within low GI range, respectively. Xylo 14 and Xylo 20 showed significantly lower area under the glucose curve (AUC) for 0-15 min (p = 0.0113), 0-30 min (p = 0.0004), 0-45 min (p < 0.0001), 0-60 min (p < 0.0001), 0-90 min (p < 0.0001), and 0-120 min (p = 0.0001). In particular, compared with glucose, the blood glucose levels of Xylo 14 and Xylo 20 were significantly lower at every time point between 15 and 120 min.
Figures and Tables
Fig. 1
Mean blood glucose responses after administration of control food (glucose) and test food (Xylo 14 and Xylo 20). Each value is the mean ± SD. Time points with a p-value indicate a significant difference between groups. Xylo 14, sucrose with 14% xylooligosaccharide powder; Xylo 20, sucrose with 20% xylooligosaccharide powder.
![jnh-47-229-g001](/upload/SynapseData/ArticleImage/1124jnh/jnh-47-229-g001.jpg)
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