Journal List > J Nutr Health > v.47(4) > 1081341

J Nutr Health. 2014 Aug;47(4):229-235. Korean.
Published online August 31, 2014.  https://doi.org/10.4163/jnh.2014.47.4.229
© 2014 The Korean Nutrition Society
Effects of xylooligosaccharide-sugar mixture on glycemic index (GI) and blood glucose response in healthy adults
Myungok Kyung,1,** HanSaem Choe,2,** Sangwon Jung,1 Kyungsun Lee,1 SungEun Jo,1 Sheungwoo Seo,1 Keunbum Choe,1 Chang-Kun Yang,3 Sang-Ho Yoo,4 and Yuri Kim2
1R&D Center, TS Corporation, Incheon 400-201, Korea.
2Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 120-750, Korea.
3TS Food & System, Seoul 135-921, Korea.
4Department of Food Science & Technology, BK21 Plus Team, and Carbohydrate Bioproduct Research Center, Sejong University, Seoul 143-747, Korea.

To whom correspondence should be addressed. tel: +82-2-3277-4485, Email: yuri.kim@ewha.ac.kr

**Equal contribution as the first author.

Received May 10, 2014; Revised June 10, 2014; Accepted August 01, 2014.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

Purpose

The objective of this study was to investigate the effects of xyloologosaccharide (XOS)-sugar mixture on glycemic index (GI) and blood glucose in human subjects.

Methods

Randomized double-blind cross-over studies were conducted to examine the effect of sucrose with 14% xyloologosaccharide powder (Xylo 14) and sucrose with 20% xylooligosaccharide powder (Xylo 20) on GI and postprandial glucose response at 15, 30, 45, 60, 90, and 120 min.

Results

GIs of Xylo 14 and Xylo 20 were 60.0 ± 23.5 classified within medium GI range, and 54.3 ± 17.7 within low GI range, respectively. Xylo 14 and Xylo 20 showed significantly lower area under the glucose curve (AUC) for 0-15 min (p = 0.0113), 0-30 min (p = 0.0004), 0-45 min (p < 0.0001), 0-60 min (p < 0.0001), 0-90 min (p < 0.0001), and 0-120 min (p = 0.0001). In particular, compared with glucose, the blood glucose levels of Xylo 14 and Xylo 20 were significantly lower at every time point between 15 and 120 min.

Conclusion

The results of this study suggested that Xylo 14 and Xylo 20 had an acute suppressive effect on GI and the postprandial glucose surge.

Keywords: xylooligosaccharide (XOS); sugar; GI (glycemic index); area under the curve (AUC); blood glucose

Figures


Fig. 1
Mean blood glucose responses after administration of control food (glucose) and test food (Xylo 14 and Xylo 20). Each value is the mean ± SD. Time points with a p-value indicate a significant difference between groups. Xylo 14, sucrose with 14% xylooligosaccharide powder; Xylo 20, sucrose with 20% xylooligosaccharide powder.
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Tables


Table 1
Test food compositions in the clinical trial
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Table 2
Baseline characteristics of the subjects in the clinical trial n = 11
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Table 3
Glycemic indices of Xylo 14 and Xylo 20 n = 11
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Table 4
Blood glucose areas under curve (AUC) in subjects after ingestion of Glucose, Xylo 14, and Xylo 20 n = 11
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Notes

This research was supported by High Value-added Food Technology Development Program (Project number: 313024-03-1-CG000), Mi-nistry for Food, Agriculture, Forestry and Fisheries, Republic of Korea.

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