Journal List > Infect Chemother > v.43(5) > 1035114

Nam, Hong, Hong, Lim, Kim, Jung, Song, and Ryu: A Case of Pseudomembranous Tracheobronchitis Complicated by Coinfection of 2009 Pandemic Influenza A/H1N1 and Staphylococcus aureus


An influenza pandemic due to a novel influenza A/H1N1 virus occurred after April 2009. This virus has some characteristics that differentiate it from the seasonal influenza virus. The 2009 pandemic influenza A/H1N1 virus can frequently infect the lower respiratory tract, and it might cause acute tracheobronchitis as well as pneumonia. Viral-bacterial interaction is well known as an important mechanism of the pathogenesis of respiratory complications of influenza. Herein, we report on a case that presented with pseudomembranous tracheobronchitis complicated by coinfection with 2009 pandemic influenza A/H1N1 and Staphylococcus aureus. We also review the relevent literature.

Figures and Tables

Figure 1
(A) The initial chest X-ray showed multiple nodular opacities in both lung fields. (B) The chest X-ray taken 6 days after admission showed progressed consolidation and patchy infiltration in both lung fields. (C) The follow-up chest X-ray after discharge showed that the multifocal pneumonic infiltrations had cleared up.
Figure 2
The initial chest CT showed multiple centrilobular opacities in both lungs, and diffuse bronchial thickening and narrowing of both bronchi.
Figure 3
(A), (B) The initial bronchoscopic findings showed severe mucosal inflammation and focal ulcerations with a pseudomembrane at the posterior membranous wall of the tracheobronchial tree. (C) A follow-up bronchoscopy 6 days later showed the much-improved mucosal inflammation and the disappearance of the pseudomembrane in the tracheobronchus.


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