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Ryoo, Cho, Choi, Park, Choi, Kim, Han, Kim, Jeon, and Khang: Functional MRI of Language: Difference of its Activated Areas and Lateralization according to the Input Modality
Original Article
Journal of the Korean Society of Magnetic Resonance in Medicine

Journal of the Korean Society of Magnetic Resonance in Medicine 2011; 15(2): 130-138.

Published online: 31 August 2011

DOI: https://doi.org/10.13104/jksmrm.2011.15.2.130

Functional MRI of Language: Difference of its Activated Areas and Lateralization according to the Input Modality

Jae Wook Ryoo2, Jae Min Cho1, Ho Chul Choi1, Mi Jung Park1, Hye-Young Choi1, Ji Eun Kim1, Heon Han3, Sam Soo Kim3, Yong Hwan Jeon3, Hyun-Soo Khang4

1Department of Radiology, Gyeongsang National University School of Medicine, Korea.

2Department of Radiology, Samsung Medical Center, Korea.

3Department of Radiology, Kangwon National University College of Medicine, Korea.

4Department of Radiology Technology, Eulji University College of Health Sciences, Korea.

Corresponding author: Jae Min Cho, M.D., Department of Radiology, Gyeongsang National University Hospital, 90 Chilam-dong, Jinju 660-702, Korea. Tel. 82-55-750-8211, Fax. 82-55-758-1568, jmcho@gnu.ac.kr

Received 29 June 2011       Revised 25 July 2011       Accepted 18 August 2011

Copyright © 2011 Korean Society of Magnetic Resonance in Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To compare fMRIs of visual and auditory word generation tasks, and to evaluate the difference of its activated areas and lateralization according to the mode of stimuli.

Materials and Methods

Eight male normal volunteers were included and all were right handed. Functional maps were obtained during auditory and visual word generation tasks in all. Normalized group analysis were performed in each task and the threshold for significance was set at p<0.05. Activated areas in each task were compared visually and statistically.

Results

In both tasks, left dominant activations were demonstrated and were more lateralized in visual task. Both frontal lobes (Broca's area, premotor area, and SMA) and left posterior middle temporal gyrus were activated in both tasks. Extensive bilateral temporal activations were noted in auditory task. Both occipital and parietal activations were demonstrated in visual task.

Conclusion

Modality independent areas could be interpreted as a core area of language function. Modality specific areas may be associated with processing of stimuli. Visual task induced more lateralized activation and could be a more useful in language study than auditory task.

Keywords: Brain, Magnetic resonance (MR), Functional, Language

Figures and Tables

Fig. 1
Diagram of fMRI acquisition.
jksmrm-15-130-g001
Fig. 2
Average activation maps of visual word generation task rendered on template brain (8 data were group). Left dominant activation is seen in the inferior frontal gyrus, premotor, supplementary motor areas, both angular gyri, and both occipital lobes. Temporal activation is demonstrated in the middle temporal gyrus.
jksmrm-15-130-g002
Fig. 3
Average activation maps of auditory word generation task rendered on template brain (8 data were group). Frontal activations are similar to those of the visual task (Fig. 2). Extensive temporal activations encompass superior, posterior middle and inferior temporal gyri are noted. Left dominance is less prominent than visual task.
jksmrm-15-130-g003
Fig. 4
Activation maps of task difference for the visual and auditory task. Red indicates significantly more activation in the visual task.
jksmrm-15-130-g004

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