The emergence of ethical concerns regarding the use of artificial intelligence (AI) dates back to the early days of its development. Most sources claim that the modern development of AI began in the early 1950s with the work of Alan Mathison Turing. He performed the “Turing test,” which showed that computers could think like humans. His paper “Computing Machinery and Intelligence” brought about debates about machine intelligence that would eventually lead to ethical considerations.1 The term “artificial intelligence” was first coined by John McCarthy at a conference in 1956.23 He has done outstanding research in the field of AI.2 With the advancement of computer technology, AI became more widely applied in the years of 1970 and 1980. This raised concerns about privacy and decision-making biases. In 1976, Joseph Weizenbaum’s book “Computer Power and Human Reason” addressed the moral responsibility of AI developers.4 In the 1990s, Dr. Richard Wallace created ALICE (Artificial Linguistic Internet Computer Entity), the first chatbot to interact with humans.5 Since the 1990s, ethical concerns in the use of AI have become more prominent and the need for ethical regulations and guidelines has been discussed by stakeholders.

What is the modern definition of AI? As pointed out by Chen J “The goal of AI is to build systems that can learn and adapt as they make well-informed decisions, that is, systems that have certain levels of autonomy (i.e., the capability of task and motion planning) as well as intelligence (i.e., the capability of decision-making and reasoning).”6 The current definition in Britannica is as follows; AI is “the ability of a digital computer or computer-controlled robot to perform tasks commonly associated with intelligent beings.”7 Many different AI applications are currently used in healthcare, such as robotics, image processing, big data analysis, machine learning, voice recognition, and predictive modeling.8

One of the most widely used AI tools in scientific publishing is the Chatbots, which can generate text, code, video/images, and full research articles. From information retrieval to data analysis and plagiarism detection, AI tools facilitate the work of not only researchers but also editors and publishers in many areas (Table 1).91011 However, we should be aware of not only the strengths but also the weaknesses or limitations of AI tools.1213 They lack consciousness. They lack creative or original ideas because they can only create content based on the libraries they were trained in. The information compiled by the chatbot may be inaccurate, out of date, and may contain subjective biases. They may even list references that do not exist. More worryingly, they can facilitate the production of fraudulent manuscripts such as paper mills.14

While the responsible use of AI brings many innovations and benefits for science and humanity, its unethical use, such as fabricated articles, poses a serious threat to scientific integrity and literature.151617 Even without malicious use, the chatbot output itself is at risk of containing biases, distortions, irrelevancies, misrepresentations, and plagiarism.1819 Therefore, the use of complex AI algorithms raises concerns about bias, transparency, and accountability, which calls for the development of new ethical guidelines to protect scientific integrity.

We are now witnessing AI technologies reshaping the field of academic publishing. As researchers, authors, reviewers, and editors, we are in a period where we all have to renew and improve our knowledge on this subject. We need to recognize the rapidly changing dynamics in scholarly publishing and address some concerns and challenges to ensure that AI tools and chatbots are used ethically and responsibly in academia. Some of these issues include the debate on how to disclose the use of AI in a manuscript, how to prevent the publication of fabricated manuscripts and the changing standards of retraction.

Go to :

The main purpose of this narrative review article is to inform readers, authors, reviewers, and editors about new approaches to publication ethics in the age of AI. It specifically focuses on how to disclose the use of AI in your writing, how to avoid publishing text entirely generated by AI, and tips on current standards for retraction.

Go to :

I have prepared a list of keyword combinations such as ‘Artificial Intelligence,’ ‘Ethics in Publishing,’ ‘Scientific Fraud,’ ‘Scientific Integrity,’ ‘Scientific Misconduct,’ ‘Research Misconduct,’ and ‘Retraction of Publication.’ I took the presence of Medical Subject Headings terms into account when choosing my search queries. I searched MEDLINE/PubMed, Scopus, Web of Science, and the Directory of Open Access Journals. I also checked the “similar articles section” for additional PubMed citations closely related to the articles listed with the initial ‘MeSH’ terms. Google Scholar search was conducted for some terms that have no equivalent in MeSH (e.g. chatbot, paper mills, fabricated manuscripts). I did not set any time limits or intervals when creating our search strategy. All article types were included in the searches. Publications that are not suitable for my purpose, not in English and not full text are excluded. I focused specifically on articles related to standards for disclosure of AI, avoiding the publication of fabricated manuscripts, and new and changing standards for retracting articles.

Go to :

Journals vary in their policies on the use of generative AI for scientific writing. Some publishers prohibit the use of AI without explicit editorial authorization,20 while others require detailed annotation in the manuscript.2122 In his article, Hosseini argues that banning these tools could encourage the undisclosed use of chatbots, which would undermine transparency and integrity in research.23 He also emphasized that it would undermine the principle of equality and diversity in science for non-native speakers of English.

WAME revised its recommendations on “Chatbots and Generative AI in Relation to Scientific Publication” in May 2023.18 These recommendations can be considered as general principles. The first version emphasizes transparency, honesty, and responsibility of authors. For the second version, the suggestion that editors and peer reviewers should inform authors and be transparent when using AI in the manuscript evaluation process was added (Table 2).

Where in your article and how do we disclose the use of AI in your manuscript? There is a bit more disagreement about where to disclose rather than how to disclose. Some journals require authors to detail the use of AI in the acknowledgments section,242526 while others prefer it to be described in the body of the text.2728 The logic behind the idea that it would not be appropriate to use it in the acknowledgments section is that they cannot be accepted as authors because they cannot take responsibility or accountability for the research.23 APA recommends disclosure in the methods section in research articles and the introduction section in other types of articles.28 If AI was used for data collection, analysis, or figure generation, ICMJE and COPE recommend describing its use in the methods section.

How do we disclose the use of AI? First of all, authors should read the journal AI policies before submission. Journals/Publishers expect you to be transparent and honest. You are asked to detail what you did and how you did it, and to indicate where the AI-generated content fits into your manuscript (Table 3). You must keep all your prompts and answers and most journals require you to declare them.

Another important issue is how to cite AI. Of course, the journal instructions should be read, but it is necessary to include information such as the version used, the model used, and the date of use. For example, the following format suggested by Hosseini seems informative enough23:

“OpenAI (2023). ChatGPT (GPT-4, 12 May Release) [Large language model]. Response to query X.Y. Month/Day/Year. https://chat.openai.com/chat”

Go to :

We all know that non-native English speakers face disadvantages in the primarily Anglophone publishing business and often have to send their work to expensive and time-consuming translation and editing agencies. AI tools like ChatGPT can play an important role in helping non-native English academics write and edit their papers. It also encourages researchers who shy away from peer review due to language difficulties to take on the role of reviewer. Therefore, AI tools, especially if freely available, can promote and improve scientific equity.29 The important thing here is that the author informs the journal and the publisher transparently.

On the other hand, AI tools can easily be used in an unethical way, resulting in misconduct and even fraud. AI tools can now produce full papers, which threatens the integrity of science. Paper mills are one of the final points of scientific fraud. This business began to emerge as a response to the publish-or-perish policy. Paper mills are heavily dependent on AI-generated texts that often contain fake or low-quality data.30 Authors pay to have their names appear in these papers. They try to bribe journal editors to get manuscripts accepted quickly. So, the need to distinguish human writing from AI is critical. AI tools can play an important role in detecting or suspecting this scientific misconduct/fraud.

Currently, AI tools such as PapermillAlarm, GPTZero, GPT-2 Output Detector, Profig, FigCheck, and ImaCheck are used by some publishers to detect fabricated papers and image manipulation.313233 However, journals and publishers should be aware of their limitations and that they are not infallible. They can produce false positive or false negative results, and many errors in images flagged by AI tools can result in false positive results.32 Gao et al.34 evaluated the abstracts generated by ChatGPT for 50 scientific medical articles. They collected titles and originals extracted abstracts from recent issues of five high-impact journals and compared them with the original abstracts. It was noted that only 68% of ChatGPT-generated abstracts and 86% of human-written abstracts were correctly identified. The effectiveness of AI text content detectors, such as OpenAI, Writer, Copyleaks, GPTZero, and CrossPlag, was the subject of another study.35 The study’s findings show that there is a wide range in the tools’ capacity to distinguish between text that is correctly identified as AI-generated or human-written. Overall, the tools perform better at classifying text that is GPT 3.5-generated than content that is GPT 4-generated or written by humans. In the preliminary study by Habibzadeh, a total of 50 text fragments were used to determine the performance of Gptzero in distinguishing machine-generated texts from human-written texts.36 It recorded an accuracy rate of 80% with positive and negative probabilities of 6.5 and 0.4, respectively. He concluded GPTZero had a low false-positive (classifying a human-written text as machine-generated) and a high false-negative rate (classifying a machine-generated text as human-written).

So, AI tools for discriminating from AI- from human-derived text is currently not good enough and need to enhance their accuracy and reliability.3537 They can also be easily bypassed by using an online rewording tool or by rewording it oneself.38 Therefore, suspected misconduct identified by AI tools should be carefully scrutinized by humans to confirm accuracy as suggested by COPE.39 As pointed out by Gasparyan, the advice of experienced editors on how the credibility of academic publications is threatened by blind reliance on online processing should not be ignored.40 Sometimes the best way to ensure that this is a legitimate manuscript is to ask the author to provide the raw data of the study.37

What makes the problem a little more complicated for us is that establishing strict rules on ethics in scientific publishing is not an easy task. In the age of AI, where do you draw the line between ethical and unethical behavior? More specifically, what should be the maximum percentage of AI content in an article? Is there a standard percentage set by journals for AI content? Unfortunately, editorial guidelines from global associations such as ICMJE, COPE and WAME generally outline the general framework for publishing ethics, but do not provide specific advice to authors and editors specifically on AI and ethics.40

Go to :

In 2013, Steen et al.41 conducted an important study showing that the reasons for retraction have expanded in recent years to include plagiarism and duplicate publication. One of the study’s conclusions was that lower barriers to retraction were apparent in an increase in retraction for “new” offenses such as plagiarism. Spanish group recently published two important trials. In the study by Candal-Pedreira et al., retracted articles originating from paper mills were evaluated. They reported that the ratio of paper mill retractions to all-cause retractions reached 21.8% (772/3,544) in 2021.42 In their second trial, retracted papers from European institutions between 2000 and 2021 were analyzed. They noted retraction rates increased from 10.7 to 44.8 per 100,000 publications between 2000 and 2020. Research misconduct was the reason in 2/3 of retractions. From copyright and authorship issues in 2000 (2.5 per 100,000 publications) to duplications in 2020 (8.6 per 100,000 publications), they disclosed causes for retractions that changed over time.43

In the recently published systematic review of studies of retraction notices, misconduct accounted for 60% of all retractions, confirming the results of the studies mentioned above.44 According to the claim by “Retraction Watch,” hundreds of IEEE publications produced in the previous years contained plagiarized material, citation fraud, and distorted wording.45 Voung et al.46 reported that manipulated peer review was the most common reason for retraction in the 2010s. By analyzing 18,603 retractions compiled from the Retraction Watch database until 2019, they reported that manipulated peer review was responsible for 676 retractions in the period 2012–2019. Hard-to-believe findings were presented in Van Noorden’s research, which was just published in Nature.47 A new annual record was set in 2023, with more than 10,000 retractions of research articles. The main reasons for this were the “paper mills” engaged in systematic manipulation of the peer review and publication processes. Even more worrying, integrity experts claimed this was just the “tip of the iceberg.” In 2015, WAME published an action plan to prevent “fake” reviewers from conducting reviews by searching for and verifying the ORCID IDs of potential reviewers in response to growing concerns about these activities worldwide.40 However, the most decisive point here will be the approach and uncompromising attitude of journal editors towards publication ethics and scientific integrity.

In non-Anglophone countries, plagiarism in particular stands out as a reason for retraction. Koçyiğit et al.48 drew attention to the increase in the number of retracted articles from Turkey in recent years and reported the most common reasons for retraction as plagiarism, duplication, and error. Gupta et al.49 conducted to analyze plagiarism perceptions among researchers and journal editors, particularly from non-Anglophone countries. This survey confirmed again that despite increased global awareness of plagiarism, non-Anglophone medical researchers do not understand the issue sufficiently. While most agree that copying text and images is plagiarism, other behaviors, such as stealing ideas and paraphrasing previously published work, are considered outside the scope of plagiarism. They conclude that closing the knowledge gap by providing up-to-date training and widespread use of advanced anti-plagiarism software can address this unmet need.

These studies have shown us the changing concepts and practices for retractions over the last decade. What was the driver behind this? The use of advanced technology in publishing helps us to detect plagiarism and duplication. On the other hand, the misuse of technology raises some ethical issues such as paper mills, image manipulation, confidentiality issues, and non-disclosure of competing interests. Such an unethical act not only compromises the integrity of publishing and science but may also require the retraction of the article.

The first version of the COPE retraction guideline was published in 2009. A revised version was published in 2019 to set the current standards (Table 4).50 As can be seen in Table 4, image manipulation, lack of authorization for material or data use, some legal issues, compromised peer review, and non-disclosure of conflict of interest were added as reasons for retraction. However, as Teixeria da Silva notes, the COPE, ICMJE, and CSE ethics guidelines are still incomplete in that they do not specifically address fake articles, authors, emails and affiliations associated with stings and hoaxes.51

Another popular topic in recent years is self-retraction. As many experts have emphasized, self-retraction due to honest errors deserves more credit than it currently receives. Fanelli argues that such publications should be viewed as legitimate publications that scholars will treat as evidence of integrity.52

Go to :

Currently, international organizations such as COPE, ICMJE, and CSE share the same views on authorship, AI disclose, transparency and responsibility, and ethical use of AI in their recommendations on AI use in scholarly publishing (Table 5). While acknowledging AI’s role in decision-making, COPE emphasizes the necessity of responsibility, transparency, and human oversight when incorporating AI tools into the peer review process. The ICMJE defines the use of AI in peer review but advocates restricting the use of AI by editors. The CSE recommendations are similar to those of ICJME and COPE but do not refer to reviewers and editors. As shown in the Table 2, WAME details how to disclose the use of AI for your article and recommends that editors should have these AI tools.

AI technology will undoubtedly develop and play a bigger role in day-to-day living. Therefore, these developments in AI will reshape scientific publishing and ethics. More scientists, reviewers, and editors will endeavor to be more transparent about their work as well as be more aware of the ethical issues surrounding the use of AI. Education on ethics and AI will become more important and researchers will have to consider ethical issues in their projects. Shortly, equity and unrestricted access to these technologies may emerge as the most significant issues in AI ethics, particularly for non-native English speakers. So, it will be crucial to have common regulations and the same ethical standards for all countries. Governments and funding organizations will have to develop policies to further support ethical research on AI. Perhaps in the near future, a new concept, empathic AI, as proposed by Kasani et al.53 could help protect research and publication ethics by overcoming the limitations of human empathy.

This narrative review has several restrictions. Excluding non-English articles could lead to bias. Another drawback was that some articles could not be accessed in full text, therefore they were excluded. It is also possible that publications in journals that are not listed in the indexes used for literature search may have been overlooked. These factors could affect the comprehensiveness and objectivity of the review.

Go to :

The application of new technologies to science affects the way and methodology in which research is conducted. Unfortunately, the development and writing of ethical codes cannot keep up with the pace of development and application of technology. Moreover, preparing guidelines is not an easy task because codes of ethics are not completely black and white. Therefore, the fight against scientific misconduct is multi-faceted, continuous, and requires teamwork.54 Table 3 is intended as a checklist for authors before writing and submitting an AI-assisted manuscript. I hope this review will guide authors, reviewers, and editors on the responsible use of AI and help raise awareness on this issue. Journals and publishers should have clear and transparent policies on the ethical use of AI for the drafting, editing, and reviewing of manuscripts. They should also avoid unfairly blaming authors when taking action against the unethical use of AI. Educating staff and editorial boards on this issue is not only a need but also an obligation.

Go to :