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Kim, Jung, Lee, Kim, Kim, Choi, Lee, and Park: A systematic review and meta-analysis of blood transfusion rates during liver resection by country
Original Article
Basic Surgical Topics

Annals of Surgical Treatment and Research 2023; 105(6): 404-416.

Published online: 29 November 2023

DOI: https://doi.org/10.4174/astr.2023.105.6.404

A systematic review and meta-analysis of blood transfusion rates during liver resection by country

Seonju Kim1, Yun Kyung Jung2, Kyeong Geun Lee2, Kyeong Sik Kim2, Hanjun Kim2, Dongho Choi2, Sumi Lee2, Boyoung Park3

1Department of Public Health Sciences, Hanyang University College of Medicine, Seoul, Korea.

2Department of Surgery, Hanyang University College of Medicine, Seoul, Korea.

3Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.

Corresponding Author: Boyoung Park. Department of Medicine, Hanyang University College of Medicine, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea. Tel: +82-2-2220-0682, Fax: +82-31-2220-0699, hayejine@hanyang.ac.kr

Received 18 July 2023       Revised 15 September 2023       Accepted 9 October 2023

Copyright © 2023, the Korean Surgical Society

The Korean Surgical Society

https://creativecommons.org/licenses/by-nc/4.0/
Annals of Surgical Treatment and Research is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

This study aimed to determine the blood transfusion rates during liver resection by country to prepare a basis for patient blood management policy.

Methods

Relevant articles from January 2020 to December 2022 were identified through an electronic database search. Meta-analyses were performed using fixed- or random-effects models. Study heterogeneity was assessed using the Q-test and I2 test. Publication bias was evaluated using funnel plots and Egger’s and Begg’s tests.

Results

Of 104 studies (103,778 participants), the mean transfusion rate was 16.20%. Korea’s rate (9.72%) was lower than Western (14.97%) and other Eastern nations (18.61%). Although open surgery rates were alike (approximately 25%) globally, Korea’s minimally invasive surgery rate was lower (6.28% vs. ≥10%). Odds ratios (ORs) indicated a higher transfusion risk in open surgeries than minimally invasive surgery, especially in Korea (8.82; 95% confidence interval [CI], 5.55–14.02) compared to other Eastern (OR, 2.57) and Western countries (OR, 2.20). For liver resections due to hepatocellular carcinoma and benign diseases, Korea’s rates (10.86% and 15.62%) were less than in Eastern (18.90% and 29.81%) and Western countries (20.15% and 25.22%).

Conclusion

Korea showed a lower transfusion rate during liver resection than other countries. In addition to the patient’s characteristics, including diagnosis and surgical methods, differences in the medical environment affect blood transfusion rates during liver resection.

Keywords: Blood transfusion, Hepatectomy, Patient blood management

INTRODUCTION

Liver resection is the primary curative treatment for hepatobiliary malignancies. Advancements in surgical techniques and anesthetic care have improved the outcomes of liver surgery in recent decades [1]. The perioperative mortality rate of liver resection, which previously exceeded 10%, has decreased by 2%–4% [23]. Among the factors associated with the prognosis of liver resection, blood loss during liver resection is an important factor associated with postoperative complications, long-term outcomes, and survival [456]. Despite efforts to minimize blood transfusion during liver surgery, the perioperative transfusion rates remain high, ranging from 9% to 65%, and exhibit considerable variation between institutions, types of surgery, or patient characteristics [47].
Various strategies have been investigated to reduce perioperative blood loss and its unfavorable sequela [4]. Although patient blood management (PBM), a multidisciplinary patient-centered approach focusing on the minimization of blood product use and improvement of patient outcomes, has been introduced as the standard of care for transfusion medicine [8], the concept of PBM was introduced to liver surgery relatively late compared to other surgeries owing to several specific concerns regarding liver resection [3]. However, the importance of reducing blood transfusion through PBM has been raised [39]. Individual studies in Korea showed transfusion rates of 29% for laparoscopic hepatectomies, 24.5% for laparoscopic major liver resections, and 9% for left hemihepatectomies [9101112], which were comparable to those in previous studies. However, other types of surgery, such as hip arthroplasty or knee arthroplasty, showed a very high transfusion rate compared to other countries despite a decreasing trend [1314]. The excess demand for blood compared with availability by blood donation has been an important issue in the Korean blood management system; thus, in addition to encouraging blood donation and research on blood resources, the minimization of transfusion is required [15].
In combination with high transfusion rates during liver surgery in general and higher transfusion rates for certain types of surgery (hip arthroplasty or knee arthroplasty) in Korea than in other countries, this study aimed to review the blood transfusion rate during liver resection by country to prepare the basis for PBM policy.

METHODS

Data sources and search strategies

This systematic review was performed in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines [16]. Since only previously published literature was included as study materials, ethical approval was not required for this review, and an exemption was granted by the Institutional Review Board of the Hanyang University College of Medicine (No. HYUIRB-202308-004). To assess the most recent evidence, we systematically searched articles published in PubMed, Embase, and Web of Science over the past 3 years as of December 2022. The first search was conducted in March 2023, and the search period was from January 1, 2020, to December 31, 2022.
A combination of Medical Subject Headings (MeSH) and text words was used for liver resection and blood transfusion. The applied search terms were ((((((“transfusion”[Title/Abstract] AND “liver resection”[Title/Abstract]) OR “Hepatectomy”[Title/Abstract]) NOT “systematic review”[Title]) NOT “a review”[Title]) NOT “Meta-Analysis”[Title]) NOT “review”[Title]) AND ((english[Filter]) AND (2020:2022[pdat])).

Inclusion and exclusion criteria

The study population included patients who underwent liver resection, and the search was limited to studies published in English with no age restrictions. Randomized and non-randomized (retrospective and prospective cohort) studies were considered. The exclusion criteria included types of research designs such as multinational institutional studies, editorials, case reports, reviews, and cases where the principal diagnosis was unrelated to the liver (stomach cancer, pancreatic cancer, colon cancer, etc.). Studies involving liver resection due to metastatic cancer to the liver or recurrent liver resection and liver transplantation-related resection of the donor were also excluded. All types of hepatectomy and blood product transfusions were included.

Data collection

One researcher screened the titles and abstracts, and 2 independent researchers conducted a full-text review. Disagreements between the 2 researchers were resolved through discussions. Following the study selection process, data from the identified studies were independently extracted and entered into a predesigned spreadsheet by 2 researchers. The outcomes of interest included transfusion rate by country, primary cause of liver resection (benign liver disease, hepatocellular carcinoma [HCC], and intrahepatic cholangiocarcinoma), surgical method open surgery and minimally invasive surgery (MIS; which included all of laparoscopic surgery, minimally invasive liver resection, and robotic surgery), and cultural area (Korea, Asian countries other than Korea, and Western countries).

Quality assessment

Two researchers independently assessed the methodological quality of the studies. For observational studies, the Risk of Bias Assessment Tool for Non-randomized Studies (RoBANS) was used. The RoBANS covers 6 areas: participant selection, confounding variables, exposure measurement, blinding of outcome assessments, incomplete outcome data, and selective outcome reporting. Each area of the RoBANS tool was judged as “low,” “high,” and “unclear” [1718]. Quality assessment of randomized comparative clinical trials was performed using the risk of bias (RoB) tool. This tool evaluates 5 domains of bias: the randomization process, deviations from intended interventions, missing outcome data, measurement of the outcome, and selection of the reported results. The RoB for each of the 5 domains and overall was described as low, with some concerns, or high [1920].

Analysis

Descriptive results regarding the overall transfusion rate and by country, primary cause of liver resection, surgical method, and cultural area are summarized as the average transfusion proportion. The proportion of transfusions in each study was meta-analyzed using fixed- or random-effects models. Study heterogeneity was assessed using the Q-test and I2 test; if there were significant heterogeneities, a random-effects model was applied; otherwise, a fixed-effects model was applied. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) comparing the blood transfusion rates between open surgery and MIS were estimated and stratified by cultural area. In comparing blood transfusion rates between open surgery and MIS in terms of pooled OR, to increase the comparability, only studies presenting transfusion rates in open surgery and MIS within the same study were considered. Publication bias was evaluated using funnel plots and Egger’s and Begg’s tests. All analyses were performed using RevMan 5.3 (The Nordic Cochrane Center).

RESULTS

The initial search identified 3,854 articles (Fig. 1). After screening titles, abstracts, and quick reviews of the manuscript to identify transfusion-related outcomes not described in the abstract, 189 eligible studies were included in the in-depth full-text review. Finally, 104 papers were included after a full-text review by 2 independent researchers. See Supplementary Table 1 for a summary of the selected literature. A total of 103,778 patients who underwent liver resection across 104 studies met the inclusion criteria. Among the included papers, 3 clinical trials [212223] and 101 retrospective cohort studies [24252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124] were identified, and 41 [222325262733343536424849505152536466676975848586878890919395104106114117118119120121122123124], 12 [29373839414365798099100103], and 14 [2455637273778198102107108109110115] studies were conducted in China, Korea, and Japan, respectively. Studies conducted in these 3 countries accounted for 63.2% of all included studies (Table 1). Supplementary Table 2 and Supplementary Figs. 1, 2 show the biased assessment of the included studies.
According to a meta-analysis, the average transfusion rate in all studies was 16.53%, with an individual study ranging from 0.00% [2941458290110124] to 57.14% [52]. When divided by the countries where the study was conducted, Egypt had the highest blood transfusion rate (49.63%, Table 1), followed by Sweden, Taiwan, the United Kingdom, and China, with a perioperative transfusion rate of more than 20%. However, of these countries with high transfusion rates, except China, the included studies were only 1 or 2.
Table 2 shows transfusion rates by primary diagnosis, surgical methods, and cultural area. When stratified by primary diagnosis, the transfusion rate for the patients with intrahepatic cholangiocarcinoma was 25.71% (range, 10.24%–57.14%), which was higher than those of HCC or benign liver diseases (mean transfusion rate of 17.90% and 20.87%, respectively). Open surgery had a higher transfusion rate than MIS (25.06% vs. 10.07%). The transfusion rate in Korea was lower than those reported in Western and Eastern countries other than Korea (9.72%, 14.97%, and 18.61%, respectively). The range of blood transfusion in Korea was narrow (range, 0.00%–36.64%). When comparing the blood transfusion rate during liver resection in Korea with those in Western and Eastern countries and subdividing it into primary diagnosis and surgical methods, we observed lower blood transfusion rates in all areas (Table 3).
When the probability of transfusion in open surgery was compared with that in MIS, the number of studies included in pooled OR decreased because we included only studies presenting transfusion rates in both open surgery and MIS within the same study. The OR for transfusion was 8.82 (95% CI, 5.55–14.02) in Korea, 2.57 (95% CI, 1.99–3.32) in Asian countries other than Korea, and 2.20 (95% CI, 2.02–2.38) in Western countries (Fig. 2).

DISCUSSION

Liver resection is the curative treatment for malignant and benign liver diseases as well as metastatic cancers of the liver. Despite a decreased transfusion rate during liver resection, transfusion remains a common intervention during hepatic resection. In this study, between 2020 and 2022, the average transfusion rate during liver resection was 16.20%, a lower transfusion rate than that in other systematic reviews, in which the overall proportion of transfusions was 38.3% [4]. A recent study based on hepatic lobectomies performed between 2011 and 2014 registered in a university consortium showed a transfusion rate of 20%, while another study suggested a transfusion rate of at least 25% following liver resection [125]. Although a direct comparison would yield different results, these results support a decreased transfusion rate. Many previous studies on perioperative transfusion did not restrict conditions associated with liver resection. Although colorectal liver metastasis is one of the main indications for liver resection [126], we excluded patients who underwent liver resection for metastatic carcinoma of the liver because of the very high transfusion rate compared to that with other conditions [127].
Previous studies have focused on the detrimental consequences of transfusion during liver resection, risk factors for transfusion, and strategies to reduce blood loss rather than the transfusion rate itself [4125128129]. We focused on the regional differences in transfusion rates in patients who underwent liver resection. There are large differences in the characteristics of liver disease between Asian and Western countries in terms of causes, etiologies, and clinical characteristics, which could affect the outcomes of liver diseases [130131]. In this study, the rate of blood transfusion in Eastern countries other than Korea was higher than in Western countries regardless of surgical method (open or MIS). However, when stratified by liver resection-associated conditions, the transfusion rates for HCC and benign diseases were lower in Eastern countries than in Western countries. In many Asian countries, hepatitis B is the most common cause of liver diseases, including HCC; however, hepatitis C and alcoholic liver disease are the liver diseases that frequently cause HCC in Western countries [131]. Guidelines for the surgical treatment for HCC in Asian countries are more aggressive than those in Western countries, and liver resection is frequently performed in patients with cirrhosis and portal hypertension, whose coagulation disorder and bleeding tendency are higher [131]. Experience with more frequent surgeries and advancements in technology may explain these results.
Lower blood loss and transfusion rates have been reported in laparoscopic surgery than in open surgery; the OR of transfusion during laparoscopic vs. open surgery was 0.36 [132133]. A more recent meta-analysis of comparative cohort studies showed higher volume loss in major laparoscopic liver resection than in open liver manor resection; however, transfusion rates were comparable between the 2 groups [134]. Improved surgical techniques, such as the Glissonian approach, selective clamping, intraoperative ultrasonography, argon beam coagulation, and staplers, help achieve hemostasis and reduce transfusion [134]. In this study, despite the limited number of included studies to estimate pooled OR, the ORs of the transfusion rate of open surgery compared with those of MIS in Asian and Western countries were 2.57 and 2.20, respectively, which were comparable to the OR of previous meta-analyses comparing laparoscopic vs. open surgery [132133]. In Korea, only 3 studies presenting transfusion rates in both MIS and open surgery were included during the study period, and the OR was 8.8. When comparing the number of MIS and open surgeries included in the estimation of pooled OR, the number of MIS was higher than that of open surgery in Korea. However, the number of MIS was lower than that of open surgery in Eastern countries other than Korea and Western countries. Therefore, the improved techniques in Korea could be expected to yield a wide gap in transfusion rate between MIS and open surgery.
Among Asian countries, the transfusion rate of open surgery in Korea was lower than that in other Asian countries, irrespective of diagnosis and surgical methods. When stratified by surgical method, the differences in transfusion rate during open surgery in Korea, Eastern, and Western nations were minimal (approximately 25%); however, the differences in transfusion rate during MIS were significantly lower in Korea than in other Eastern and Western countries. A multicenter study regarding laparoscopic liver resection from 2001 to 2011 showed an intraoperative transfusion rate of 24.5% [11]; thus, after 2011, a significant decrease in transfusion rate during MIS in Korea was identified. Korea has implemented strict blood transfusion management since establishing blood transfusion guidelines in 2009 [135]. Accordingly, blood transfusions for liver disease among all diseases in Korea decreased from 2.94% in 2009 to 2.71% in 2018 [136]. This may be explained by the fact that in Korea, blood transfusion rates are higher in women than in men [136], and liver disease is more common in men than in women [137]. Additionally, it appears to result from efforts to reduce massive bleeding, including advances in laparoscopic liver resection techniques, selective hepatic blood flow blockage during hepatectomy, low central venous pressure maintenance, and sophisticated liver parenchymal dissection.
This study has several limitations. Primarily, although we performed a subgroup analysis according to the primary diagnosis and surgical methods, inherent heterogeneity between studies existed. Within the HCC group, the size and number of tumors may differ, as well as the underlying characteristics of the patients; thus, these heterogeneities might affect perioperative transfusion. Additionally, the confounding variables considered in each study differed. To identify the transfusion rate in recent studies, we restricted the articles included in the meta-analysis to those published within 3 years, but there would be changes in surgical and adjuvant therapies that might affect blood loss and transfusion within the time period. All included studies were observational; thus, there is a possibility of selection bias, publication bias, or bias due to confounding factors. In addition, preoperative procedures that attempted to reduce blood loss and transfusion were not assessed.
In this study, we analyzed the global transfusion rate during liver resection in recent studies. Although there is evidence of a decreasing prevalence of perioperative blood transfusion during liver resection, transfusion remains a common intervention. In addition to patient diagnosis and surgical methods, differences in culture and medical environment according to race and geographic location also affect blood transfusion rates during liver resection. Therefore, nationwide PBM strategies should be implemented to ensure successful PBM results.

Notes

Fund/Grant Support: This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI22C1880).

Conflict of Interest: No potential conflict of interest relevant to this article was reported.

Author Contribution:

  • Conceptualization: SK, YKJ, KGL, KSK, HK, DC, SL.

  • Formal Analysis, Project Administration: SK, BP.

  • Investigation, Methodology: SK, YKJ.

  • Writing – Original Draft: All authors.

  • Writing – Review & Editing: All authors.

References

1. Mise Y, Sakamoto Y, Ishizawa T, Kaneko J, Aoki T, Hasegawa K, et al. A worldwide survey of the current daily practice in liver surgery. Liver Cancer. 2013; 2:55–66. PMID: 24159597.
crossref
2. Martin AN, Kerwin MJ, Turrentine FE, Bauer TW, Adams RB, Stukenborg GJ, et al. Blood transfusion is an independent predictor of morbidity and mortality after hepatectomy. J Surg Res. 2016; 206:106–112. PMID: 27916348.
crossref
3. Hallet J, Jayaraman S, Martel G, Ouellet JB, Lin Y, McCluskey S, et al. Patient blood management for liver resection: consensus statements using Delphi methodology. HPB (Oxford). 2019; 21:393–404. PMID: 30446290.
crossref
4. Bennett S, Baker LK, Martel G, Shorr R, Pawlik TM, Tinmouth A, et al. The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review. HPB (Oxford). 2017; 19:321–330. PMID: 28161216.
crossref
5. Dhar VK, Wima K, Lee TC, Morris MC, Winer LK, Ahmad SA, et al. Perioperative blood transfusions following hepatic lobectomy: a national analysis of academic medical centers in the modern era. HPB (Oxford). 2019; 21:748–756. PMID: 30497896.
crossref
6. Lu Q, Zhang J, Gao WM, Lv Y, Zhang XF, Liu XM. Intraoperative blood transfusion and postoperative morbidity following liver resection. Med Sci Monit. 2018; 24:8469–8480. PMID: 30470732.
crossref
7. Lucas DJ, Schexneider KI, Weiss M, Wolfgang CL, Frank SM, Hirose K, et al. Trends and risk factors for transfusion in hepatopancreatobiliary surgery. J Gastrointest Surg. 2014; 18:719–728. PMID: 24323432.
crossref
8. Franchini M, Marano G, Veropalumbo E, Masiello F, Pati I, Candura F, et al. Patient blood management: a revolutionary approach to transfusion medicine. Blood Transfus. 2019; 17:191–195. PMID: 31246561.
9. Jung YK, Choi D. Patient blood management in hepatobiliary and pancreatic surgery. Hanyang Med Rev. 2018; 38:56–61.
crossref
10. Namgoong JM, Kim KH, Park GC, Jung DH, Song GW, Ha TY, et al. Comparison of laparoscopic versus open left hemihepatectomy for left-sided hepatolithiasis. Int J Med Sci. 2014; 11:127–133. PMID: 24465157.
crossref
11. Hwang DW, Han HS, Yoon YS, Cho JY, Kwon Y, Kim JH, et al. Laparoscopic major liver resection in Korea: a multicenter study. J Hepatobiliary Pancreat Sci. 2013; 20:125–130. PMID: 23001191.
crossref
12. Yoon YS, Han HS, Cho JY, Yoon CJ, Kim JH. Laparoscopic approach for treatment of multiple hepatocellular carcinomas. Surg Endosc. 2012; 26:3133–3140. PMID: 22538699.
crossref
13. Suh YS, Choi HS, Lee JS, Jang BW, Hwang J, Song MG, et al. Transfusion trends of knee arthroplasty in korea: a nationwide study using the Korean National Health Insurance Service Sample Data. Int J Environ Res Public Health. 2022; 19:5982. PMID: 35627518.
crossref
14. Suh YS, Lee JJ, Nho JH, Lee JJ, Won SH, Yang HJ. Transfusion trends in hip arthroplasty in Korea: a nationwide study by the Korean National Health Insurance Service. Transfusion. 2019; 59:2324–2333. PMID: 31022315.
crossref
15. Kim HO. Current state of blood management services in Korea. Ann Lab Med. 2022; 42:306–313. PMID: 34907100.
crossref
16. Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009; 339:b2535. PMID: 19622551.
crossref
17. Kim SY, Park JE, Lee YJ, Seo HJ, Sheen SS, Hahn S, et al. Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity. J Clin Epidemiol. 2013; 66:408–414. PMID: 23337781.
crossref
18. Nam S, Pritchard KT, Bae S, Hong I. Cross-national comparisons of cognitive and physical health in older adults across China, Japan, and Korea: a systematic review. Inquiry. 2021; 58:469580211062451. PMID: 34898332.
19. Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011; 343:d5928. PMID: 22008217.
crossref
20. Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019; 366:l4898. PMID: 31462531.
crossref
21. Martel G, Baker L, Wherrett C, Fergusson DA, Saidenberg E, Workneh A, et al. Phlebotomy resulting in controlled hypovolaemia to prevent blood loss in major hepatic resections (PRICE-1): a pilot randomized clinical trial for feasibility. Br J Surg. 2020; 107:812–823. PMID: 31965573.
crossref
22. Gao X, Xiong Y, Huang J, Zhang N, Li J, Zheng S, et al. The effect of mechanical ventilation with low tidal volume on blood loss during laparoscopic liver resection: a randomized controlled trial. Anesth Analg. 2021; 132:1033–1041. PMID: 33060490.
crossref
23. Yu L, Sun H, Jin H, Tan H. The effect of low central venous pressure on hepatic surgical field bleeding and serum lactate in patients undergoing partial hepatectomy: a prospective randomized controlled trial. BMC Surg. 2020; 20:25. PMID: 32019557.
crossref
24. Bekki T, Abe T, Amano H, Hattori M, Kobayashi T, Nakahara M, et al. Impact of low skeletal muscle mass index and perioperative blood transfusion on the prognosis for HCC following curative resection. BMC Gastroenterol. 2020; 20:328. PMID: 33028209.
crossref
25. Cai J, Zheng J, Xie Y, Kirih MA, Jiang G, Liang Y, et al. A novel simple intra-corporeal Pringle maneuver for laparoscopic hemihepatectomy: how we do it. Surg Endosc. 2020; 34:2807–2813. PMID: 32206920.
crossref
26. Chen G, Tian F, Zhao X, Chen Y, Peng T, Cui J, et al. Perihilar hepatectomy for hepatolithiasis with compressed hilar bile duct induced by perihilar hyperplasia of liver. J Invest Surg. 2020; 33:505–513. PMID: 30543132.
crossref
27. Chen GX, Qi CY, Hu WJ, Wang XH, Hua YP, Kuang M, et al. Perioperative blood transfusion has distinct postsurgical oncologic impact on patients with different stage of hepatocellular carcinoma. BMC Cancer. 2020; 20:487. PMID: 32471389.
crossref
28. Chen TH, Yang HR, Jeng LB, Hsu SC, Hsu CH, Yeh CC, et al. Laparoscopic liver resection: experience of 436 cases in one center. J Gastrointest Surg. 2019; 23:1949–1956. PMID: 30421118.
crossref
29. Choi YI. The usefulness of the totally intra-corporeal pringle maneuver with Penrose drain tube during laparoscopic left side liver resection. Ann Hepatobiliary Pancreat Surg. 2020; 24:252–258. PMID: 32843589.
crossref
30. Clark J, Mavroeidis VK, Lemmon B, Briggs C, Bowles MJ, Stell DA, et al. Intention to treat laparoscopic versus open hemi-hepatectomy: a paired case-matched comparison study. Scand J Surg. 2020; 109:211–218. PMID: 31131722.
crossref
31. Cloyd JM, Mizuno T, Kawaguchi Y, Lillemoe HA, Karagkounis G, Omichi K, et al. Comprehensive complication index validates improved outcomes over time despite increased complexity in 3707 consecutive hepatectomies. Ann Surg. 2020; 271:724–731. PMID: 30339628.
crossref
32. D’Hondt M, Willems E, Parmentier I, Pottel H, De Meyere C, Vansteenkiste F, et al. Laparoscopic liver resection for liver tumours in proximity to major vasculature: a single-center comparative study. Eur J Surg Oncol. 2020; 46(4 Pt A):539–547. PMID: 31668978.
crossref
33. Hu M, Chen K, Zhang X, Li C, Song D, Liu R. Robotic, laparoscopic or open hemihepatectomy for giant liver haemangiomas over 10 cm in diameter. BMC Surg. 2020; 20:93. PMID: 32375738.
crossref
34. Huang Y, Zeng J, Liu T, Lin X, Guo P, Zeng J, et al. Prognostic significance of elevated preoperative serum CA125 levels after curative hepatectomy for hepatocellular carcinoma. Onco Targets Ther. 2020; 13:4559–4567. PMID: 32547086.
35. Jia J, Zhang J, Shao Q, Wang Y, Qian B, Hu T, et al. Efficacy of surgical treatment on different sizes of hepatitis B virus-related hepatocellular carcinoma and prognostic analysis. J BUON. 2020; 25:1866–1874. PMID: 33099926.
36. Ju M, Xu F, Zhao W, Dai C. Efficacy and factors affecting the choice of enucleation and liver resection for giant hemangioma: a retrospective propensity score-matched study. BMC Surg. 2020; 20:271. PMID: 33160352.
crossref
37. Kim HJ, Cho JY, Han HS, Yoon YS, Lee HW, Lee JS, et al. Improved outcomes of major laparoscopic liver resection for hepatocellular carcinoma. Surg Oncol. 2020; 35:470–474. PMID: 33096444.
crossref
38. Kim JH, Kim H. Modified liver hanging maneuver in laparoscopic major hepatectomy: the learning curve and evolution of indications. Surg Endosc. 2020; 34:2742–2748. PMID: 31712899.
crossref
39. Lee JY, Rho SY, Han DH, Choi JS, Choi GH. Unplanned conversion during minimally invasive liver resection for hepatocellular carcinoma: risk factors and surgical outcomes. Ann Surg Treat Res. 2020; 98:23–30. PMID: 31909047.
crossref
40. Machado MA, Makdissi F, Surjan R. Laparoscopic glissonean approach: making complex something easy or making suitable the unsuitable? Surg Oncol. 2020; 33:196–200. PMID: 31307848.
crossref
41. Saad MR, Choi Y, Han HS, Yoon YS, Cho JY, Lee JS, et al. Solo single-incision laparoscopic liver resection: a cohort series. ANZ J Surg. 2020; 90:1108–1111. PMID: 32378778.
crossref
42. Shen J, Ni Z, Qian Y, Wang B, Zheng S. Clinical prediction score for superficial surgical site infections: Real-life data from a retrospective single-centre analysis of 812 hepatectomies. Int Wound J. 2020; 17:16–20. PMID: 31646746.
crossref
43. Shin Y, Rhu J, Choi GS, Kim JM, Joh JW, Kwon CH. Feasibility of laparoscopic liver resection for liver cavernous hemangioma: a single-institutional comparative study. Ann Hepatobiliary Pancreat Surg. 2020; 24:137–143. PMID: 32457257.
crossref
44. Sucandy I, Attili A, Spence J, Bordeau T, Ross S, Rosemurgy A. The impact of body mass index on perioperative outcomes after robotic liver resection. J Robot Surg. 2020; 14:41–46. PMID: 30707422.
crossref
45. Tabath M, Lim C, Goumard C, Scatton O. Surgical glove technique for laparoscopic liver resection. J Gastrointest Surg. 2020; 24:1912–1919. PMID: 32270365.
crossref
46. Tai YH, Wu HL, Mandell MS, Tsou MY, Chang KY. The association of allogeneic blood transfusion and the recurrence of hepatic cancer after surgical resection. Anaesthesia. 2020; 75:464–471. PMID: 31573678.
crossref
47. Tee MC, Chen L, Peightal D, Franko J, Kim PT, Brahmbhatt RD, et al. Minimally invasive hepatectomy is associated with decreased morbidity and resource utilization in the elderly. Surg Endosc. 2020; 34:5030–5040. PMID: 31820156.
crossref
48. Tian YL, Ji JJ, Chen LN, Cui XL, Liu ST, Mao L, Qiu YD, Li BB. Risk factors for long-term prognosis of hepatocellular carcinoma patients after anatomic hepatectomy. World J Clin Cases. 2020; 8:713–722. PMID: 32149055.
crossref
49. Wang XH, Liao B, Hu WJ, Tu CX, Xiang CL, Hao SH, et al. Novel models predict postsurgical recurrence and overall survival for patients with hepatitis B virus-related solitary hepatocellular carcinoma ≤10 cm and without portal venous tumor thrombus. Oncologist. 2020; 25:e1552–e1561. PMID: 32663354.
crossref
50. Wang Y, Fang J, Lin L, Pan L, Nan J, Cui X, et al. Laparoscopic versus open hemihepatectomy: a 1:1 matched analysis. Ann Transl Med. 2020; 8:431. PMID: 32395475.
crossref
51. Yi Y, Weng J, Zhou C, Liu G, Ren N. Laparoscopic versus open left hemihepatectomy for hepatocellular carcinoma: a propensity score matching analysis. Transl Cancer Res. 2020; 9:5484–5492. PMID: 35117913.
crossref
52. Zhang Y, Dou C, Wu W, Liu J, Jin L, Hu Z, et al. Total laparoscopic versus open radical resection for hilar cholangiocarcinoma. Surg Endosc. 2020; 34:4382–4387. PMID: 31664578.
crossref
53. Zhou JM, He XG, Wang M, Zhao YM, Shu L, Wang LR, et al. Enhanced recovery after surgery program in the patients undergoing hepatectomy for benign liver lesions. Hepatobiliary Pancreat Dis Int. 2020; 19:122–128. PMID: 31983674.
crossref
54. Al Khaldi M, Gryspeerdt F, Carrier FM, Bouchard C, Simoneau È, Rong Z, et al. Effect of intraoperative hypovolemic phlebotomy on transfusion and clinical outcomes in patients undergoing hepatectomy: a retrospective cohort study. Can J Anaesth. 2021; 68:980–990. PMID: 33945107.
crossref
55. Aoki T, Kubota K, Matsumoto T, Nitta H, Otsuka Y, Wakabayashi G, et al. Safety assessment of laparoscopic liver resection: a project study of the Endoscopic Liver Surgery Study Group of Japan. J Hepatobiliary Pancreat Sci. 2021; 28:470–478. PMID: 33609320.
crossref
56. Bednarsch J, Czigany Z, Lurje I, Trautwein C, Lüdde T, Strnad P, et al. Intraoperative transfusion of fresh frozen plasma predicts morbidity following partial liver resection for hepatocellular carcinoma. J Gastrointest Surg. 2021; 25:1212–1223. PMID: 32495137.
crossref
57. Boillot O, Cayot B, Guillaud O, Crozet-Chaussin J, Hervieu V, Valette PJ, et al. Partial major hepatectomy with cyst fenestration for polycystic liver disease: indications, short and long-term outcomes. Clin Res Hepatol Gastroenterol. 2021; 45:101670. PMID: 33722781.
crossref
58. Fagenson AM, Gleeson EM, Nabi F, Lau KN, Pitt HA. When does a Pringle Maneuver cause harm? HPB (Oxford). 2021; 23:587–594. PMID: 32933844.
crossref
59. Galun D, Bogdanovic A, Zivanovic M, Zuvela M. Short- and long-term outcomes after hepatectomy in elderly patients with hepatocellular carcinoma: an analysis of 229 cases from a developing country. J Hepatocell Carcinoma. 2021; 8:155–165. PMID: 33791251.
crossref
60. Goh BK, Syn N, Lee SY, Koh YX, Teo JY, Kam JH, et al. Impact of liver cirrhosis on the difficulty of minimally-invasive liver resections: a 1:1 coarsened exact-matched controlled study. Surg Endosc. 2021; 35:5231–5238. PMID: 32974782.
crossref
61. Hobeika C, Cauchy F, Fuks D, Barbier L, Fabre JM, Boleslawski E, et al. Laparoscopic versus open resection of intrahepatic cholangiocarcinoma: nationwide analysis. Br J Surg. 2021; 108:419–426. PMID: 33793726.
62. Hue JJ, Katayama E, Markt SC, Rothermel LD, Hardacre JM, Ammori JB, et al. Association between operative approach and venous thromboembolism rate following hepatectomy: a propensity-matched analysis. J Gastrointest Surg. 2021; 25:2778–2787. PMID: 33236321.
crossref
63. Inoue Y, Ishii M, Fujii K, Kitada K, Kuramoto T, Takano Y, et al. The effects of allogeneic blood transfusion in hepatic resection. Am Surg. 2021; 87:228–234. PMID: 32927956.
crossref
64. Ke Q, Wang L, Lin Z, Lou J, Zheng S, Bi X, et al. Prognostic value of lymph node dissection for intrahepatic cholangiocarcinoma patients with clinically negative lymph node metastasis: a multi-center study from China. Front Oncol. 2021; 11:585808. PMID: 33777738.
crossref
65. Kim JM, Rhu J, Ha SY, Choi GS, Kwon CH, Kim G, et al. Realization of improved outcomes following liver resection in hepatocellular carcinoma patients aged 75 years and older. Ann Surg Treat Res. 2021; 101:257–265. PMID: 34796141.
crossref
66. Li H, Li J, Ren B, Wang J, Xu L, Wang G, Wu H. Parenchyma-sparing hepatectomy improves salvageability and survival for solitary small intrahepatic cholangiocarcinoma. HPB (Oxford). 2021; 23:882–888. PMID: 33187828.
crossref
67. Li J, Huang L, Liu C, Qiu M, Yan J, Yan Y, et al. Risk factors and clinical outcomes of extrahepatic recurrence in patients with post-hepatectomy recurrent hepatocellular carcinoma. ANZ J Surg. 2021; 91:1174–1179. PMID: 33724680.
crossref
68. Lopez-Lopez V, Brusadin R, López-Conesa A, Capel A, Navarro-Barrios Á, Cayuela V, et al. Preoperative transarterial chemoembolization for laparoscopic liver resection in Child A cirrhotic patients with hepatocellular carcinoma. Langenbecks Arch Surg. 2021; 406:763–771. PMID: 33411038.
crossref
69. Lv X, Zhang L, Yu H, Yu X. Laparoscopic hepatectomy for hepatocellular carcinoma: short- and long-term outcomes with blood loss. Transl Cancer Res. 2021; 10:4303–4315. PMID: 35116289.
crossref
70. Machado MA, Lobo-Filho MM, Mattos BH, Ardengh AO, Makdissi FF. Robotic liver resection: report of the first 50 cases. Arq Gastroenterol. 2021; 58:514–519. PMID: 34909859.
crossref
71. Mahamid A, Fenig Y, Amodeo S, Facciuto L, Vonahrens D, Sulimani O, et al. Limited upper midline incision for major hepatectomy in adults: safety and feasibility. Turk J Surg. 2021; 37:379–386. PMID: 35677482.
crossref
72. Matsumoto M, Yanaga K, Shiba H, Wakiyama S, Sakamoto T, Futagawa Y, et al. Treatment of intrahepatic recurrence after hepatectomy for hepatocellular carcinoma. Ann Gastroenterol Surg. 2021; 5:538–552. PMID: 34337303.
crossref
73. Matsuo Y, Nomi T, Hokuto D, Yoshikawa T, Kamitani N, Sho M. Pulmonary complications after laparoscopic liver resection. Surg Endosc. 2021; 35:1659–1666. PMID: 32285208.
crossref
74. Ninh KV, Nguyen NQ, Trinh SH, Pham AG, Doan TN. The application of selective hepatic inflow vascular occlusion with anterior approach in liver resection: effectiveness in managing major complications and long-term survival. Int J Hepatol. 2021; 2021:6648663. PMID: 34007489.
crossref
75. Peng T, Wang L, Cui H, Li X, Liu M, Yu J, et al. Impact of perioperative allogeneic blood transfusion on the long-term prognosis of patients with different stage tumors after radical resection for hepatocellular carcinoma. Eur J Surg Oncol. 2021; 47(3 Pt B):620–627. PMID: 32988700.
crossref
76. Reese T, Pagel G, Bause BA, von Rittberg Y, Wagner KC, Oldhafer KJ. Complex liver resections for intrahepatic cholangiocarcinoma. J Clin Med. 2021; 10:1672. PMID: 33924732.
crossref
77. Ryu T, Takami Y, Wada Y, Sasaki S, Imamura H, Ureshino H, et al. Combined hepatectomy and microwave ablation for multifocal hepatocellular carcinoma: long-term outcomes and prognostic factors. Asian J Surg. 2021; 44:186–191. PMID: 32473893.
crossref
78. Shehta A, Farouk A, Fouad A, Aboelenin A, Elghawalby AN, Said R, et al. Post-hepatectomy liver failure after hepatic resection for hepatocellular carcinoma: a single center experience. Langenbecks Arch Surg. 2021; 406:87–98. PMID: 32778915.
crossref
79. Shin H, Cho JY, Han HS, Yoon YS, Lee HW, Lee JS, et al. Risk factors and long-term implications of unplanned conversion during laparoscopic liver resection for hepatocellular carcinoma located in anterolateral liver segments. J Minim Invasive Surg. 2021; 24:191–199. PMID: 35602860.
crossref
80. Sim JH, Kim SH, Jun IG, Kang SJ, Kim B, Kim S, et al. The association between prognostic nutritional index (PNI) and intraoperative transfusion in patients undergoing hepatectomy for hepatocellular carcinoma: a retrospective cohort study. Cancers (Basel). 2021; 13:2508. PMID: 34063772.
crossref
81. Takata H, Hirakata A, Ueda J, Yokoyama T, Maruyama H, Taniai N, et al. Prediction of portal vein thrombosis after hepatectomy for hepatocellular carcinoma. Langenbecks Arch Surg. 2021; 406:781–789. PMID: 33640991.
crossref
82. Vandermeulen M, Lim C, Goumard C, Scatton O. Standardized technique of selective left liver vascular exclusion during laparoscopic liver resection for benign and malignant tumors. J Gastrointest Surg. 2021; 25:2720–2725. PMID: 34131863.
crossref
83. Villagomez D, Shah M, Marti F, Orozco G, Davenport D, Gupta M, et al. Hepatic steatosis is associated with an increased risk of postoperative infections and perioperative transfusion requirements in patients undergoing hepatectomy. World J Surg. 2021; 45:3654–3659. PMID: 34546385.
crossref
84. Wang JC, Hou JY, Chen JC, Xiang CL, Mao XH, Yang B, et al. Development and validation of prognostic nomograms for single large and huge hepatocellular carcinoma after curative resection. Eur J Cancer. 2021; 155:85–96. PMID: 34371445.
crossref
85. Wang L, Lin N, Lin K, Xiao C, Wang R, Chen J, et al. The clinical value of postoperative transarterial chemoembolization for resectable patients with intermediate hepatocellular carcinoma after radical hepatectomy: a propensity score-matching study. J Gastrointest Surg. 2021; 25:1172–1183. PMID: 32440804.
crossref
86. Zhao Z, Yin Z, Pan L, Li C, Hu M, Lau WY, et al. Robotic hepatic resection in postero-superior region of liver. Updates Surg. 2021; 73:1007–1014. PMID: 33030697.
crossref
87. Zheng J, Feng X, Liang Y, Cai J, Shi Z, Kirih MA, et al. Safety and feasibility of laparoscopic liver resection for hepatocellular carcinoma with clinically significant portal hypertension: a propensity score-matched study. Surg Endosc. 2021; 35:3267–3278. PMID: 32632488.
crossref
88. Zhou Y, Ouyang J, Wang Z, Chen X, Zhu R, Li Q, et al. A novel internal cold circulation radiofrequency-assisted device for liver transection. Int J Hyperthermia. 2021; 38:308–315. PMID: 33627010.
crossref
89. Baumgartner R, Gilg S, Björnsson B, Hasselgren K, Ghorbani P, Sauter C, et al. Impact of post-hepatectomy liver failure on morbidity and short- and long-term survival after major hepatectomy. BJS Open. 2022; 6:zrac097. PMID: 35849062.
crossref
90. Cai JP, Chen W, Chen LH, Wan XY, Lai JM, Yin XY. Comparison between robotic-assisted and laparoscopic left hemi-hepatectomy. Asian J Surg. 2022; 45:265–268. PMID: 34120821.
crossref
91. Cao B, Hao P, Guo W, Ye X, Li Q, Su X, et al. A predictive model for blood transfusion during liver resection. Eur J Surg Oncol. 2022; 48:1550–1558. PMID: 35090795.
crossref
92. Cipriani F, Fiorentini G, Magistri P, Fontani A, Menonna F, Annecchiarico M, et al. Pure laparoscopic versus robotic liver resections: Multicentric propensity score-based analysis with stratification according to difficulty scores. J Hepatobiliary Pancreat Sci. 2022; 29:1108–1123. PMID: 34291591.
crossref
93. Dong Z, Fang K, Sui C, Guo J, Dai B, Geng L, et al. The surgical outcomes and risk factors of giant hepatic haemangiomas: a single centre experience. BMC Surg. 2022; 22:278. PMID: 35843944.
crossref
94. Durán M, Briceño J, Padial A, Anelli FM, Sánchez-Hidalgo JM, Ayllón MD, et al. Short-term outcomes of robotic liver resection: an initial single-institution experience. World J Hepatol. 2022; 14:224–233. PMID: 35126850.
95. Fok AJ, She WH, Ma KW, Tsang SH, Dai WC, Chan AC, et al. Adjuvant transarterial chemotherapy for margin-positive resection of hepatocellular carcinoma-a propensity score matched analysis. Langenbecks Arch Surg. 2022; 407:245–257. PMID: 34406489.
crossref
96. Hawksworth J, Radkani P, Nguyen B, Belyayev L, Llore N, Holzner M, et al. Improving safety of robotic major hepatectomy with extrahepatic inflow control and laparoscopic CUSA parenchymal transection: technical description and initial experience. Surg Endosc. 2022; 36:3270–3276. PMID: 34370124.
crossref
97. Herman P, Fonseca GM, Coelho FF, Kruger JA, Makdissi FF, Jeismann VB, et al. Two decades of liver resection with a multidisciplinary approach in a single institution: what has changed?: analysis of 1409 cases. Clinics (Sao Paulo). 2022; 77:100088. PMID: 35901605.
98. Imai E, Morohashi Y, Mishima K, Ozaki T, Igarashi K, Wakabayashi G. A goal-directed therapy protocol for preventing acute kidney injury after laparoscopic liver resection: a retrospective observational cohort study. Surg Today. 2022; 52:1262–1274. PMID: 35044519.
crossref
99. Jo SJ, Rhu J, Kim JM, Choi GS, Joh JW. Indications for open hepatectomy in the era of laparoscopic liver resection: a high volume single institutional study. J Liver Cancer. 2022; 22:146–157. PMID: 37383410.
crossref
100. Jo Y, Cho JY, Han HS, Yoon YS, Lee HW, Lee JS, et al. Development and validation of a difficulty scoring system for laparoscopic liver resection to treat hepatolithiasis. Medicina (Kaunas). 2022; 58:1847. PMID: 36557049.
crossref
101. Kabir T, Syn N, Koh YX, Teo JY, Chung AY, Chan CY, et al. Impact of tumor size on the difficulty of minimally invasive liver resection. Eur J Surg Oncol. 2022; 48:169–176. PMID: 34420824.
crossref
102. Kaibori M, Ichihara N, Miyata H, Kakeji Y, Nanashima A, Kitagawa Y, et al. Surgical outcomes of laparoscopic versus open repeat liver resection for liver cancers: a report from a nationwide surgical database in Japan. J Hepatobiliary Pancreat Sci. 2022; 29:833–842. PMID: 35445565.
crossref
103. Kim JM, Rhu J, Ha SY, Choi GS, Kwon CH, Joh JW. Hepatectomy outcomes in patients with hepatitis C virus-related hepatocellular carcinoma with or without cirrhosis. Ann Surg Treat Res. 2022; 102:1–9. PMID: 35071114.
crossref
104. Lei Z, Cheng N, Si A, Yang P, Guo G, Ma W, et al. A novel nomogram for predicting postoperative liver failure after major hepatectomy for hepatocellular carcinoma. Front Oncol. 2022; 12:817895. PMID: 35359352.
crossref
105. Loncar Y, Tartrat N, Lastennet D, Lemoine L, Vaillant JC, Savier E, et al. Pulmonary infection after hepatic resection: associated factors and impact on outcomes. Clin Res Hepatol Gastroenterol. 2022; 46:101733. PMID: 34146724.
crossref
106. Luo L, He Y, Zhu G, Xiao Y, Song S, Ge X, et al. Hepatectomy after conversion therapy for initially unresectable HCC: what is the difference? J Hepatocell Carcinoma. 2022; 9:1353–1368. PMID: 36578526.
crossref
107. Miyata T, Hayashi H, Yamashita YI, Matsumura K, Higashi T, Imai K, et al. The impact of histologic liver inflammation on oncology and the prognosis of patients undergoing hepatectomy for hepatocellular carcinoma. Ann Surg Oncol. 2022; 29:893–902. PMID: 34595665.
crossref
108. Nakada S, Otsuka Y, Ishii J, Maeda T, Kubota Y, Matsumoto Y, et al. Predictors of a difficult Pringle maneuver in laparoscopic liver resection and evaluation of alternative procedures to assist bleeding control. Surg Today. 2022; 52:1688–1697. PMID: 35767070.
crossref
109. Nanashima A, Hiyoshi M, Imamura N, Yano K, Hamada T, Kitamura E, et al. Liver hanging maneuver is suitable in major hepatectomy for liver malignancies over 5 cm. Turk J Surg. 2022; 38:215–220. PMID: 36846068.
crossref
110. Notake T, Shimizu A, Kubota K, Sugenoya S, Hosoda K, Hayashi H, et al. Right kidney position for laparoscopic liver resection of tumors located in the posterosuperior region. Surg Laparosc Endosc Percutan Tech. 2022; 32:621–626. PMID: 36130715.
crossref
111. Osei-Bordom D, Hall L, Hodson J, Joshi K, Austen L, Bartlett D, et al. Impact of frailty on short-term outcomes after laparoscopic and open hepatectomy. World J Surg. 2022; 46:2444–2453. PMID: 35810214.
crossref
112. Rahimli M, Perrakis A, Gumbs AA, Andric M, Al-Madhi S, Arend J, et al. The LiMAx Test as selection criteria in minimally invasive liver surgery. J Clin Med. 2022; 11:3018. PMID: 35683406.
crossref
113. Schmelzle M, Feldbrügge L, Ortiz Galindo SA, Moosburner S, Kästner A, Krenzien F, et al. Robotic vs. laparoscopic liver surgery: a single-center analysis of 600 consecutive patients in 6 years. Surg Endosc. 2022; 36:5854–5862. PMID: 35641702.
crossref
114. Tan H, Zhou R, Liu L, Si S, Sun Y, Xu L, et al. Comparison of efficacy and safety of laparoscopic and open enucleation for liver hemangioma in the right hemi liver: a retrospective cohort study. Ann Transl Med. 2022; 10:764. PMID: 35965786.
crossref
115. Tanemura A, Mizuno S, Maeda K, Shinkai T, Ito T, Hayasaki A, et al. Resection type is a predictor of postoperative complications in laparoscopic partial liver resection. Surg Endosc. 2022; 36:9054–9063. PMID: 35831677.
crossref
116. Vining CC, Kuchta K, Al Abbas AI, Hsu PJ, Paterakos P, Schuitevoerder D, et al. Bile leak incidence, risk factors and associated outcomes in patients undergoing hepatectomy: a contemporary NSQIP propensity matched analysis. Surg Endosc. 2022; 36:5710–5723. PMID: 35467144.
crossref
117. Wang J, Wang W, Chen X, Ma D, Du G, Xia T, et al. Laparoscopic versus open hepatectomy for intrahepatic cholangiocarcinoma in patients aged 60 and older: a retrospective cohort study. World J Surg Oncol. 2022; 20:396. PMID: 36510298.
crossref
118. Wu X, Zeng N, Hu H, Pan M, Jia F, Wen S, et al. Preliminary exploration on the efficacy of augmented reality-guided hepatectomy for hepatolithiasis. J Am Coll Surg. 2022; 235:677–688. PMID: 36106869.
crossref
119. Xu L, Xu Y, Lı G, Yang B. Effect of perioperative factors on the prognosis of patients with hepatocellular carcinoma who underwent hepatectomy. Turk J Med Sci. 2022; 52:1067–1074. PMID: 36326411.
crossref
120. Xu LN, Xu YY, Li GP, Yang B. Individualized risk estimation for postoperative pulmonary complications after hepatectomy based on perioperative variables. World J Gastrointest Surg. 2022; 14:685–695. PMID: 36158277.
crossref
121. Yang J, Chen K, Zheng C, Chen K, Lin J, Meng Q, et al. Impact of sarcopenia on outcomes of patients undergoing liver resection for hepatocellular carcinoma. J Cachexia Sarcopenia Muscle. 2022; 13:2383–2392. PMID: 35854105.
crossref
122. Yang SY, Yan ML, Duan YF, Feng JK, Ye JZ, Xiang YJ, et al. Perioperative and long-term survival outcomes of laparoscopic versus laparotomic hepatectomy for BCLC stages 0-A hepatocellular carcinoma patients associated with or without microvascular invasion: a multicenter, propensity score matching analysis. Hepatol Int. 2022; 16:892–905. PMID: 35704267.
crossref
123. Yang Y, Peng Y, Chen K, Wei Y, Li B, Liu F. Laparoscopic liver resection with “ultrasonic scalpel mimic CUSA” technique. Surg Endosc. 2022; 36:8927–8934. PMID: 35672503.
crossref
124. Zhang X, Huang Z, Lu H, Yang X, Cao L, Wen Z, et al. Identification of resection plane for anatomical liver resection using ultrasonography-guided needle insertion. Front Surg. 2023; 9:1035315. PMID: 36756661.
crossref
125. Latchana N, Hirpara DH, Hallet J, Karanicolas PJ. Red blood cell transfusion in liver resection. Langenbecks Arch Surg. 2019; 404:1–9.
crossref
126. Chen FL, Wang YY, Liu W, Xing BC. Prognostic factors in colorectal liver metastases patients with various tumor numbers treated by liver resection: a single-center, retrospective study. World J Surg Oncol. 2022; 20:237. PMID: 35854361.
crossref
127. Lyu X, Qiao W, Li D, Leng Y. Impact of perioperative blood transfusion on clinical outcomes in patients with colorectal liver metastasis after hepatectomy: a meta-analysis. Oncotarget. 2017; 8:41740–41748. PMID: 28410243.
crossref
128. Masatsune S, Kimura K, Kashiwagi S, En W, Okazaki Y, Maeda K, et al. Impact of intraoperative blood loss and blood transfusion on the prognosis of colorectal liver metastasis following curative resection. Anticancer Res. 2021; 41:5617–5623. PMID: 34732434.
129. Moggia E, Rouse B, Simillis C, Li T, Vaughan J, Davidson BR, et al. Methods to decrease blood loss during liver resection: a network meta-analysis. Cochrane Database Syst Rev. 2016; 10:CD010683. PMID: 27797116.
crossref
130. Jayaraman T, Lee YY, Chan WK, Mahadeva S. Epidemiological differences of common liver conditions between Asia and the West. JGH Open. 2019; 4:332–339. PMID: 32514433.
crossref
131. Choo SP, Tan WL, Goh BK, Tai WM, Zhu AX. Comparison of hepatocellular carcinoma in Eastern versus Western populations. Cancer. 2016; 122:3430–3446. PMID: 27622302.
crossref
132. Rao A, Rao G, Ahmed I. Laparoscopic or open liver resection?: let systematic review decide it. Am J Surg. 2012; 204:222–231. PMID: 22245507.
crossref
133. Yin Z, Fan X, Ye H, Yin D, Wang J. Short- and long-term outcomes after laparoscopic and open hepatectomy for hepatocellular carcinoma: a global systematic review and meta-analysis. Ann Surg Oncol. 2013; 20:1203–1215. PMID: 23099728.
134. Wang ZY, Chen QL, Sun LL, He SP, Luo XF, Huang LS, et al. Laparoscopic versus open major liver resection for hepatocellular carcinoma: systematic review and meta-analysis of comparative cohort studies. BMC Cancer. 2019; 19:1047. PMID: 31694596.
135. Koo BN, Kwon MA, Kim SH, Kim JY, Moon YJ, Park SY, et al. Korean clinical practice guideline for perioperative red blood cell transfusion from Korean Society of Anesthesiologists. Korean J Anesthesiol. 2019; 72:91–118. PMID: 30513567.
136. Kim H, Ko SY, Gwon JG. Trends of blood transfusion according to diseases in Korea: a 10-year nationwide cohort study. Transfus Med Hemother. 2022; 50:135–143. PMID: 37066054.
137. Kim BH, Park JW. Epidemiology of liver cancer in South Korea. Clin Mol Hepatol. 2018; 24:1–9. PMID: 29249129.

SUPPLEMENTARY MATERIALS

Supplementary Tables 1, 2 and Supplementary Figs. 1, 2 can be found via https://doi.org/10.4174/astr.2023.105.6.404.

Supplementary Fig. 1

Risk of bias graph and summary.
astr-105-404-s001.pdf

Supplementary Fig. 2

Funnel plot.
astr-105-404-s002.pdf

Supplementary Table 1

Summary of selected literature
astr-105-404-s003.pdf

Supplementary Table 2

Bias assessment for non-randomized studies using Risk of Bias Assessment Tool for Non-randomized Studies
astr-105-404-s004.pdf
Fig. 1

Research selection flow chart.

astr-105-404-g001
Fig. 2

Blood transfusion rate in open surgery compared with minimal invasive surgery by geographical region. MIS, minimally invasive surgery; CI, confidence interval; df, degree of freedom.

astr-105-404-g002
Table 1

Average blood transfusion rates by country included in the study

astr-105-404-i001

SD, standard deviation.

Table 2

Average blood transfusion rates by primary diagnosis and surgery and cultural area

astr-105-404-i002

The benign group includes polycystic liver disease, hemangioma, and liver stones. The MIS group included laparoscopic surgery, minimally invasive liver resection, and robotic surgery. The Eastern group includes China, Japan, Singapore, Taiwan, and Vietnam. The Western group includes Belgium, Brazil, France, Serbia, United Kingdom, United States, Canada, Egypt, Germany, Italy, Spain, and Sweden.

SD, standard deviation; HCC, hepatocellular carcinoma; ICC, Intrahepatic cholangiocarcinoma; MIS, minimally invasive surgery.

Table 3

Average blood transfusion rates by geographical region

astr-105-404-i003

The benign group includes polycystic liver disease, hemangioma, and liver stones. The MIS group included laparoscopic surgery, Minimally invasive liver resection, and robotic surgery. The Western group includes Belgium, Brazil, France, Serbia, United Kingdom, United States, Canada, Egypt, Germany, Italy, Spain, and Sweden. The Eastern group includes China, Japan, Singapore, Taiwan, and Vietnam.

SD, standard deviation; HCC, hepatocellular carcinoma; ICC, intrahepatic cholangiocarcinoma; MIS, minimal invasive surgery.

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