Journal List > J Korean Med Sci > v.38(6) > 1516081311

Kim, Kim, Son, Youn, and Lee: Reliability and Validity of the Korean Version of the Ask Suicide-Screening Questions (ASQ)

Abstract

Background

The Ask Suicide-Screening Questions (ASQ) tool is a simple suicide screening tool developed to screen patient suicide risk (SR). The purpose of this study was to verify the reliability and validity of the ASQ tool in hospitalized patients.

Methods

The internal consistency and test-retest reliability of the South Korean version of the ASQ tool were verified in 99 hospitalized patients admitted to a tertiary medical institution in Seoul. To verify the correlations and validity of each convergence with other scales, the Mini-International Neuropsychiatric Interview (MINI), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Satisfaction with Life Scale (SWLS) were also conducted to determine convergent and discriminant validity. Then, the receiver operating characteristic (ROC) curve diagnosis values for suicide and depression levels with the highest correlations were analyzed.

Results

As a result, Cronbach’s alpha was 0.826, and when each item was removed sequentially, Cronbach’s alpha ranged from 0.736–0.840, showing stable internal consistency. Most of the corrected item-total correlation were over 0.500; however, a relatively low correlation was shown for the fourth and fifth questions, which had values of 0.429 and 0.410, respectively. The test-retest reliability was 0.830, and the MINI and PHQ-9 showed high values of 0.872 and 0.672, respectively. The area under the curve (AUC) according to the ASQ diagnosis value was also the highest for the MINI (0.936).

Conclusion

The validity and reliability of the South Korean version of the ASQ tool were demonstrated. Through this validation, the ASQ tool can be used for simple suicide risk screening (SRS) in hospitalized patients.

Graphical Abstract

jkms-38-e41-abf001.jpg

INTRODUCTION

With a suicide rate of 26.9 per 100,000 people, South Korea ranks first among Organization for Economic Co-operation and Development (OECD) countries. Suicide rates had decreased for a time but have continued to increase since 2018.1 In particular, the recent situation of the coronavirus disease 2019 (COVID-19) pandemic induced mental issues such as stress, anxiety, and depression along with financial burdens and a fear of infection, which may have resulted in increased suicidal tendencies.2
Mental illness plays a considerable role in suicide deaths, accounting for 90% of cases. Diagnoses of depression (15.0%), bipolar disorder (10.0%), schizophrenia (10%), and anxiety (11.0%) as well as drug and alcohol use problems3456 are related to suicide deaths.78
Suicide is a process that initiates from suicidal ideation, which leads to planning and behavior. Some people with suicidal ideation actually make suicide attempts.910 Furthermore, those with previous suicide attempts have an increased risk of recurrent suicidal ideation, which leads to an increased risk of suicidal behavior.11 Also, previous suicide attempts are the strongest predictor of future suicide attempts.1213 Therefore, as a preventative measure, early identification of patients with suicide risk (SR) is necessary. Furthermore, among various factors, social isolation experienced by people who are considering attempting suicide can be a strong predictor of SR.14 Increased social isolation in hospitalized patients and during the COVID-19 pandemic may increase SR; therefore, to address SR, proper intervention is required.
Healthcare providers use the Columbia Suicide Severity Rating Scale,15 Patient Safety Screener,16 and Revised Suicidal Behavior Questionnaire17 to identify SR. However, most of the tools developed for mental health examinations in outpatient and primary care clinics require a long time to perform, special education, and high cost and are mainly used only for depression screening.151618
Therefore, institutions with psychiatric wards recognize the necessity of a proven SR screening (SRS) tool to prevent suicide in suicidality risk patients. Among different tools, the Ask Suicide-Screening Questions (ASQ) tool was selected to be investigated in this study. ASQ is a good tool for screening patients at risk of suicide regardless of whether they are inpatients or patients,192021 and is particularly useful in emergency departments.22232425 The ASQ tool was developed by the National Institute of Mental Health (NIMH) in the United States to effectively screen for SR.
The ASQ tool is a test specifically developed for SRS in psychiatric patients and is comprised of five items.22 To confirm the efficacy of this tool, it was developed and validated for patients in general wards such as internal medicine/surgery, and the standard measure for suicide prediction was used for verification.262728 Therefore, this study also verified the reliability and validity of the ASQ SRS tool in psychiatric inpatients and determined appropriateness of the tool as a SR assessment for psychiatric inpatients in South Korea.

METHODS

Participants

One hundred adult patients in their twenties who were admitted to the psychiatric department of a tertiary general hospital in Seoul from May 27, 2021, to December 31, 2021, were selected as participants for this study. Participants understood the study purpose and provided consent directly before participation. Those suffering from psychiatric Axis 2 diseases such as organic psychiatric disorders, intellectual disabilities, or personality disorders, neurological diseases, or significant internal/surgical diseases, and illiterate individuals were excluded from the subjects.

Measures

ASQ suicide screening toolkit

This toolkit was developed by the NIMH in the USA, and is comprised of five questions in the form of a self-report questionnaire. Questions one to four consist of ‘yes’ or ‘no’ responses, and if patients answer ‘yes,’ even to one question, it is regarded as a positive test. With a positive test, patients are required to answer question five, which is a susceptibility evaluation item. If this question is answered with ‘yes,’ which is regarded as positive susceptibility, the patient is considered to be at imminent risk.

Patient Health Questionnaire-9 (PHQ-9)

The PHQ-9 is a self-report test designed to screen for and assess the severity of depression. It includes nine items that apply the diagnostic criteria for major depressive disorder from the Diagnostic and Statistical Manual of Mental Disorders (DSM), and the score ranges from 0 to 27. The Korean version of PHQ-9, which has been proven reliable and valid in a Korean standardization study, was used in this study.29

Generalized Anxiety Disorder-7 (GAD-7)

The GAD-7 anxiety assessment screens for generalized anxiety disorder and evaluates the severity of symptoms. This tool is a simple self-report test with seven questions on a four-point Likert scale.30 This tool screens for generalized anxiety disorder effectively in a short period of time. The Korean version of the GAD-7 was used to evaluate anxiety.31

Satisfaction with Life Scale (SWLS)

Developed by Pavot and Diener (2008) to measure life satisfaction, the SWLS is a self-report scale with five questions.32 It is rated on a Likert seven-point scale, and a higher score indicates greater life satisfaction. In this study, the Korean version of the SWLS was used.33

Mini-International Neuropsychiatric Interview (MINI) suicidality module

The MINI is a simple and structured interview tool developed in USA and Europe in 1998 for the diagnosis of major psychiatric Axis 1 diseases in the DSM-IV and International Classification of Disease, 10th edition (ICD-10) and is used in multicenter clinical research or epidemiological studies. For domestic use, Yoo et al.34 developed a standardized South Korean version in 2006.

Statistical analysis

1) Cronbach’s alpha coefficient and item-total correlation were measured to verify the internal consistency and reliability of the ASQ tool.
2) The coexistence validity was determined to verify the similarity of the ASQ tool and previous SR assessments. For this purpose, the Pearson moment correlation coefficient was analyzed through correlation analysis of the ASQ tool total score, PHQ-9 depression assessment, SWLS, and MINI suicidality module.
3) To confirm the optimal reference score for the ASQ tool, receiver operating characteristic (ROC) curve analysis, which reveals diagnostic accuracy, was performed.
4) The sensitivity and specificity of the ASQ tool reference score were measured by confirming the sensitivity and specificity of each of the reference scores and comparing them with the MINI.
All data were analyzed using SPSS version 27 for Windows (IBM Corp., Armonk, NY, USA) and R 4.2.1 (R Development Core Team, Vienna, Austria; http://www.r-project.org).

Ethics statement

This study was conducted with the approval of the Institutional Bioethics Committee (HYUH-IRB 2020-07-051) from Hanyang University Hospital. Informed consent was obtained from all participants involved in this study.

RESULTS

General participant characteristics

A total of 99 subjects completed the questionnaire. There were 44 males (44.4%) and 55 females (55.6%), and the average age of the subjects was 48.21 ± 15.82 years. Accounting for the largest proportion, 48% of the patients were from internal medicine wards, and there were also inpatient (6.1%) and outpatient (12.1%) psychiatric patients (Table 1).
Table 1

General characteristics of the participants (N = 99)

jkms-38-e41-i001
Variables Values
Sex
Male 44 (44.4)
Female 55 (55.6)
Patients characteristic
Psychiatric (inpatient) 6 (6.1)
Psychiatric (local) 12 (12.1)
Medical 48 (48.5)
Surgical 33 (33.3)
Age, yr 48.21 ± 15.82
20–29 17 (17.2)
30–39 14 (14.1)
40–49 15 (15.2)
50–59 28 (28.3)
> 60 25 (25.3)
Marital status
Never married 35 (35.4)
Married 60 (60.6)
Other status 4 (4.0)
Education
Less than high school 6 (6.1)
High school graduate 43 (43.4)
College graduate 37 (37.4)
More than college graduate 13 (13.1)
Values are presented as number of patients (%) or as mean ± standard deviation.

Reliability

Internal consistency reliability

Cronbach’s alpha coefficient was 0.826 in this study. When each item was removed sequentially, stable internal consistency was observed, with values ranging from 0.736–0.840. Most of the corrected item-total correlations of the ASQ were over 0.500 (0.429–0.793); however, for the questions ‘Have you ever attempted suicide?’ (0.429) and ‘Are you thinking of suicide now?’ (0.441), the correlation was relatively low (Table 2).
Table 2

Reliability statistics of ASQ questionnaire

jkms-38-e41-i002
Variables Values
Inter consistency reliability
Cronbach's Alpha 0.826
Cronbach's Alpha based on Standardized Items 0.817
Cronbach's alpha if item deleted
1. In the past few weeks, have you wished you were dead? 0.736
2. In the past few weeks, have you felt that you or your family would be better off if you were dead? 0.770
3. In the past week, have you been having thoughts about killing yourself? 0.744
4. Have you ever tried to kill yourself? 0.840
5. Are you having thoughts of killing yourself right now? 0.836
Test-retest reliability (n = 21)
Cronbach's alpha 0.929
Cronbach's alpha based on standardized items 0.930
Guttman split-half coefficient 0.830
ASQ = Ask Suicide-Screening Questions

Test-retest reliability

Only 21 subjects responded when the retest was conducted after a week. The test-retest reliability was 0.929, and Guttman’s split-half reliability coefficient was 0.830 (Table 2).

Validity

Factorial validity

For the suitability of item data for factor analysis, the Kaiser-Meyer-Olkin (KMO) sample fit test was performed. The KMO value was 0.760, and Bartlett’s sphericity test showed χ2 = 217.22 (P < 0.001), showing a statistically significant difference, indicating factorial validity (Table 3).
Table 3

KMO and Bartlett validity of the ASQ questionnaire

jkms-38-e41-i003
Variables Values
KMO measure of sampling adequacy 0.760
Bartlett's test of sphericity
Approximately χ2 217.218
Significant 0.000
KMO = Kaiser-Meyer-Olkin, ASQ = Ask Suicide-Screening Questions.

Convergent and discriminant validity

The results of the measured correlation with the PHQ-9 depression assessment, GAD-7 anxiety assessment, and SWLS for reference validity measurement are as follows: There was a significant positive correlation between the PHQ-9 depression assessment (r = 0.672, P < 0.001) and GAD-7 anxiety assessment (r = 0.519, P < 0.001). There was a significant negative correlation with the SWLS (r = −0.510, P < 0.001). The highest correlation was with the MINI (r = 0.872, P < 0.001). Finally, the correlation with the PHQ-10, which combines the tenth question from the PHQ that measures suicidal tendency showed the following correlation values: r = 0.668, P < 0.001 (Table 4).
Table 4

Convergent and discriminant validity

jkms-38-e41-i004
Measurements ASQ PHQ-9 PHQ-10 GAD-7 SWLS MINI
ASQ 1 - - - - -
PHQ-9 0.672a 1 - - - -
PHQ-10 0.668a 0.997a 1 - - -
GAD-7 0.519a 0.737a 0.738a 1 - -
SWLS −0.510a −0.455a −0.452a −0.387a 1 -
MINI 0.872a 0.594a 0.597a 0.478a −0.488a 1
ASQ = Ask Suicide-Screening Questions, PHQ = Patient Health Questionnaire, GAD = Generalized Anxiety Disorder, SWLS = Satisfaction with Life Scale, MINI = Mini-International Neuropsychiatric Interview.
aCorrelation is significant at the 0.01 level (2-tailed).

Factor component matrix and ROC curve analysis

As one factor, the factor standardized loading value of the ASQ tool was evaluated through EFA analysis, which showed high matrix values of 0.920, 0.730, and 0.87 for ASQ-1, ASQ-2, and ASQ-3, respectively. ASQ-4 and ASQ-5 had values of 0.480 and 0.460, respectively, showing component matrix value (Table 5, Fig. 1).
Table 5

Principal component analysis of ASQ

jkms-38-e41-i005
ASQ standardized loadings Values
Items
ASQ-1 0.920
ASQ-2 0.730
ASQ-3 0.870
ASQ-4 0.480
ASQ-5 0.460
Tucker Lewis index of factoring reliability 0.884
RMSEA index 0.156 (0.080–0.241)
Fit based upon off diagonal values 0.980
Correlation of (regression) scores with factors 0.960
ASQ = Ask Suicide-Screening Questions, RMSEA = root mean square error of approximation.
Fig. 1

ASQ Standardized loading based upon correlation matrix.

ASQ = Ask Suicide-Screening Questions.
jkms-38-e41-g001
To determine the accuracy of the ASQ tool as a suicide screening tool, the optimal cut-off point was analyzed with Youden’s index (J) method utilizing the PHQ-9, PHQ-10, MINI scale, ROC curve analysis, sensitivity, and specificity. Thirty patients diagnosed with SR by the ASQ tool showed the highest MINI score with an AUC of 0.958 (95% confidence interval [CI], 0.910–1.007). Similarly, the PHQ-9 and PHQ-10 showed AUC values of 0.859 (95% CI, 0.776–0.943) and 0.855 (95% CI, 0.769–0.940) (Fig. 2), respectively. In the ASQ tool, ASQ-5 is a suicide susceptibility assessment that screens for current suicidal tendencies. In this study, six patients were diagnosed, with similar AUC values of the total ASQ questions (MINI, 0.936; 95% CI, 0.857–1.014; PHQ-9, 0.879; 95% CI, 0.788–0.971; PHQ-10, 0.882; 95% CI, 0.792–0.971). However, when compared with ASQ-5, which showed uniform values (MINI, 0.714; PHQ-9, 0.703; PHQ-10, 0.745), PHQ-10 in ASQ showed highest optimal cut point of 0.889 and other values included MINI, 0.632 and PHQ-9, 0.617 in the optimal cut-off point for the ROC curve (Table 6, Fig. 3).
Fig. 2

PHQ, MINI ROC curve of ASQ.

PHQ = Patient Health Questionnaire, MINI = Mini-International Neuropsychiatric Interview, ROC = receiver operating characteristic, ASQ = Ask Suicide-Screening Questions.
jkms-38-e41-g002
Table 6

ROC curve of ASQ

jkms-38-e41-i006
Variables ASQ ASQ-5 item positive (present suicide)
ASQ
Positive 30 6
Negative 67 91
Area under the ROC curve
PHQ-9 0.859 (0.776–0.943) 0.879 (0.788–0.971)
PHQ-10 0.855 (0.769–0.940) 0.882 (0.792–0.971)
MINI 0.958 (0.910–1.007) 0.936 (0.857–1.014)
ROC curve optimal cut point
PHQ-9 0.617 0.703
PHQ-10 0.889 0.745
MINI 0.632 0.714
ROC = receiver operating characteristic, ASQ = Ask Suicide-Screening Questions, PHQ = Patient Health Questionnaire, MINI = Mini-International Neuropsychiatric Interview.
Fig. 3

PHQ, MINI ROC curve of ASQ-5 item (present suicide screened).

PHQ = Patient Health Questionnaire, MINI = Mini-International Neuropsychiatric Interview, ROC = receiver operating characteristic, ASQ = Ask Suicide-Screening Questions.
jkms-38-e41-g003

DISCUSSION

The reliability and validity of the South Korean version of the ASQ tool were verified in this study. This tool has been used to screen for SR in pediatric and adult inpatients.2228 In particular, a rapid SRS tool is needed for patients admitted to psychiatric wards because they are at high risk from the early stage of admission. Therefore, this study was conducted on 100 patients admitted to a tertiary medical institution in Seoul to verify the reliability and validity of the ASQ tool, which consists of short items, in South Korea.
The internal consistency reliability showed a high value of 0.826 for the reliability of the ASQ tool. The internal consistency was high, when each item was removed, showing high reliability of the ASQ tool.3536 Furthermore, the correlation coefficient between each item and the total ASQ score also showed a statistically significant correlation. Remarkably, ASQ-4 and ASQ-5 showed relatively lower values of 0.429 and 0.447, respectively. In previous studies, ASQ-4, which evaluates past suicidal attempts (e.g., ‘Have you ever attempted suicide?’), is a time parameter that measures lifetime experiences.19 Therefore, when the subject has had any suicidal attempt experiences in their lives, all subsequent ASQ tests are regarded to be positive, regardless of changes in suicidal ideation or risk changes. Therefore, in the case of an ASQ-4-positive patient, the time point of the suicidal attempt should be determined, and this information must be considered according to the responses to ASQ-1–3 to clearly evaluate the current SR.
On the other hand, ASQ-5 evaluates the current SR by asking, ‘Are you thinking of suicide now?’. There were six patients with an ASQ-5 positive result in this study. Similar to ASQ-4, there was relatively low reliability; however, when compared with the total ASQ items, similar screening values were observed in the AUC and ROC curve optimal cut-off point as a suicide screening tool. Therefore, as the questions with low correlation values (ASQ-4 and ASQ-5) are regarded as single factors of the suicidal tendencies of the ASQ tool, and further interviews are required.
Among depression and suicide tools, the ASQ tool showed the highest significant correlation with the MINI, which measures suicidal tendencies. For the symptoms, depression showed a high correlation with suicide. In this study, the total ASQ items and ASQ-5 were separately analyzed, however, ASQ did not show significant difference. This demonstrates the validity and consistency of the ASQ tool as a suicide screening tool.
Similarly, in previous studies, the ASQ tool was considered to have high validity as an SRS tool even for individuals who are not psychiatric inpatients, as the four items from the ASQ tool evaluate the main components of SR.37 Furthermore, the ASQ tool has been researched as a useful tool that can predict adult psychology.192238 The results of this study, which revealed possible SR and psychology predictions, are congruent with those of previous studies.
Retesting was performed a week after the initial ASQ assessment to increase the reliability of this study. The test-retest reliability was high at 0.929, suggesting that ASQ suicidal-positive subjects do not change their suicidal ideations even with the passage of time. Therefore, the ASQ tool is consistent in assessing SR and can be managed as an SRS tool with verification through comparison with other suicide scales.39 In particular, with fewer questions than and similar cutoff values to other SRS tools, the ASQ tool is considered a useful SRS tool. Furthermore, the ASQ tool is useful in screening for suicide even in high-risk groups when used after the depression assessment through investigating the correlation with depression scales.
With these advantages, the American Academy of Child and Adolescent Psychiatry (AACAP) has created a clinical pathway for SRS in pediatric emergency rooms (ERs) and medical/surgical wards using the ASQ tool as an SRS tool,40 and according to a study by LeCloux, healthcare professionals in community and pediatric outpatient hospitals consider the ASQ tool easy to use with its short questions.41 Consequently, the ASQ tool is a valid, reliable, and effective SRS tool. In addition, it has the advantage of rapidly assessing suicide risk in psychiatry and especially in psychiatric emergencies through studies showing that it has high sensitivity, specificity, and NPV as a screening tool for suicide even with the 4 items of ASQ.22
The limitations of this study are as follows. First, it was not possible to measure variables of symptom changes according to each patient’s hospitalization period as the subjects were comprised of only hospitalized psychiatric patients. Second, the subjects were limited to hospitalized psychiatric patients in tertiary medical institutions, and further follow-up study is necessary to generalize the results of this study. Third, accurate measurement was limited as the responses could be denied or minimized due to the characteristics of psychiatric inpatients when they are not hospitalized.
Nevertheless, this study has significance. First, testing and retesting were conducted to confirm reliability, which has been rarely done in previous studies. Furthermore, the diagnostic criteria of the ASQ tool were analyzed as a screening tool through comparison with other suicide and depression tools. Second, accurate standardization was achieved through the reverse translation process performed by an English scholar. Third, unlike most of the previous studies, which were conducted on pediatric22 and adult patients17 in ERs,37 this study measured the validity and reliability of the tool in hospitalized patients who require SRS most significantly.
As the latest SRS tool, the ASQ tool is efficacious and has only short questions that take only 20 seconds, and studies on the ASQ tool have been conducted to verify its effectiveness since 2008. The results of these studies suggest the efficacy and validity of the ASQ tool in various subjects, and the results of this study ensured the reliability and validity of the ASQ tool in South Korea. However, a further suicide safety evaluation question: ‘What if the patient tests positive?’ is raised, and the current research is ongoing. Therefore, safety evaluation and intervention for additional SRS through the verification of the ASQ tool, which was confirmed through this study, should be further explored.
In conclusion, the reliability and validity of the ASQ tool were verified on inpatients in general hospitals. As a result, the ASQ tool showed high internal consistency and test-retest reliability, and its validity was verified through its high correlation with the MINI (suicide tendencies) and PHQ-9 (depression assessment). Furthermore, the high AUC value of the ASQ tool as an SRS tool and optimal cut-off point were identified through ROC curve analysis. Consequently, the ASQ tool is expected to be utilized as a simple and useful SRS tool in inpatients and patients in ERs. In addition, conducting other depressive tendency assessments along with the ASQ tool may contribute to screening and preventing suicide by increasing the stability of suicide screening.

Notes

Disclosure: The authors have no potential conflicts of interest to disclose.

Author Contributions:

  • Conceptualization: Kim HJ, Lee K.

  • Data curation: Kim S.

  • Formal analysis: Kim HJ, Kim S.

  • Investigation: Kim HJ, Son Y, Youn I.

  • Methodology: Kim S, Lee K.

  • Validation: Kim HJ, Lee K.

  • Visualization: Kim HJ, Kim S, Lee K.

  • Writing - original draft: Kim HJ.

  • Writing - review & editing: Lee K.

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