Introduction
Human anatomy is the science that studies the structures of the body in all its dimensions and complexities. Due to its relevance for the consolidation of knowledge in the Health sciences, anatomy has become indispensable to undergraduate courses [
1-
4]. Even with the advent of new methods of teaching in the 21st century, dissection and human specimens study remain the gold standard for the teaching of anatomy and it is established as a vital component to Health education, considering that it contributes significantly to the acquisition of essential clinical abilities and professional safety [
5-
8]. Dissabandara et al. [
9] have reported that the majority of medical students have a positive perception of dissections. In addition, dissection may have an effect on course performance according to the student’s opinion [
10]. It is common knowledge among anatomy professors that the teaching of this science must rely on a prepared environment for students’ learning, as well as integral anatomical specimens, which should be well-preserved and in a sufficient quantity for the number of students, and they must also provide trustworthy knowledge [
11-
13]. Besides that, studying using human specimens, alongside ethical education, stimulates respect to the body and sensibility of future healthcare professionals, providing a genuine understanding of the concept of death [
14-
17].
In Brazil, the regulation for obtaining cadavers for teaching institutions according to the norms of the public authority came to existence in 1992, when a law came into effect supporting the usage of unclaimed bodies within a 30-day period, with the aim of teaching and scientific research [
18]. However, with the increasing number of medical schools and Health sciences courses, such a way became insufficient for maintaining an appropriate reserve of bodies at Universities, facing ever-increasing demands for bodies [
19]. Furthermore, the development of information technologies has allowed easier identification of bodies, therefore restricting the number of unclaimed bodies addressed to higher education institutions [
19].
In addition, although in many countries, including Brazil, the use of unclaimed bodies remains legal, anatomists do not consider this way ethically appropriate to obtain bodies for teaching and research [
19,
20]. The International Federation of Associations of Anatomists (IFAA) recommended in 2012 that only donated bodies should be used for this purpose [
21]. The use of unclaimed bodies and the bodies of executed persons was considered ethically controversial, since it uses bodies without consent. This practice was also criticized for discriminating against certain minority groups, such as criminals, poor, homeless people and individuals with mental illness [
22,
23].
In this context, an alternative for the maintenance of an anatomical collection at Brazilian universities is to encourage voluntary donations of living donors, an already established strategy in other countries [
19,
24-
27]. The creation of programs with this aim answers to the request of individuals who intend to donate their own bodies to research and studies, providing a legal resource to fulfill this wish [
28,
29]. Brazilian law supports the body donation to teaching and research, for scientific or selfless purposes, since 2002 [
18,
30].
Body donation is accountable for the totality of bodies obtained in Canada, Chile, the United Kingdom, Japan, and New Zealand, whereas in the United States, Uruguay, Portugal, Korea, and South Africa most of the cadavers used in anatomy laboratories are from donation [
23,
27,
31,
32]. In Brazil, there are successful programs in capital cities, such as at the University of São Paulo and at the Federal University of Health Sciences of Porto Alegre (UFCSPA); in the latter institution, the program has been running successfully since 2008 and it currently supplies all the demand in undergraduation [
19,
24]. Organizations working with a private supplier of anatomical material, as described by Wingfield in the United States of America cannot operate in Brazil [
33].
The success of the aforementioned initiatives inspired the creation of a similar program at the Federal University of Juiz de Fora (UFJF). However, the implementation of an innovative body donation program in a city demands special attention regarding culture and uniqueness of its inhabitants, whose profiles are different from the ones found in other countries and places, such as large urban centers. The aim of this paper is to report the experience of the creation of the Program of Voluntary Body Donation for Teaching and Research; Sempre Vivo at UFJF and to describe the challenges encountered in the process and the alternatives to overcome them, as well as the profile of registered donors in the first years of operation.
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Discussion
The Department of Anatomy at UFJF attends nine undergraduate programs in the Health sciences and Biology, with a total of about two thousand students per year, which demands a high availability of bodies and anatomical specimens for study. Literature proofs that the contact with natural specimens and the dissection of bodies contributes heavily to the development of ethical and clinical skills which are essential for healthcare professionals, since this is, possibly, the first contact for most students with death [
1,
2,
6,
7,
17]. This experience promotes reflection regarding death, selflessness, respect and generosity, contributing for the personal development of the students, as well as for a humanized professional formation [
8,
11,
13,
14].
Traditionally, UFJF receives unclaimed bodies, and its availability has been decreasing progressively throughout the years. Considering that the last arrival of unclaimed bodies predates 2010, the alternative to preserve the supply of bodies was to create a program for voluntary body donation. In addition, with the publication of the IFAA guidelines in 2012, body donation has been highly encouraged, mainly for ethical reasons, and programs have emerged in many cities in different countries [
21].
Sempre Vivo started operating in 2014, following the recommendations of good practices towards body donation, in a peculiar scenario. Juiz de Fora differs from the capital cities and large urban centers, where the main bequest programs in operation in Brazil are located. In this context, it was essential for the team to elaborate an outreach project to raise awareness among potential donors. The Department of Anatomy considers the program satisfactory up to this level and believes that body donation is a feasible alternative and, at the moment, it is the main source for the maintenance of the reserve of bodies at the Institution.
The relevance of donation programs to supply demands of bodies and anatomical specimens to teaching institutions in different countries and regions worldwide is widely evident and validates the current findings [
13,
27,
44-
46]. At the University of Otago, in New Zealand, the bequest program of the School of Medical Science has been active since 1943, with more than 140 annual registers in the last decades, and also with an approximate reception of 3,000 bodies [
45]. In Poland, the donation program at the University of Silesia, in Katowice, counts with approximately 1,250 registered donors since its creation, in 2003 [
44]. At the University of Bologna, in Italy, the authors observed an increase from 12 to 431 living donors between the creation of its bequest program in 2013 and the first trimester of 2020 [
13]. The number of body donations in Korea increased from 7 to 128 annually at the Yonsei University College of Medicine between 1992 and 2019, reaching a total of 2415 donors [
27]. In Brazil, the UFCSPA used to receive about 5 donors registers a year. After the creation of a body donation program, in 2008, this number increased to more than 29 annual registers [
19].
Table 2 summarizes the donation programs discussed and shows that the number of annual donor registers is higher in older bequest programs and in more populated regions. In Brazil, UFSCPA's body donation program has three times more annual donor registers than
Sempre Vivo, but the population of the city of Porto Alegre is around three times larger. In addition, the UFSCPA's program has been in operation for approximately 12 years [
34,
19].
Table 2
Summary of the body donation programs discussed above, highlighting the year of foundation and the number of registered donors per year
University (country) |
Foundation of the bequest program |
Donor registers (yr) |
University of Otago (New Zealand) |
1943 |
>140 |
Yonsei University College of Medicine (Korea) |
1992 |
>128 |
University of Silesia (Poland) |
2003 |
>113 |
University of Bologna (Italy) |
2013 |
>61 |
Federal University of Health Sciences of Porto Alegre (Brazil) |
2008 |
>29 |
Federal University of Juiz de Fora (Brazil) |
2014 |
>10 |

On the other hand, unclaimed bodies are still widely used worldwide, including in Brazil. In some countries, it remains the exclusive source of bodies for teaching and research [
23]. Since this practice was considered ethically controversial, many anatomists find themselves in a complicated work situation. New discussions addressing this current condition need to occur in the international scientific community, considering the limitations of different realities [
20,
41].
Regarding the profile of the donors registered on
Sempre Vivo, the females are predominant: they correspond to 70.3%, which is higher than the sex difference observed in Brazil, where 51.7% of its inhabitants are female [
34]. Similar results were found by Bajor et al. [
44] in Poland, by Cornwall et al. [
25] in New Zealand, and by Orsini et al. [
13] in Italy. In addition, Cornwall et al. [
36] showed that in countries like South Africa, Ireland, and New Zealand, female correspond to most of the donors, but they do not differ from the rates that characterize the general population. On the other hand, some studies have registered a very similar proportion between sexs of the donors [
42,
47].
The average age of registered donors is approximately 57 years old, which agrees with other studies that present similar results. Orsini et al. [
13] found an average age of 59.1 years among registered donors in the University of Bologna, in Italy. In Ireland, the average age registered was around 60 years old; according to the authors, the use of the internet as a means of publicizing the body donation program resulted in a much higher number of younger donors [
36]. An important means of accessing
Sempre Vivo is the website of the Department of Anatomy, which may partly justify the average age among registered profiles. On the other hand, Park et al. [
27] have found a gradual increase in the average age for body donation over 28 years of their bequest program. Jedrzejewski and Ritter [
47] found a higher average age, around 82 years, in Rhode Island, USA, which may be associated with a higher life expectancy of the local population [
48]. Several studies around the world have also identified a higher average age among donors [
25,
27,
42-
44]. According to da Rocha et al. [
37], this age characteristic might be related to the fact that people over 60 years of age are more likely to consider death and the fate of their bodies.
In addition, the fact that the main way to know
Sempre Vivo is through other donors might be associated with efficient and clarifying service to the potential donors and the credibility of the program. The body donation to teaching and research institutions must be carried out according to ethical principles. Transparency in the procedures for donating and handling the body is important for the donor safety, increasing the society contribution and the number of donations. Informed consent and recommendations on the non-commercialization of the body are principles that should guide the body donation [
8,
20,
21,
27].
Regarding the level of study among donors, previous studies have shown that individuals associated with donation programs presented a level of formal education of approximately 12 years of study [
36,
42,
44]. Most donors of
Sempre Vivo presented 12 years or more of formal instruction, supporting this information. This fact might be related to the quality and source of information that the people with a higher education can have access to. In Turkey, the amount of donated bodies meets the need of educational institutions in cities with high educational levels [
26]. Furthermore, several researchers reported that body donors tend to have higher educational levels than respective populations [
36,
42,
49,
50]. A study performed in Spain with 2,000 people analyzed the factors that would be associated with organ donation, a very similar scenario. The results have demonstrated that media like television and radio are the ones which allow a wider spread of the information to the population, but a superficial and simplistic approach to the theme does not favor the numbers of people favorable to the donations. In contrast, people with a higher level of education are also exposed to the theme within their institutions, in which organ donation is approached at a deeper level and they are given space for asking questions, which favors acceptance [
51]. It is plausible that these considerations can also be applied to body donation, which reinforces the importance of informing donors, and that is already developed in
Sempre Vivo. Aiming at reaching the academic and scientific community, educational lectures about body donation are performed for every anatomy student, and the program is published in scientific events, locally and nationally.
In addition, regarding the current job situation of registered donors, the results of
Sempre Vivo are similar to those found by Bajor et al. [
44] in Poland, where 68% of all the people registered in the donation program are also retired. Alternatively, McClea and Stringer [
43] demonstrated that, in New Zealand, even though the majority of the population is above 60 years old, there is an increasing participation of donors in the active labor market. This characteristic might be associated with an increase of life expectancy around the world in the last decades, as well as with the need of adjustment of retirement systems in several countries, lengthening the workers’ activities [
43,
52].
Furthermore, the income profile of
Sempre Vivo donors is similar to the Brazilian population profile of income, according to data from the Brazilian Institute of Geography and Statistics: 42.5% earn up to US $600.00 monthly, 44.5% between US $600.00 and $ 2,000.00, and 13.0% more than US $2,000.00 per month [
34]. This profile is corroborated by da Rocha et al. [
37] in a major urban center in Brazil. Researchers in other developing countries found a similar result. In Turkey, for instance, the majority of registered donors (39.3%) had a monthly income between 1,000 and 2,000 TL (approximately US $127–254), while in Thailand 42.8% of the donors had a monthly income between 10,000 and 30,000 Baht (approximately US $320–960) [
50,
53].
Regarding religion, the current program has noticed that one in two donors to
Sempre Vivo is a declared Spiritist. Therefore, Spiritism is the most present religious belief among donors, which differs from the national religious profile. According to the 2010 census, only 2% of the Brazilian population declared themselves to be Spiritists, while in Juiz de Fora, considered as a reference of this religious belief, 5.4% of the citizens are adept to Spiritism. In addition, da Rocha et al. [
37] assessed the donor profile of a specific region of Brazil where Catholicism predominates with 68.4% of the population and only 3.6% is Spiritualist, but 30.2% of the donors sample evaluated declared themselves Spiritualist, reinforcing the findings of this study. According to Gunderman [
54], donating your own body for research and teaching shows great selflessness for the benefit of others. In this context, it is possible then that Spiritism is associated with a higher tendency of body donation, for it is a reincarnationist doctrine that preaches selflessness, dissociation of the body and detachment of the matter [
46,
55]. Other doctrines that also preach the existence of life after death and that the body is only a temporary shelter to the spirit also favor voluntary body donation. In countries where Buddhism is predominant, for example, programs refuse bodies for not having any more physical space [
46]. In Korea, the contact of its citizens with the Western culture has reduced the dominance of Confucianism, in which it rejects any form of unnatural disturbance to the body, increasing the number of donors [
27,
55]. In Turkey, an interesting finding of Gürses et al. [
53] was that religion is both a positive and negative motivational factor, and they argued that given Turkey´s different and diverse religions, differences at the donor´s profile are also expected.
However, while some religions such as Spiritism make body donation desirable and comfortable for their followers, this decision does not need to be considered contrary to other types of faith and religious beliefs [
46,
55]. The information can demystify the process, show its importance and increase the number of donors from different religions. This reinforces the need for actions to clarify and raise awareness among the population, which was decisive for the
Sempre Vivo team to elaborate an outreach project with this objective [
8]. Although Juiz de Fora has a larger Spiritist population than other locations in Brazil, this percentage is still very small compared to other religions [
34].
The collected data suggest that the prevailing profile among donors for
Sempre Vivo is a woman, with higher education, with an average age around of 60 years, and also a declared Spiritist. Some of these traits are not usually found in other body donation programs, and this highlights the fact that the donor profile varies according to their place of application [
36,
42-
44]. The city of Juiz de Fora presents unique characteristics that might have influenced the implementation and operation of the
Sempre Vivo program.
The challenges of creating a body donation program are numerous, but the results are worth it. Some important suggestions can help the process. First, to form a team of human anatomy professors and students who value the body donation for teaching and research. Second, to deeply study the ethical principles involved in body donation; thirdly, to access all information about the legislation that regulates the body donation at the location of the program creation; fourthly, to take advantage of the experience of bequest programs already operating in the host country and abroad; fifthly, to develop a population raising-awareness strategy based on the specific characteristics of their citizens. Furthermore, once the program has been created, it is worthwhile, as soon as possible, to profile the donor and modify the publicization strategy if necessary.
Lastly, there are some limitations in this study, which include the currently short running time of the program and its application in a single university, which restricts the sample numerically. Broader studies, with a larger longitudinal reach, may complement the data and allow this experience to be more faithfully foretold in other contexts. However, in the UFJF scenario, Sempre Vivo is considered an adequate and promising program according to the academic community and the Institution's administration. In the future, it may be the exclusive source of the University reserve of bodies and anatomical specimens.
In conclusion, considering that the UFJF Department of Anatomy has not received unclaimed bodies for ten years and Sempre Vivo has allowed the arrival of seven bodies in six years, body donation represents a viable and ethically desirable alternative for maintaining the supply of anatomical specimens at higher education institutions.
The description of the creation and the publicizing of Sempre Vivo, the challenges encountered in the process and the alternatives to overcome them, as well as the donors’ profile, may encourage and facilitate the foundation of new similar programs in other teaching and research Institutions, both in Brazil and abroad.
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