Measuring Defocus Curves of Monofocal, Multifocal and Extended Depth-of-focus Intraocular Lenses Using Optical Bench Test

Yong Ho Koo; Chang Su Lee; Jin Soo Kim; Min Chul Shin; Eun Chul Kim; Man Soo Kim; Ho Sik Hwang

doi:10.3341/jkos.2020.61.2.153

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Koo, Lee, Kim, Shin, Kim, Kim, and Hwang: Measuring Defocus Curves of Monofocal, Multifocal and Extended Depth-of-focus Intraocular Lenses Using Optical Bench Test

Original Article

Journal of the Korean Ophthalmological Society 2020; 61(2): 153-158.

Published online: 18 February 2020

DOI: https://doi.org/10.3341/jkos.2020.61.2.153

Measuring Defocus Curves of Monofocal, Multifocal and Extended Depth-of-focus Intraocular Lenses Using Optical Bench Test

Yong Ho Koo, MD¹, Chang Su Lee, PhD², Jin Soo Kim, MD¹, Min Chul Shin, MD, PhD¹, Eun Chul Kim, MD, PhD³, Man Soo Kim, MD, PhD⁴, Ho Sik Hwang, MD, PhD⁵

¹Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.

²Department of Electronic Engineering, College of Engineering, The University of Suwon, Hwaseong, Korea.

³Department of Ophthalmology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.

⁴Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

⁵Department of Ophthalmology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Address reprint requests to Ho Sik Hwang, MD, PhD. Department of Ophthalmology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #10 63-ro, Yeongdeungpo-gu, Seoul 07345, Korea. Tel: 82-2-3779-1025, Fax: 82-2-761-6869, huanghs@hanmail.net

Received 23 September 2019 Revised 14 October 2019 Accepted 22 January 2020

The Korean Ophthalmological Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To determine the through-focus optical bench test performance of monofocal, bifocal, and extended depth-of-focus intraocular lenses (IOLs), and to measure their defocus curves.

Methods

A model eye was placed on an optical bench to test three different IOLs (TECNIS ZXR00, ZMB00, and ZCB00; Abbott Medical Optics, Santa Ana, CA, USA). The focus was changed by inserting trial lenses from +1.00 diopters to −4.00 diopters, in increments of +0.25 diopters. The 1951 United States Air Force Resolution chart was used to determine the quality of the images. The degree of similarity with reference images was given by the cross-correlation coefficient, and defocus curves were drawn and compared.

Results

Bifocal IOLs showed lower image quality with the addition of minus diopter trial lenses, but showed good image quality at near distance. Bifocal IOLs also showed a ‘double peak’ in their defocus curve. Monofocal IOLs showed a lower image quality and cross-correlation coefficient with addition of lower-diopter trial lenses. The extended depth of focus IOLs showed a single peak in their defocus curve, but had a wider range of diopters and better image quality than monofocal IOLs.

Conclusions

Bifocal IOLs showed a double peak defocus curve, and extended depth of focus IOLs showed a wider diopter range and better image quality than monofocal IOLs.

Keywords: Bifocal, Defocus curve, Extended depth of focus, Optical bench test

Figures and Tables

Figure 1

Schematic diagram of optical bench system. Optical bench system is composed of resolution target, artificial pupil, trial lens, model eye and complementary metal-oxide-semiconductor camera. IOL = intraocular lens; CMOS = complementary metal oxide semiconductor.

Figure 2

Photo of optical bench system. Optical bench system is composed of resolution target, artificial pupil, trial lens, model eye and complementary metal-oxide-semiconductor camera.

Figure 3

Captured images of 1951 United States Air Force resolution test chart using bifocal intraocular lens (TECNIS® ZKB00, Abbott Medical Optics, Inc., Santa Ana, CA, USA). Minus diopter represents near distance.

Figure 4

Captured images of 1951 United States Air Force resolution test chart using monofocal (TECNIS® ZCB00, Abbott Medical Optics, Inc., Santa Ana, CA, USA), bifocal (TECNIS® ZKB00, Abbott Medical Optics, Inc.) and extended depth of focus intraocular lens (TECNIS® Symfony ZXR00, Abbott Medical Optics, Inc.). EDOF = extended depth of focus.

Figure 5

Through-focus correlation coefficients of the three different intraocular lenses. Bifocal intraocular lens (TECNIS® ZKB00, Abbott Medical Optics, Inc., Santa Ana, CA, USA) showed double peak appearance but monofocal (TECNIS® ZCB00, Abbott Medical Optics, Inc.) and extended depth of focus showed single peak appearance. Extended depth of focus intraocular lens (TECNIS® Symfony ZXR00, Abbott Medical Optics, Inc.) had a wider range of diopters with a cross-correlation coefficient of 0.7 or greater than monofocal intraocular lens. EDOF = extended depth of focus.

Table 1

Intraocular lens specifications

IOL = intraocular lens; NA = not applicable.

Notes

^{Conflicts of Interest} The authors have no conflicts to disclose.

This study was Supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI17C0659), Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education, Republic of Korea (No. 2017R1A1A2A10000681), and the Sodam Scholarship Foundation of Busan Sungmo Eye Hospital.

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