Journal List > Allergy Asthma Respir Dis > v.8(1) > 1141945

Kim, Hahm, Kim, Koo, and Jung: Identification of pulmonary paragonimiasis using Ziehl-Neelsen stain

Abstract

Pulmonary paragonimiasis and tuberculosis are endemic in Asia, South America, and Africa. However, differential diagnosis among the diseases is difficult because they present with similar clinical symptoms and diagnostic features. Here, we report a case of pulmonary paragonimiasis that was identified using Ziehl-Neelsen stain after initially being assessed for pulmonary tuberculosis. Following anti-Paragonimus chemotherapy, the patient's symptoms, laboratory test results, and lung lesions improved. Thus, the identification of Paragonimus westermani using Ziehl-Neelsen stain can be considered in the diagnosis.

Figures and Tables

Fig. 1

A sputum smear slide with Ziehl-Neelsen stain showed a reddish to brownish colored egg suspected of Paragonimus westermani. Magnification was 1,000× using oil immersion.

aard-8-36-g001
Fig. 2

(A) The initial chest X-ray in lateral decubitus position shows a significant amount of left pleural effusion (arrows). (B) Chest X-ray obtained 1 month later shows that the pleural effusion is resolved.

aard-8-36-g002
Fig. 3

Axial computed tomography (CT) scans reveal a focal area of consolidation containing tiny nodules in the upper left lobe (arrow) at the pulmonary window setting (A) and left pleural effusion (arrow) at the mediastinal window setting (C). (B, D) CT images obtained during the 3-month follow-up examination reveal improved lung lesions.

aard-8-36-g003

References

1. Kagawa FT. Pulmonary paragonimiasis. Semin Respir Infect. 1997; 12:149–158.
pmid
2. Slesak G, Inthalad S, Basy P, Keomanivong D, Phoutsavath O, Khampoui S, et al. Ziehl-Neelsen staining technique can diagnose paragonimiasis. PLoS Negl Trop Dis. 2011; 5:e1048.
crossref
3. Sim YS, Lee JH, Hong SC, Chang JH, Kang SR, Yang HJ, et al. Paragonimus westermani found in the tip of a little finger. Intern Med. 2010; 49:1645–1648.
crossref pmid
4. Jeon K, Koh WJ, Kim H, Kwon OJ, Kim TS, Lee KS, et al. Clinical features of recently diagnosed pulmonary paragonimiasis in Korea. Chest. 2005; 128:1423–1430.
crossref pmid
5. Kim TS, Han J, Shim SS, Jeon K, Koh WJ, Lee I, et al. Pleuropulmonary paragonimiasis: CT findings in 31 patients. AJR Am J Roentgenol. 2005; 185:616–621.
crossref pmid
6. Sadun EH, Buck AA. Paragonimiasis in South Korea--immunodiagnostic, epidemiologic, clinical, roentgenologic and therapeutic studies. Am J Trop Med Hyg. 1960; 9:562–599.
pmid
7. Diaz JH. Paragonimiasis acquired in the United States: native and nonnative species. Clin Microbiol Rev. 2013; 26:493–504.
crossref pmid pmc
8. Im JG, Whang HY, Kim WS, Han MC, Shim YS, Cho SY. Pleuropulmonary paragonimiasis: radiologic findings in 71 patients. AJR Am J Roentgenol. 1992; 159:39–43.
crossref pmid
9. Hwang KE, Song HY, Jung JW, Oh SJ, Yoon KH, Park DS, et al. Pleural fluid characteristics of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis. Korean J Intern Med. 2015; 30:56–61.
crossref pmid
10. Im SH, Shin SH, Song MJ, Kim JW, Kim SJ. A case of Paragonimiasis in the abdominal subcutaneous tissue with pleural effusion. Tuberc Respir Dis. 2004; 56:550–554.
crossref
11. Cho SY, Lee DK, Kang SY, Kim SI. An epidemiological study of human paragonimiasis by means of micro-ELISA. Kisaengchunghak Chapchi. 1983; 21:246–256.
crossref pmid
12. Kuzucu A. Parasitic diseases of the respiratory tract. Curr Opin Pulm Med. 2006; 12:212–221.
crossref pmid
TOOLS
ORCID iDs

Woo Jin Jung
https://orcid.org/0000-0003-4519-1042

Similar articles