Metabolic Surgery and Diabetes Mellitus: Its Effects and Side Effects

Mee Kyoung Kim

doi:10.4093/jkd.2019.20.4.205

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Kim: Metabolic Surgery and Diabetes Mellitus: Its Effects and Side Effects

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The Journal of Korean Diabetes 2019; 20(4): 205-209.

Published online: 31 December 2019

DOI: https://doi.org/10.4093/jkd.2019.20.4.205

Metabolic Surgery and Diabetes Mellitus: Its Effects and Side Effects

Mee Kyoung Kim

Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Corresponding author: Mee Kyoung Kim. Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 10 63-ro, Yeongdeungpo-gu, Seoul 07345, Korea, makung@catholic.ac.kr

Received 25 October 2019 Accepted 30 October 2019

Korean Diabetes Association

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Recent studies have shown that metabolic surgery can lead to the remission of diabetes mellitus (DM) in a large portion of patients with both type 2 DM and morbid obesity. Metabolic surgery may be considered for glycemic control and weight loss in obese patients with type 2 DM. The most commonly performed bariatric surgeries are sleeve gastrectomy and Roux-en-Y gastric bypass. The effect of metabolic surgery, especially Roux-en-Y gastric bypass, is thought to be caused by mechanisms other than weight loss. Increased insulin secretion associated with altered gut hormones might play a role in this improvement. After metabolic surgery, glucose, lipids, and blood pressure are greatly improved, but not all patients with type 2 DM who undergo metabolic surgery achieve DM remission.

Keywords: Bariatric surgery, Diabetes mellitus, Korea

Figures and Tables

Fig. 1

Types of bariatric surgery procedures.

Fig. 2

Trends in primary metabolic surgical procedures.

AGB, adjustable gastric banding; RYGB, Roux-en-Y gastric bypass; SG, sleeve gastrectomy; G-plication, gastric plication; D-switch, duodenal switch; OAGB, one anastomosis gastric bypass; SGJB, sleeve gastrectomy with jejunal bypass.

References

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