Abstract
Purpose
To present the first report describing lesions of osteoma cutis on the upper eyelid and medial canthus.
Case summary
A 4-year-old female complained of a right upper eyelid mass. The examination showed a well-delineated, mild bluish-colored, hard mass over the upper eyelid and the medial canthus measuring 10 × 10 mm and 2 × 2 mm. During the cutaneous examination, her forearm, left shin, right dorsum of the foot, neck, and abdominal wall also showed well-delineated, mild bluish-colored, immobile hard masses, similar to the upper eyelid mass. A right upper eyelid and medial canthus mass excision was performed and a biopsy specimen was collected. Hematoxyline and eosin staining showed a mature bone in the dermis with spicules of bone and osteoblasts. She was finally diagnosed with osteoma cutis on the upper eyelid and the medial canthus.
Figures and Tables
Figure 1
Anterior segment photographs of the mass and clinical photograph of patient at inital presentation. (A) There was well marginated, mild bluish-colored, hard mass was seen on right eyelid (arrow) and medial canthus (arrowhead). (B) The child showed rounded chubby face and flat nose. Informed consent was obtained from the study participant.
![jkos-60-1290-g001](/upload/SynapseData/ArticleImage/0035jkos/jkos-60-1290-g001.jpg)
Figure 2
Orbit computed tomography scan with enhancement image. That showed bone density well-defined lesions in right eyelid (arrow) and medial cahthus (arrowhead). Axial view.
![jkos-60-1290-g002](/upload/SynapseData/ArticleImage/0035jkos/jkos-60-1290-g002.jpg)
Figure 3
Overview dissection of biopsy of eyelid mass. Histopathology of the tissue biopsy demonstrated spicules of bone (red arrow) in the dermis and subcutaneous tissue (haematoxylin and eosin stain, ×12.5). Hair follicle (red arrowhead) and eccrine sweat gland (black arrowhead) are shown in dermis.
![jkos-60-1290-g003](/upload/SynapseData/ArticleImage/0035jkos/jkos-60-1290-g003.jpg)
Notes
References
1. Roth S, Stowell RE, Helwige B. Cutaneous ossification. Report of 120 cases and review of the literature. Arch Pathol. 1963; 76:44–54.
2. Bang HD, Kim KH, Cho KH. A case of primary osteoma cutis. Annals of Dermatology. 1996; 8:121–124.
3. Mast AM, Hansen R. Multiple papules on the elbows. Arch Dermatol. 1997; 133:780.
4. Boyd AS, King LE Jr. Basal cell carcinoma with ossification. J Am Acad Dermatol. 1998; 38:906–910.
5. Gupta SR, Cogen MS, Metz TH Jr. Congenital osteoma cutis of the lateral canthus. J AAPOS. 2009; 13:410–412.
6. Fazeli P, Harvell J, Jacobs MB. Osteoma cutis (cutaneous ossification). West J Med. 1999; 171:243–245.
7. Monroe AB, Burgdorf WH, Sheward S. Platelike cutaneous osteoma. J Am Acad Dermatol. 1987; 16(2 Pt 2):481–484.
8. Jung JN, Cho YH, Seo JH, et al. Osteoma cutis in Albright's hereditary osteodystrophy. Korean J Dermatol. 2004; 42:493.
9. Kapoor S, Gogia S, Paul R, Banerjee S. Albright’s hereditary osteodystrophy. Indian J Pediatr. 2006; 73:153–156.
10. Prendiville JS, Lucky AW, Mallory SB, et al. Osteoma cutis as a presenting sign of pseudohypoparathyroidism. Pediatr Dermatol. 1992; 9:11–18.
11. Ryu DJ, Oh SH, Han EC, et al. A case of osteoma cutis, a diagnostic clue for albright's hereditary osteodystrophy. Korean J Dermatol. 2009; 47:435–438.
12. Aguinaga F, Trope B, Piñeiro-Maceira J, Ramos-e-Silva M. Miliary osteoma cutis: a case report. Case Reports in Dermatological Medicine. 2014; 2014:347829.
13. Hernandez-Martin A, Perez-Mies B, Torrelo A. Congenital Platelike Osteoma Cutis in an Infant. Pediatr Dermatol. 2009; 26:479–481.
14. Moreira Amorim G, Mastrangelo Marinho Falcão EMMF, Carvalho Quintella D, et al. Primary isolated osteoma cutis of the face. Dermatol Online J. 2017; 23:13030/qt4zz8d3tm.
15. Sanmartin O, Alegre V, Martinez-Aparicio A, et al. Congenital platelike osteoma cutis: case report and review of the literature. Pediatr Dermatol. 1993; 10:182–186.