Authors experienced two cases of osteoarthropathy due to mediastinal tumor, which are reported with a reviewof the literature. A case was 59 years old man, who complained chest discomfortness, coughing, dyspnea andclubbing fingers. The other was 39 years old man, who complained arthralgia, clubbing of digits and pain in theleft medial clavicular area. Their family histories were not contributory. The radiologic findings of the chestshowed tumorous mass in the mediastinum. Examination of the extremities showed periosteal reaction andsubperiosteal proliferation along the long bones and digits. Distal phalanges revealed clubbing without bonechanges.