The diagnostic roentgenologic osseous changes in congenital sy have been most definitely defined by McLean in1931. The high indicence of skeletal involvement in young syphilitic infants has been proved beyond question andthe roentgenographic features of these lesions are well known. The material here reviewed consisted of 5 infantsof congenital syphilis under one year age. Stated briefly, the signs readly recognized and of chief diagnosticimportance are; 1. Well defined saw-tooth (zig-zag) metaphysis. 2. Single thickened transverse lines of increaseddensity at the ends of shafts. 3. Transverse zone of diminished density in the ends of shafts plus prallelthickened transverse increased density. 4. Radiolucent density occupying the ends of the shafts. 5. Bilateralsymmetical osteomyelitis of proximal medial aspects of the long bone (Wimberger's sign) 6. Localized periostealclocking occuring in the shafts of long bone. The study of 3 case of congenital syphilis there were 4 cases inwhich the typical roentgenographic evidence of bone changes were shown. Roentgenographic skeletal lesion ofcongenital syphilis are simulated in wide variety of condition in young infants. It is only by the clinical,serologic and roentgenologic observation that the knowledge of congenital syphilis will be furthered.