Axial CT may detect a lesion, but accurate localization and evaluation of extent maybe difficult. Multiple plane CT provides three-dimensional anatomy and improved localization and extent of lesions. Recent technical advances in CT have enabled evaluation of lesion in multiple planes. Direct coronal scans have some limitations such as discomfort positioning, additional radiation exposure and inability of reconstruction of sagittal image. The SCI shoftward package allows to display sagittal or coronal images derived from a series of axial CT scans. This study reviews some of our experiences in computer reconstructed SCI of variety of lesions within human bodyand attempts to illustrated the value of it. The SCI enables to provide the physician with all possible information relating a particular lesion to surrounding anatomic landmarks such as exact size and location of thelesion as well as increased specificity of disgnosis without the former's limitations. It is useful in evaluating lesions of the skull base, apex and sellar region, determining if a lesion is intra-or extraventricular and intra-or extraaxial, and in distinguishing between supra- and infratentorial lesions. It is also help to determine approach of operation, to define portals of deep radiation therapy and chemotherapy and to evaluate the effect oftreatment. Therefore, it is anticipated that referring physicians, especially surgeons, may benefit greatly fromthe availability of these images although they may also be diagnostically useful to radiologist.