Multiple Progressive Intracranial Arterial Occlusion (MPIAO) is a rare cerebrovascular disease and itsclinical diagnosis is nearly impossible and diagnosis depends upon neuroradiological studies. Amongneuroradiological studies, cerebral angiography is mandatory in diagnosis and in localization of stenotic orocclusive vascular lesion, visualization of collateral channels and aid the surgical management. Five cases MPIAO which were proved by cerebral angiography at Capital Armed Forces General Hospital during last 5 years arepresented, with analysis of radiological findings as well as clinical assessment. The resuls are as follows; 1. Age distribution ranges from 23 to 46. For cases are male and one female. 2. Cardinal clinical symptoms areheadache and vomiting, and neurological manifestations are hemiplegia and speech disturbance. 3. All cases showthe characteristic angiographic findings of MPIAO which are occlusion or stenosis at the distal internal carotidartery, proximal part of anterior and middle cerebral arteries with fine collateral network in basal gangliaarea,leptomenigneal anastomosis and transdural extenral- internal carotid ananstomoses. The major region ofocclusion or stenosis is first portion of anterior and middle cerebral arteries. In one case, the lesion is seenin cervical portion of internal carotid artery. There is no evidence of occulusion or stenosis in vertebralangiogram. 4. In 2 cases, CT was done. One case shows the findings of cerebral infarction and the otherintracerebral hematoma.