Authors recommend ultrasound be used as a screening test in evaluation of suspected liver masses. Besides itsspeedness, wide availability, easy scheduling and lack of radiation hazard, ultrasound is higher in sensitivity,better in characterization of a lesion, and better in staging of a cancer than radionuclide scanning Ultrasoundcould be used to delineated pedunculated hepatoma and anatomic variations, to differentiate intahepatic fromextrahepatic lesions, and to evaluate multiple organs simultaneously, while radionuclide scanning can not affordany benefit in these aspects. In addition, ultrasound could be used as a guide for diagnostic or therapeurticaspiration.