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Noh, Park, and Koh: Primary Amyloidosis Localized to the Conjunctiva
Case Report

Journal of the Korean Ophthalmological Society 2019; 60(11): 1117-1120.

Published online: 19 November 2019

DOI: https://doi.org/10.3341/jkos.2019.60.11.1117

Primary Amyloidosis Localized to the Conjunctiva

Ha Jeong Noh, MD, Beom Chan Park, MD, Jae Woong Koh, MD, PhD

Department of Ophthalmology, Chosun University College of Medicine, Gwangju, Korea.

Address reprint requests to Jae Woong Koh, MD, PhD. Department of Ophthalmology, Chosun University Hospital, #365 Pilmun-daero, Dong-gu, Gwang-ju 61453, Korea. Tel: 82-62-220-3190, Fax: 82-62-225-9839, ophkoh@hanmail.net

Received 2 May 2019       Revised 26 June 2019       Accepted 23 October 2019

©2019 The Korean Ophthalmological Society

The Korean Ophthalmological Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report a case of primary amyloidosis localized to the conjunctiva.

Case summary

A 19-year-old male with a conjunctival mass and foreign body sensations in the right eye transferred from another hospital. A 0.5 × 2.5 cm reddish mass was present in the medial canthus of the right conjunctiva with no other clinically specific signs. Surgical excisional biopsy was performed. Histological examination showed amyloid deposition. There was no other orbital involvement apart from the conjunctiva. Abnormalities were not found in the systemic examination.

Conclusions

We report a case of primary amyloidosis localized to the conjunctiva.

Keywords: Amyloidosis, Biopsy, Conjunctival neoplasm

Figures and Tables

Figure 1

Slit-lamp photograph on the first visit. A reddish diffuse protruding mass in the medial canthal conjunctiva in the right eye (arrow) (A). Surgical excisional biopsy was performed, and the specimen size was 0.5 × 2.5 × 0.2 cm (B).

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Figure 2

Histological features of the conjunctival mass. A hematoxylin and eosin (H&E)-stained section showed amorphous, homogenous, eosinophilic material composed of amyloid (arrows). (A) H&E staining (×200). (B) H&E staining (×400).

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Figure 3

Histological features of the conjunctival mass. A Congo-red-stained section shows orange colored stained amyloid deposits (arrows). (A) Congo red staining (×100). (B) Congo red staining (×400).

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Figure 4

Slit-lamp photograph at the 6 months after operation. The mass was completely removed, with no recurrence.

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Notes

The present study was supported by grants from the Clinical Medicine Research Institute at Chosun University Hospital, 2015.

Conflicts of Interest The authors have no conflicts to disclose.

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