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Hyo-Joon Yang
, In-Gu Do1, Chang Hak Yoo2
, In-Gu Do1, Chang Hak Yoo2
Figures and Tables
 | Fig. 1Esophagogastroduodenoscopy findings. A large subepithelial tumor with a normal overlying epithelium larger than 5 cm in size occupying cardia and mid to high body lesser curvature side.
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 | Fig. 2Abdominal computed tomography (CT) and positron emission tomography (PET). CT images show (A) a 6.7 cm sized large mass arising from the left side of the gastric body (arrow) and (B) left paraaortic lymph node enlargement (arrow). PET images show increased 18F-fluorodeoxyglucose uptake in (C) left gastric mass and (D) left paraaortic lymph node.
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 | Fig. 3Pathology findings of a fine needle aspiration/biopsy specimen. (A) Microscopic findings of the specimen show poorly differentiated small epithelioid cell nests (H&E, ×20). (B) Immunohistochemical staining findings were compatible with the diagnosis of a poorly differentiated carcinoma (upper left: CK [AE1/AE3], ×20; upper right: CD 56, ×20; lower left: LCA, ×20; lower right: Vimentin, ×20).
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 | Fig. 4Pathology findings of a surgical specimen. (A) Gross appearance of the resected stomach shows a gray white to pale yellowish solid mass involving the submucosa to serosa. The mucosa surface is intact. (B) H&E stain revealed intact mucosa and poorly differentiated small epithelioid tumor cells involving the submucosa to serosa (upper left: H&E, ×4). Tumor cells are positive for CK (AE1/AE3) and negative for LCA, CD56, and vimentin. Based on the H&E and immunohistochemistry findings, tumor is consistent with a poorly differentiated adenocarcinoma (upper right: CK [AE1/AE3], ×4; lower left: LCA, ×4; lower right: CD 56, ×4).
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References
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3. Ohara N, Tominaga O, Uchiyama M, Nakano H. A case of advanced gastric cancer resembling submucosal tumor of the stomach. Jpn J Clin Oncol. 1997; 27:423–426.
4. Standards of Practice Committee. Faulx AL, Kothari S, et al. The role of endoscopy in subepithelial lesions of the GI tract. Gastrointest Endosc. 2017; 85:1117–1132.
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