Early diagnosis of hepatocellular carcinoma(hepatoma) along with surgical resection is the most appropriate therapeutic modality. For this purpose, there have been many reports concering the diagnostic value of Lipiodol-CT scan. The authors selected 45 patients with hepatoma during the period of Feb. 1986 to Jan. 1988 who received a conventional CT scan, hepatic angiography and a Lipiodol-CT scan. The results were as follows: 1. There was nostatistical significance between serum AFP level and mass size, morphology and amount of necrosis. 2. Tumornecrosis was observed in a single massive and multinodular type when the tumor size exceeded 5cm. 3. Pattern II onLipiodol-CT, homogenous accumulation of Lipiodol except for the area of innner necrosis, was most frequnetly demonstrated, which means that tumor mass with hypervascularity and increased blood flow will attract Lipiodol better. 4. Lipiodol-CT was superior to conventional CT in detecting small, daughter nodules. 5. When Lipiodol had accumlated well within the tumor, non-change and decrease of the serum AFP level after Lipiodol injection occurrred in 90% of cases, which suggested clinical significance of therapeutic process.