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Abstract
There has been onJ.y one report that water-soluble contrast media containing iodine and used in conventional X-ray radiography reduce T1- and T2-relaxation times. We evaluated the relationship between signal intensity (relatives ignal intensity to normal saline) and T2-relaxation time of MRI and the concentration of 3 water-soluble contrast media [meglumine ioxithalamate (Telebrix 30®).iopromide (Ultravist 300®j, iotrolan (Isovist 300® 1 through the phantom study, using both 2.0T and 0.5T MR units.
We found that the signal intensity increased significantly on the T1-weighted images as the concentration of contrast media increased. The degree of the increase was larger on 0.5T MR than on 2.0T MR. The signal intensity on proton density image showed no significant difference at various concentrations. However, there were significant decreases of both signal intensity on the T2-weighted images and T2-relaxation time as the concentration of contrast media increased, which was more prominent on 2.0T MR than 0.5T MR. Between the contrast media of the same concentration, there was no significant difference in signal intensity and T2-relaxation time.
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