Relief of Cancer Pain in Patients with Pancreatic Cancer

Jung Wan Choe; Jong Jin Hyun

doi:10.4166/kjg.2019.74.2.81

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Choe and Hyun: Relief of Cancer Pain in Patients with Pancreatic Cancer

Special Review

Supportive and Palliative Care of Pancreatic Cancer

The Korean Journal of Gastroenterology 2019; 74(2): 81-86.

Published online: 27 August 2019

DOI: https://doi.org/10.4166/kjg.2019.74.2.81

Relief of Cancer Pain in Patients with Pancreatic Cancer

Jung Wan Choe, Jong Jin Hyun

Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea.

Correspondence to: Jong Jin Hyun, Department of Internal Medicine, Korea University Ansan Hospital, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, Korea. Tel: +82-31-412-4856, Fax: +82-31-412-5582, sean4h@korea.ac.kr

Received 12 July 2019 Revised 23 July 2019 Accepted 23 July 2019

Korean Society of Gastroenterology

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Pancreatic cancer is a dismal disease with a poor prognosis and is one of the most painful malignancies. Therefore, adequate pain control is essential to improving the patient's quality of life. Pain in pancreatic cancer has complex pathophysiologic mechanisms and different characteristics. The choice of pain management modalities should be individualized depending on the pain characteristics using a multidisciplinary approach. The treatment options available include medical treatment, chemotherapy, celiac plexus/ganglion neurolysis, radiotherapy, and endoscopic technique. This review discusses the medical and interventional options, leading to optimal pain management in patients with pancreatic cancer.

Keywords: Pancreatic cancer, Pain management

Figures and Tables

Fig. 1

Pain scores and documentation of pain.

Fig. 2

Treatment algorithm for pain management in pancreatic cancer. AAP, acetaminophen; NSAIDs, nonsteroidal anti-inflammatory drugs; TCAs, tricyclic antidepressants; NMDA, N-methyl-d-aspartate.

Fig. 3

Analgesic ladder was designed by the World Health Organization.37 AAP, acetaminophen; NSAIDs, nonsteroidal anti-inflammatory drugs.

Notes

^{Financial support} None.

^{Conflict of interest} None.

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ORCID iDs: Jong Jin Hyun
https://orcid.org/0000-0002-5632-7091
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