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Abstract
Case summary
A 33-year-old woman with a history of cleaning her contact lenses with tap water presented with decreased visual acuity for 1 day in the left eye. The patient showed diffuse corneal edema, stromal infiltration, and radial keratoneuritis, which were thought to be pathognomonic for Aeromonas keratitis. Based on the patient's clinical findings and past history, a diagnosis of Aeromonas keratitis was made and she was prescribed topical fortified cefazolin (50 mg/mL, 5%), tobramycin (3 mg/mL), and 0.02% chlorhexidine per hour. Culture results from the contact lens and contact lens solution confirmed infection by Aeromonas hydrophilia. Polymerase chain reaction results for Aeromonas were negative. After 8 days of treatment, the uncorrected visual acuity was 0.7/0.3 with improvement in her corneal findings.
Figures and Tables
Figure 1
Anterior segment photographs of the left eye at presentation. Small dense stromal infiltrates at the center (A, arrows) and radial keratoneuritis (B, arrow) were revealed at inferonasal area.
Figure 2
UPGMA phylogenetic trees based on the rpoB sequence. The relationships with the strains of genus Aeromonas and other closely related bacterial strains were shown. Nucleotide sequence of clinical isolate from the patient was revealed as Aeromonas hydrophilia in this tree (highlighted with box). Aeromonas species and Pseudomonas species were closely related in the tree. UPGMA = Unweighted Pair Group Method with Arithmetic Mean.
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