A Case Report of Juvenile Hypertrophy of the Breast in a 15-Year-Old Girl: Presented with Asymmetric Breast Enlargement and a Focal Mass-like Lesion

Jae Yeon Park; Sung Hun Kim; Na Young Jung; Bong Joo Kang; Ah Won Lee; Min-Sun Jin

doi:10.13104/imri.2019.23.2.175

Journal List > Investig Magn Reson Imaging > v.23(2) > 1129568

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Park, Kim, Jung, Kang, Lee, and Jin: A Case Report of Juvenile Hypertrophy of the Breast in a 15-Year-Old Girl: Presented with Asymmetric Breast Enlargement and a Focal Mass-like Lesion

Case Report

iMRI 2019;23(2):175-178.

Published online: 10 January 2019

DOI: https://doi.org/10.13104/imri.2019.23.2.175

A Case Report of Juvenile Hypertrophy of the Breast in a 15-Year-Old Girl: Presented with Asymmetric Breast Enlargement and a Focal Mass-like Lesion

Jae Yeon Park¹, Sung Hun Kim¹, Na Young Jung¹, Bong Joo Kang¹, Ah Won Lee², Min-Sun Jin²

¹Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea

²Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence to: Na Young Jung, M.D., Ph.D. Department of Radiology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 327 Sosa-ro, Bucheon-si, Gyeonggi-do 14647, Korea. Tel. +82-32-340-7369 Fax. +82-32-340-2544 E-mail: healmind@catholic.ac.kr

Received 3 May 2019 Revised 11 May 2019 Accepted 13 May 2019

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Juvenile hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies in adolescents. Here, we report a case involving a 15-year-old girl, presented with asymmetric enlargement of the left breast. Pronounced parenchymal thickening was found on initial ultrasonography (US). MRI and second-look US revealed a focal mass-like lesion on the left mid-lateral breast, confirmed as juvenile hypertrophy of the breast on pathology.

Keywords: Breast, Ultrasonography, Magnetic Resonance Imaging, Hypertrophy, Gigantomastia

References

1. Wolfswinkel EM, Lemaine V, Weathers WM, Chike-Obi CJ, Xue AS, Heller L. Hyperplastic breast anomalies in the female adolescent breast. Semin Plast Surg. 2013; 27:49–55.

2. Govrin-Yehudain J, Kogan L, Cohen HI, Falik-Zaccai TC. Familial juvenile hypertrophy of the breast. J Adolesc Health. 2004; 35:151–155.

3. Gunes D, Mutafoglu-Uysal K, Canda T, Saydam S, Cemeroglu AP, Olgun N. Unilateral juvenile (virginal) hypertrophy of the breast. Turk J Pediatr. 2008; 50:278–281.

4. Baker SB, Burkey BA, Thornton P, LaRossa D. Juvenile gigantomastia: presentation of four cases and review of the literature. Ann Plast Surg. 2001; 46:517–525. discussion 525–516.

5. Schumacher O, Ashkar W, Dabernig J, Nenadic I, Ingianni G. Juvenile gigantomastia of extreme magnitude: a case report. Ann Plast Surg. 2009; 63:369–372.

6. Gentimi F, Loupatatzi A, Euthimoglou KP, et al. Juvenile gigantomastia in a 12-year-old girl: a case report. Aesthetic Plast Surg. 2011; 35:414–417.

7. Selland DL, Korbin CD, Lester SC, et al. Gynecomastoid hyperplasia: imaging findings in six patients. Radiology. 2000; 214:553–555.

Fig. 1.

15-year-old girl with juvenile hypertrophy of the left breast. (a) Posteroanterior chest radiograph shows enlargement of left breast shadow (arrows), compared with the right one. A chest radiograph from 7 years ago (not shown), shows no asymmetry or soft tissue masses on the left chest. (b) Initial ultrasonography (US) images shows pronounced parenchymal thickening of the left breast, compared to the right breast (not shown). (c) Axial T2-weighted magnetic resonance (MR) image shows the enlarged left breast exhibiting diffuse high signal intensity, compared to right breast as well as a small oval mass (arrows) at the mid-lateral portion of the left breast, showing slightly higher signal intensity than the opposite normal breast parenchyma. (d) Axial T1-weighted MR image shows the enlarged left breast and a mass at the mid-lateral portion of the left breast (arrows), showing isointensity compared to the right breast parenchyma. (e) On axial contrast-enhanced T1-weighted MR image, the enlarged left breast exhibits slightly prominent background parenchymal enhancement, as well as a mass at the mid-lateral portion of the left breast (arrows), showing mild homogeneous enhancement. (f) Time intensity curves of dynamic contrast enhancement, with placement of regions of interest on the enhancing mass, are initial medium and delayed persistent patterns. (g) Second-look US after MR image revealed an approximately 2.2 cm circumscribed oval hypoechoic lesion at the mid-lateral portion of the left breast. (h) Low-power view (Hematoxylin & Eosin stain, × 40) of breast tissue from the mass on the left breast shows small duct proliferation, with periductal stromal fibrosis and focal inconspicuous lobules. (i) On high-power view (Hematoxylin & Eosin stain, × 200), involved ducts exhibit epithelial hyperplasia with formation of small, abortive, short, and tapering micropapillae.

TOOLS

Similar articles