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초록
Purpose
The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea.
Methods
A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent t-tests, one-way ANOVA, Pearson's correlation coefficients, and multiple regression with SPSS/WIN 23.0.
Results
The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients’ QOL and accounted for 70% of the total variance.
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Table 1.
Demographic and Clinical Variables of Study Participants (N =112)
Table 2.
Prevalence of Menopausal Symptoms (N =112)
Table 3.
Correlation between Menopausal Symptoms and Quality of Life (N =112)
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