Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs Among Nurses in General Hospitals

Jiyoon Jung; Jeong Yun Park

doi:10.5388/aon.2019.19.2.106

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Jung and Park: Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs Among Nurses in General Hospitals

Original Article

Asian Oncol Nurs 2019;19(2):106-113.

Published online: 5 June 2019

DOI: https://doi.org/10.5388/aon.2019.19.2.106

Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs Among Nurses in General Hospitals

Jiyoon Jung¹, Jeong Yun Park²

¹Department of Nursing, Asan Medical Center, Seoul, Korea

²Department of Clinical Nursing, University of Ulsan, Seoul, Korea

^∗ This article is an addition based on the first author's master's thesis from University of Ulsan.

Address reprint requests to: Park, Jeong Yun Department of Clinical Nursing, University of Ulsan, 88 Olympic-ro, 43-gil, Songpa-gu, Seoul 05505, Korea Tel: +82-2-3010-5333 Fax: +82-2-3010-5332 E-mail: pjyun@ulsan.ac.kr

Received 1 Jun 201917 Jun 2019 Accepted 17 Jun 2019

This is an Open Access article distributed under the terms of the Creative Commons Attribution NoDerivs License (http://creativecommons.org/licenses/by-nd/4.0/) If the original work is properly cited and retained without any modification or reproduction, it can be used and re-distributed in any format and medium.

초록

Purpose

The purpose of this study was to investigate the level of compliance with the safety guidelines of anticancer drugs and identify the factors influencing compliance among general characteristics, knowledge of safety guidelines, self-efficacy, and workplace safety climate.

Methods

This study used a cross-sectional descriptive design and 143 nurses who care for patients with cancer were surveyed. Data were collected from March 19 to March 31, 2018.

Results

The subjects’ average age was 29.2±5.1 years, and oncology nursing experience was 5.07±4.01 years. Workplace safety climate, age, work site, and oncology nursing experience had a significant influence on nurses’ compliance with the safety guidelines of anticancer drugs. The explained variance for compliance was 23.5%.

Conclusion

The findings of this study indicate that the safety guidelines of anticancer drugs among nurses are expected to be better implemented by creating a safety-conscious environment. To maximize compliance nurses need to perform their tasks in an efficient manner, have institution-level active support, ready availability of personal protective equipment, appropriate education and a well-balanced workload.

Keywords: Antineoplastic agents, Safety, Guidelines, Compliance, Workplace

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Table 1.

General Characteristics of the Subjects (N =143)

Characteristics	Categories	n (%) or M ± SD
Age (years)	＜30	87 (60.8)
	30~39	50 (35.0)
	≥40	6 (4.2)
		29.2 ± 5.1
Gender	Male	0 (0.0)
	Female	143 (100.0)
Marital status	Single	97 (67.8)
	Married	46 (32.2)
Education	Diploma	3 (2.1)
	Bachelor	114 (79.7)
	≥ Master	26 (18.2)
Work site	Oncology ward	77 (53.8)
	Hematology ward	38 (26.6)
	Infusion room	14 (9.8)
	∗Others	14 (9.8)
Oncology nursing experi-	＜1	24 (16.8)
ence (year)	1~5	59 (41.2)
	6~10	40 (28.0)
	≥11	20 (14.0)
		5.07 ± 4.01
Chemotherapy	≤3	42 (29.4)
workload	4~6	71 (49.1)
(number of patients)	≥7	30 (21.0)
		6.7 ± 7.4
Chemotherapy	Yes	90 (62.9)
exposure experience	No	53 (37.1)

^∗ VIP ward, clinical research ward.

Table 2.

Scores of Compliance with Guidelines, Knowledge, Self-efficacy, Workplace Safety Climate (N =143) Total score

Variables	Categories	Total score
Variables	Categories	M ± SD
Compliance with guidelines	Pre-administration	4.40 ± 0.404.40 0.52
	Pre-administration	4.40 ± 0.52
	Administration Discard	4.55 ± 0.544.26 ± 0.57
PPE use		3.68 ± 0.55
	Glove	4.70 ± 0.45
	Mask	4.62 ± 0.67
	Gown	1.71 ± 1.12
Knowledge of safety guidelines		7.19 ± 0.93
Self-efficacy		3.77 ± 0.39
Workplace safety climate		3.78 ± 0.59

PPE= personal protective equipment.

Table 3.

Compliance with Safety Guidelines of Anticancer drug according to General Characteristics (N =143)

Characteristics	Categories	Compliance
Characteristics	Categories	M ± SD	t or F	p	Scheffé
Age (years)	＜30 ^a	4.47 ± 0.41	4.64	.011	a＜ b
	30~39 ^b	4.66 ± 0.22
	≥40 ^c	4.56 ± 0.42
Marital state	Single	4.50 ± 0.38	-1.66	.099
	Married	4.61 ± 0.32
Education	Diploma	4.49 ± 0.15	1.69	.187
	Bachelor	4.51 ± 0.38
	Master	4.66 ± 0.29
Work site	Oncology ward ^a	4.41 ± 0.39	8.85	＜.001	a＜ b
	Hematology ward ^b	4.75 ± 0.24
	Infusion room ^c	4.56 ± 0.31
	Others ^d	4.61 ± 0.26
Oncology nursing experience (year)	＜1	4.35 ± 0.44	2.77	.044
	1~5	4.55 ± 0.38
	6~10	4.60 ± 0.30
	≥ 11	4.61 ± 0.29
Chemotherapy workload (number of patients)	≤ 3	4.57 ± 0.43	0.31	.732
	4~6	4.51 ± 0.37
	≥ 7	4.55 ± 0.27
Chemotherapy exposure experience	Yes	4.50 ± 0.39	3.13	.084
	No	4.61 ± 0.31

Table 4.

Relationship among Compliance with Guidelines and Predictor Variables (N =143)

Variables	Compliance with guidelines	Knowledge of guidelines	Self-efficacy	Workplace safety climate
Variables	r (p)	r (p)	r (p)	r (p)
Compliance with guidelines	1
Knowledge of safety guidelines	.12 (.145)	1
Self-efficacy	.10 (.223)	.10 (.244)	1
Workplace safety climate	.26 (.002)	.03 (.709)	.20 (.020)	1

Table 5.

Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs (N =143)

Variables		B	SE	b	t	p	VIF
(Constant)		80.77	9.09		9.05	＜.001
Knowledge of the safety gui	idelines	1.48	0.77	.15	1.92	.057	1.07
Self-efficacy		0.09	0.11	.06	0.80	.425	1.13
Workplace safety climate		0.21	0.07	.23	2.92	.004	1.14
Work site	Oncology ward	ref
	Hematology ward	8.54	1.67	.40	5.03	＜.001	1.17
	Infusion room	3.13	2.59	.10	1.21	.229	1.23
	Others∗	4.31	2.47	.14	1.74	.084	1.19
Oncology nursing	＜1	ref
experience	1~5	4.01	2.05	.21	1.95	.053	2.12
	6~10	5.48	2.18	.26	2.51	.013	2.00
	≥11	5.15	2.67	.19	1.93	.056	1.77
			Adj. R²= .235, F= 5.85, p＜.001

^∗ VIP ward, clinical research ward.

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