Abstract
Figures and Tables
Fig. 1
Clinical and radiological feature. A. Intraoral photograph. Despite the presence of right mandibular swelling, there was no specific finding in the intraoral findings. B. Panoramic view. It was difficult to locate specific findings on panoramic examination. C, D. Osteolytic findings were observed on computed tomography (CT), including a well-defined, buccolingual expansile lesion (C: axial view, D: coronal view). Profuse periosteal reaction was also observed around the lesion.
![jkaoms-45-167-g001](/upload/SynapseData/ArticleImage/3070jkaoms/jkaoms-45-167-g001.jpg)
Fig. 2
Histologic feature. Langerhans cells and eosinophils are densely infiltrated. It was proved to be Langerhans cell histiocytosis (CD1a/S-100 positive) on additional immunohistological staining (H&E staining, ×200).
![jkaoms-45-167-g002](/upload/SynapseData/ArticleImage/3070jkaoms/jkaoms-45-167-g002.jpg)
Fig. 3
Bone scan images. A. Before therapy. A focal uptake was observed in the right mandible. B. After therapy. No abnormal uptake was observed.
![jkaoms-45-167-g003](/upload/SynapseData/ArticleImage/3070jkaoms/jkaoms-45-167-g003.jpg)
Fig. 4
Clinical and radiological feature. A. Intraoral photograph. Clinical examination revealed swelling of the right mandible, pain in the affected area, mobility of #85, and gingival swelling and bleeding. B. Panoramic view. It was difficult to locate specific findings on panoramic examination. C, D. Osteolytic findings were observed on computed tomography (CT), including a well-defined, buccolingual expansile lesion (C: axial view, D: coronal view). Profuse periosteal reaction was also observed around the lesion.
![jkaoms-45-167-g004](/upload/SynapseData/ArticleImage/3070jkaoms/jkaoms-45-167-g004.jpg)
Acknowledgements
Notes
Authors' Contributions D.S.H. and J.S.L. participated in data collection and wrote the manuscript. U.K.K., H.R.P., M.H.R., J.H.L., Y.H.J., and G.C.K. participated in the study design and performed the radiologic and histologic analysis. All authors read and approved the final manuscript.
How to cite this article Hwang DS, Lee JS, Kim UK, Park HR, Ryu MH, Lee JH, et al. Langerhans cell histiocytosis of the mandible: two case reports and literature review. J Korean Assoc Oral Maxillofac Surg 2019;45:167–72. https://doi.org/10.5125/jkaoms.2019.45.3.167
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