Journal List > Korean J Pediatr Infect Dis > v.3(2) > 1126600

TOOLS
Kim, Yang, Sohn, and Kim: A Case of Epstein Barr Virus-Associated Hemophagocytic Syndrome Confirmed by mRNA In Situ Hybridization and Polymerase Chain Reaction
Case Report

Korean Journal of Pediatric Infectious Diseases 1996; 3(2): 200-206.

Published online: 30 November 1996

DOI: https://doi.org/10.14776/kjpid.1996.3.2.200

A Case of Epstein Barr Virus-Associated Hemophagocytic Syndrome Confirmed by mRNA In Situ Hybridization and Polymerase Chain Reaction

Chung Han Kim, M.D., Chang Hyun Yang, M.D., Young Mo Sohn, M.D., Hoguen Kim, M.D.*

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.

*Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Copyright © 1996 The Korean Society of Pediatric Infectious Diseases

Abstract

Virus associated hemophagocytic syndrome(VAHS), a class II histiocytosis syndrome, is characterized by high fever, liver dysfunction, coagulation abnormalities, and generalized histiocytic proliferation with marked hemophagocytosis in bone marrow and lymph nodes.
VAHS is associated with several viral infections including Epstein Barr virus which has a relatively high mortality rate.
We report a fatal case of Epstein Barr virus associated hemophagocytic syndrome and its diagnosis by mRNA in situ hybridization and polymerase chain reaction.
A brief review of related literaure is also presented.

Keywords: Epstein Barr virus, Virus-associated hemophagocytic syndrome

TOOLS
Similar articles