Diffuse mesotheliomas of the pleura and peritoneum are considered "signal tumors" of asbestos exposure. Although asbestos use in Korea started before the national liberation, it rose abruptly with economic development in 1970's. Considering latent period of mesotheliomas as twenty years, occupational mesothelioma cases would increase rapidly. In Korea construction is a major industry which use asbestos. Because workers in construction industry are mostly composed of daily based workers, it is hard to calculate the number of workers involving asbestos related work, to manage them with organized method, to educate them about adverse effects of asbestos and protection methods, to check health status of them periodically, and to follow them up. Although a case of occupational mesothelioma which was found in a asbestos textile worker have been reported, no case related with construction workers have been reported so far in Korea. The authors experienced occupational malignant pleural mesothelioma combined with asbestosis in a boilermaker and plumber in a construction industry.