Ethyl cyanoacrylate is used as a component of adhesives used in the industrial, domestic, and medical fields. It is known to cause mucosal irritation, contact dermatitis and respiratory discomfort. However, reports of combined occupational asthma and rhinitis are rare, especially in Korea. We report a case of occupational asthma and rhinitis suspected to be caused by exposure to ethyl cyanoacrylate.

A 36-year-old woman presented with rhinorrhea, cough, dyspnea and chest discomfort after exposure to ethyl cyanoacrylate adhesive at an assembly area of a plastic products manufacturing company. Nasal endoscopy revealed watery rhinorrhea and hypertrophy of nasal turbinates, which were compatible with rhinitis. The methacholine provocation test showed a positive result. Daily variability of peak expiratory flow increased on work days, but decreased during non-work days. Based on these findings, we diagnosed this case as a combination of occupational asthma and rhinitis suspected to be caused by exposure to ethyl cyanoacrylate.

There needs to be increased awareness regarding occupational asthma and rhinitis caused by exposure to ethyl cyanoacrylate.