Journal List > J Korean Soc Spine Surg > v.25(Suppl 1) > 1125269

Shin, Nam, Kim, Kim, Kim, Ahn, and Kim: Overview of the Management of Chronic Non-Cancer Pain in Patients with Spinal Disease

Abstract

Study Design

Cross-sectional, multicenter survey study.

Objectives

The objective of this study was to investigate the pain status, pain management methods, and pain experience after treatment among patients suffering from chronic non-cancer pain due to spinal disease.

Summary of the Literature Review

No thorough investigation of the current status of chronic non-cancer pain management in patients with spinal disease has recently been reported.

Materials and Methods

We surveyed 330 patients with chronic non-cancer pain who visited spine clinics in Korea.

Results

Prior to treatment, 86.7% of the patients had severe pain and 99.4% of the patients had taken oral analgesics for pain control. After treatment, the percent of patients with severe pain was reduced to 42.1%, and 52.4% of patients responded that they experienced intermittent pain. End of dose failure was experienced by 29.1% of patients, and 41.7% of patients experienced pain again 3–6 hours after taking analgesics. Furthermore, 8.2% of patients experienced breakthrough pain, and 29.1% of patients experienced pain that interfered with sleeping.

Conclusions

Many patients with chronic pain reported experiencing pain due to end of dose failure after medication. As the causes of chronic pain are complex, appropriate analgesics should be considered and selected for effective pain management.

REFERENCES

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Fig. 1.
The interval of time for intermittent pain.
jkss-25-91f1.tif
Table 1.
Demographic and disease characteristics
Characteristic Number of patients (%)
Demographic characteristics  
Sex  
  Male 133(40.3)
  Female 197(59.7)
Age (yr)  
  20-29 8(2.4)
  30-39 11(3.3)
  40-49 11(3.3)
  50-59 42(12.7)
  60-69 106(32.4)
  ≥70 152(46.1)
Disease characteristics  
  Diagnosis  
  Headache 5(1.5)
  Trigeminal neuralgia 0(0.0)
  Facial neuralgia 0(0.0)
  Omalgia 22(6.7)
  Cervical disc disorder 21(6.4)
  Lumbar disc disorder 219(66.4)
  Failed back surgery syndrome 58(17.6)
  Degenerative knee osteoarthritis 36(10.9)
  Rheumatoid arthritis 17(5.2)
  Foot and ankle pain 7(2.1)
  Diabetic neuralgia 2(0.6)
  Others: melosalgia etc. 27(8.2)

Diagnosis: Patients were able to select more than 1 response.

Table 2.
Pain severity and type at the first visit
  Number of patients (%)
Pain severity at the first visit  
  Mean±SD 9.02±1.41 (NRS score)
  Mild 3(0.9)
  Moderate 41(12.4)
  Severe 286(86.7)
Pain type at the first visit  
  Continuous pain 204(61.8)
  Regularly intermittent pain 18(5.5)
  Irregularly intermittent pain 108(32.7)

NRS, numerical rating score.

Table 3.
Pain management at the first visit
  Number of patients (%)
Pain management  
Treatment type  
  Oral analgesics 328(99.4)
  Transdermal analgesic patch 44(13.3)
  Analgesic injections 49(14.8)
  Antidepressants 3(0.9)
  Gastrointestinal agents (pill, gel type et al.) 103(31.2)
  Other interventions 20(6.1)
Frequency of oral analgesics  
  Once daily 72(22.0)
  Twice daily 183(55.8)
  Three times daily 73(22.3)
Percentage of pain reduction during the last month  
  0% 1(0.3)
  10% 3(0.9)
  20% 15(4.5)
  30% 28(8.5)
  40% 12(3.6)
  50% 53(16.1)
  60% 32(9.7)
  70% 84(25.5)
  80% 70(21.2)
  90% 26(7.9)
  100% 6(1.8)

Treatment type: Patients were able to select more than 1 response.

Frequency of oral analgesics; based on replies from 328 patients who reported taking oral analgesics.

Table 4.
Recent pain severity and type
  Number of patients (%)
Recent pain severity  
The most intense pain severity during the last week
  Mild 93(28.2)
  Moderate 98(29.7)
  Severe 139(42.1)
The least intense pain severity during the last week
  Mild 266(80.6)
  Moderate 56(17.0)
  Severe 8(2.4)
Pain severity on visit date  
  Mild 205(62.1)
  Moderate 97(29.4)
  Severe 28(8.5)
Pain type  
Pain type on visit date  
  Continuous pain 54(16.4)
  Regularly intermittent pain 6(1.8)
  Irregularly intermittent pain 173(52.4)
  Slight pain 97(29.4)
Table 5.
The incidence of end-of-dose failure, breakthrough pain, an pain in sleep
Pain incidence Number of patients (%)
Incidence of end-of-dose failure  
  Yes 96(29.1)
  No 234(70.9)
The time interval before experiencing pain after medication
  Within 1 hour 22(22.9)
  After 1–2 hours 11(11.5)
  After 3–6 hours 40(41.7)
  After 7–9 hours 16(16.7)
  After 9–12 hours 4(4.2)
  Above 12 hours 3(3.1)
Incidence of breakthrough pain  
  Yes 27(8.2)
  No 303(91.8)
Frequency of breakthrough pain in last month  
  1-2 times/month 11(40.7)
  3-4 times/month 6(22.2)
  5-10 times/month 7(25.9)
  Above 10 times/month 3(11.1)
Incidence of pain in sleep  
  No pain 234(70.9)
  ≤1/ week 47(14.2)
  1-2/ week 24(7.3)
  ≥3/ week 25(7.6)
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