Journal List > Korean J Gynecol Oncol Colposc > v.12(3) > 1123717

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Hong, Moon, Oh, Kim, Seong, Hong, and Lee: Elevated Serum Alpha-Fetoprotein Associated with Sertoli-Leydig Cell Tumor of Ovary
Case Report

Korean Journal of Gynecologic Oncology and Colposcopy 2001; 12(3): 254-258.

Published online: 13 March 2019

DOI: https://doi.org/10.3802/kjgoc.2001.12.3.254

Elevated Serum Alpha-Fetoprotein Associated with Sertoli-Leydig Cell Tumor of Ovary

Jun Sik Hong, Myoung Jin Moon, Dong Chul Oh, Yon Ju Kim, Seok Ju Seong, Sung Ran Hong, Ki Heon Lee

Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.

Department of Pathology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.

Copyright © Korean Society of Gynecologic Oncology and Colposcopy

Abstract

A case of intermediate differentiated Sertoli-Leydig cell tumor with elevated Alpha-fetoprotein (AFP) levels occurred in a 15-year-old girl. No germ cell component and no heterologous elements were identified. Secretion of AFP by Sertoli-Leydig cell tumor has rarely been mentioned previously, and its mechanism is difficult to explain. We present this case with review of related literatures.

Keywords: Alpha-fetoprotein, Sertoli-Leydig cell tumor, AFP

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