Journal List > Korean J Gynecol Oncol > v.18(4) > 1123432

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Kim, Park, Lee, Koo, and Park: Expression of c-Met in ovarian epithelial tumor
Original Article

Korean Journal of Gynecologic Oncology 2007; 18(4): 284-288.

Published online: 12 March 2019

DOI: https://doi.org/10.3802/kjgo.2007.18.4.284

Expression of c-Met in ovarian epithelial tumor

Bo Seop Kim, Il Soo Park, Yoon Soon Lee, Tae Bon Koo, Tae In Park

Depatment of Obsterics and Gynocology, Kyungpook National University College of Medicine, Daegu, Korea.

Depatment of Pathology, Kyungpook National University College of Medicine, Daegu, Korea.

parkis@knu.ac.kr

Copyright © Korean Society of Gynecologic Oncology and Colposcopy

Abstract

OBJECTIVE

This study was performed to evaluate the expression of c-Met in epithelial ovarian carcinoma.

METHODS

Paraffin-embedded tissues from 50 epithelial ovarian adenocarcinomas were stained immunohistochemically for c-Met expression. The expression of c-Met was correlated with clinicopathologic parameters including, histologic type, tumor size, and tumor stage.

RESULTS

c-Met expression was found in 29 cases (58%) among 50 ovarian cancers. In clinicopathologic study, c-Met expression of epithelial ovarian carcinomas did not show the correlation with clinicopathologic parameters such as histologic type, tumor size and stage.

CONCLUSION

c-Met expression might be a potential prognostic marker for patients with advanced stage epithelial ovarian cancers. However, larger population-based studies should be performed to determine the prognostic potential of c-Met expression in advanced ovarian carcinoma.

Keywords: c-Met, Epithelial ovarian cancer, Prognosis

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