Following is a case report of giant cell tumor of the metacarpal bone of rlght thumb treated with surgical method. The metacarpal bone except both articular surfaces was excised and replaced with an autogenous iliac bone graft. The graft bone was fixed with 3 Kirschner's wires and the thumb was immobilized with plaster cast. There has been no evidence fo recurrence during the 6 years following and function of the hand is normal.