Journal List > J Korean Ophthalmol Soc > v.60(5) > 1122591

Yoon and Kwon: Features of Pinguecula Analyzed by Anteroir Segment Optical Coherence Tomography

Abstract

Purpose

To analyze the correlation between clinical features and degree of scleral invasion using anterior segment optical coherence tomography.

Methods

The size, elevation, color, and degree of vascularization were examined in 50 patients (17 males and 33 females) who visited our clinic between February 2017 and April 2018. The thickness and scleral involvement were analyzed by anterior segment optical coherence tomography.

Results

The average horizontal diameter of the pinguecula was 2.37 ± 1.12 mm, which showed significant positive correlations with the thickness and dimension (correlation coefficients: 0.34 and 0.42, respectively). The vertical diameter was 2.21 ± 0.91 mm, which showed significant correlations with thickness, scleral involvement, and dimension (correlation coefficients: 0.22, 0.61, and 0.33, respectively). The correlation coefficient with scleral invasion thickness was as high as 0.61. The average diameter was 2.29 ± 0.97 mm, which was also significantly correlated with thickness and dimension (correlation coefficients: 0.40 and 0.54, respectively). Overall thickness was significantly greater in the elevation group (average 0.66 ± 0.35 mm) than the flat group (0.57 ± 0.23 mm). Thickness was significantly greater in the severe vascularization group (0.70 ± 0.19 mm) than in the less severe vascularization group (0.50 ± 0.13 mm) (p = 0.01).

Conclusions

Anterior segment OCT findings revealed that the larger and more vascularized pinguecula were significantly thicker and had more scleral involvement.

Figures and Tables

Figure 1

Anterior segment photographs of pinguecula by color. (A) White, (B) yellow, (C) brown.

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Figure 2

Anterior segment photographs of pinguecula by elevation. (A) Flat, (B) mild elevation, (C) noticeable elevation.

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Figure 3

Anterior segment photographs of pinguecula by vascularization. (A) Mild, (B) moderate, (C) severe.

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Figure 4

Anterior segment photography of pinguecula and optical coherence tomography of pinguecula section (yellow line) according to progression. Anterior segment photography and anterior segment optical coherence tomography shows mild (A, B) and moderate (C, D) pinguecula with distinct scleral line (red arrow) without scleral invasion. In severe pinguecula, anterior segment photographs show marked vascularization and elevation (E), anterior segment optical coherence tomography shows thicker and more scleral invasion with distinct scleral line (red arrow) (F).

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Figure 5

Anterior segment photography and optical coherence tomography of pinguecula with scleral invasion. Anterior segment photograph shows vascularization and elevation of pinguecula (A). Anterior segment optical coherence tomography shows thick (double head red arrow) conjunctival stroma and scleral invasion (double head blue arrow) with large dimension (close yellow line) (B). Scleral invasion refers the distance between normal scleral line (green dotted line) and scleral involvement (double head blue arrow).

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Table 1

Baseline characteristics of the study population to compare the OCT findings and clinical findings of pinguecula

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Values are presented as mean ± standard deviation or number (%).

OCT = optical coherence tomography; AS-OCT = anterior segment optical coherence tomography.

Table 2

Correlation analysis between clinical features and anterior segment optical coherence tomographys of pinguecula

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*Pearson's correlation coefficient; p < 0.05 was regarded as statistically significant.

Table 3

Anterior segment optical coherence tomography parameters according to color of pinguecula

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Values are presented as mean ± standard deviation unless otherwise indicated.

AS-OCT = anterior segment optical coherence tomography.

*Kruskal-Wallis test.

Table 4

Anterior segment optical coherence tomography parameters according to elevation of pinguecula

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Values are presented as mean ± standard deviation unless otherwise indicated.

AS-OCT = anterior segment optical coherence tomography.

*Kruskal-Wallis test.

Table 5

Post hoc analysis of difference of total thickness according to elevation of pinguecula

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Values are presented as mean ± standard deviation unless otherwise indicated.

*Bonferroni's method.

Table 6

Post hoc analysis of difference of scleral involved thickness according to elevation of pinguecula

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Values are presented as mean ± standard deviation unless otherwise indicated.

*Bonferroni's method.

Table 7

Anterior segment optical coherence tomography parameters according to vascularization of pinguecula

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Values are presented as mean ± standard deviation unless otherwise indicated.

AS-OCT = anterior segment optical coherence tomography.

*Kruskal-Wallis test.

Table 8

Post hoc analysis of difference of total thickness according to vascularization of pinguecula

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Values are presented as mean ± standard deviation unless otherwise indicated.

*Bonferroni's method.

Notes

Conflicts of Interest The authors have no conflicts to disclose.

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