Journal List > Korean J Schizophr Res > v.17(2) > 1122197

Korean J Schizophr Res. 2014 Oct;17(2):63-71. Korean.
Published online Oct 27, 2014.  https://doi.org/10.16946/kjsr.2014.17.2.63
Copyright © 2014 Korean Society for Schizophrenia Research
Emotional Dysregulation, Attributional Bias, Neurocognitive Impairment in Individuals at Ultra-High Risk for Psychosis and with Schizophrenia : Its Association with Paranoia
Nam Wook Kim, MD,1,2 Yun Young Song, MD,1,3 Jin Young Park, MD, PhD,1,2 Seo Yeon Baek, BA,1 Jee In Kang, MD, PhD,1,2 Eun Lee, MD, PhD,1,2 and Suk Kyoon An, MD, PhD1,2
1Section of Affect and Neuroscience, Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
2Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea.
3Department of Psychiatry, Seoul National Hospital, Seoul, Korea.

Address for correspondence: Suk Kyoon An, Department of Psychiatry, Yonsei University College of Medicine, 119 Gyeonchung-daero 1926beon-gii, Gwangju 464-110, Korea. Tel: 031-760-9404, Fax: 031-761-7582, Email: ansk@yuhs.ac
Received Jun 28, 2014; Revised Aug 19, 2014; Accepted Aug 25, 2014.

Abstract

Objectives

Paranoia is a complex phenomenon, affected by a number of factors such as depression, trait anxiety, and attributional bias in schizophrenia. The aim of this study was to explore whether paranoia within continuum of clinical and subclinical states is associated with emotional dysregulation, attributional bias and neurocognitive impairment in whole individuals of normal controls, ultra-high risk (UHR) for psychosis and schizophrenia.

Methods

101 normal controls, 50 participants at UHR for psychosis, and 49 schizophrenia patients were recruited. All subjects were asked to complete self-reported paranoia scale and emotional dysregulation scales including Rosenberg's self-esteem, Spielberg's state-trait anxiety inventory and Beck depression inventory. The attributional style was assessed by Ambiguous Intentions Hostility Questionnaire (AIHQ). Participants were also requested to complete the comprehensive neurocognitive battery.

Results

Multiple linear regression analysis showed that paranoia were found to be associated with emotional dysregulation (state anxiety, trait anxiety and depression), composite blaming bias in ambiguous situation, impairment of attention and working memory in whole participants [F (9, 190)=34.85, p<0.001, adjusted R2=0.61].

Conclusion

The main findings suggest that paranoia is a complex affective and cognitive structure that may be associated with emotional dysregulation, blaming bias and attention and working memory impairment in clinical and non-clinical paranoia.

Keywords: Paranoia; Schizophrenia; Ultra-high risk for psychosis; Neurocognition; Emotional dysregulation; Attributional bias

Tables


Table 1
Demographic and clinical characteristics of participants
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Table 2
Intercorrelation between paranoia scale and other variables
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Table 3
Multiple linear regression analysis of paranoia score with other variables
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