Eosinophilic Granulomatosis with Polyangiitis Diagnosed by Gallbladder Tissue

WooSeong Jeong; Changlim Hyun; Jinsoek Kim

doi:10.4078/jrd.2019.26.1.83

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Jeong, Hyun, and Kim: Eosinophilic Granulomatosis with Polyangiitis Diagnosed by Gallbladder Tissue

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J Rheum Dis 2019;26(1):83-84.

Published online: 31 January 2019

DOI: https://doi.org/10.4078/jrd.2019.26.1.83

Eosinophilic Granulomatosis with Polyangiitis Diagnosed by Gallbladder Tissue

WooSeong Jeong¹, Changlim Hyun², Jinsoek Kim¹

¹Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea

²Department of Pathology, Jeju National University School of Medicine, Jeju, Korea

Corresponding to: Jinseok Kim http://orcid.org/0000-0001-7518-3284 Division of Rheumatology, Department of Internal Medicine, Jeju National University School of Medicine, 15 Aran 13-gil, Jeju 63241, Korea. E-mail: slera@yahoo.com

Received 16 August 201828 August 2018 Accepted 11 September 2018

This is a Open Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.

REFERENCES

1. Ebert EC. Gastrointestinal manifestations of churg-strauss syndrome. J Gastroint Dig Syst. 2011; 1:1–3.

2. Ye L, Lu X, Xue J. Eosinophilic granulomatosis with polyangiitis complicated by cholecystitis: a case report and review of the literature. Clin Rheumatol. 2016; 35:259–63.

Figure 1.

Abdominal and pelvic computed tomography scan showing diffuse wall thickening of the gallbladder with some irregularity.

Figure 2.

Granuloma surrounds the blood vessel (blue arrows) and granulomatous inflammation is also noted in and around the blood vessels (H&E, ×40).

Figure 3.

The vessel wall (yellow arrows) is destructed by inflammatory infiltrates in the right upper area of the vessel (vasculitis with fibrinoid necrosis, red arrow). Many eosinophils which have bright red colored cytoplasm infiltrates into and around the vessel (black arrows) (H&E, ×200).

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