Journal List > Dement Neurocogn Disord > v.12(2) > 1120815

Dement Neurocogn Disord. 2013 Jun;12(2):33-40. Korean.
Published online Jun 30, 2013.  https://doi.org/10.12779/dnd.2013.12.2.33
© 2013 Korean Dementia Association
Features of Semantic Language Impairment in Patients with Amnestic Mild Cognitive Impairment
Hyunjoo Choi, Ph.D.,* Jee Hyun Kim, M.D., Chang Min Lee, M.D., and Jae Il Kim, M.D.
*Department of Communication Disorders, Korea Nazarene University, Cheonan, Korea.
Department of Neurology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.

Address for correspondence: Hyunjoo Choi, Ph.D. Department of Communication Disorders, Korea Nazarene University, 48 Wolbong-ro, Seobuk-gu, Cheonan 330-718, Korea. Tel: +82-41-570-1677, Fax: +82-41-570-7846, Email: hjchoi@kornu.ac.kr
Received Jan 30, 2013; Revised Jun 15, 2013; Accepted Jun 15, 2013.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

Background

To elucidate the earliest changes of language function in patients with dementia of Alzheimer's type (DAT), performance on the various semantic language tasks were compared between patients with amnestic mild cognitive impairment (aMCI) (n=20), mild DAT (n=20) and normal cognition elderly individuals (NC, n=20).

Methods

Language tasks included levels of word, sentence and discourse. In the word level, confrontation naming test (Korean version-Boston Naming Test, K-BNT) and the verbal fluency (semantic and phonemic fluency) tasks were used. In the sentence level, the verbal definition tasks including 24 nouns four categories were used. In the discourse level, the Boston Cookie-Theft picture description task was used. The picture description task was analyzed for both productive aspect (total number of sentences, total number of phrases and phrases per sentence) and semantic aspect (ratio of CIU: Correct Information Unit).

Results

The results from this study are as follow: 1) In the confrontation naming test, mild DAT group showing worse performances than the NC and aMCI group. However, no differences were observed between the NC and aMCI group. 2) The performances of verbal fluency task showed significantly differences between the all groups. 3) In the verbal definition task, performances of NC group showing better performances than aMCI and mild DAT group. However, no differences were observed between the aMCI and mild DAT group. 4) In the picture description task, performances of the aMCI and mild DAT group were non-informative and inefficient in semantic aspect compared to the NC group. However, no differences were observed between the three groups on productive aspect.

Conclusions

These results demonstrated that the deficit of semantic language is readily identified in the aMCI stage, and it can be revealed by tasks of sentence and discourse level.

Keywords: Amnestic mild cognitive impairment; Dementia of Alzheimer's type; Confrontation naming; Verbal fluency; Verbal definition; Discourse

Tables


Table 1
The characteristics of the subjects
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Table 2
Results of the performances of K-BNT and verbal fluency task
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Table 3
Result of the performances of verbal definition task
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Table 4
Result of the performances of picture description task
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Notes

This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (NRF-2001-332-B00454).

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