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A Case of Insulinoma Presenting as Repetitive Abnormal Behavior with Amnesia
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Sang Wuk Sohn, M.D.,*
Byeol A Yoon, M.D.,*
Hyung Jin Lee, M.D.,*
Dong-Hyun Shim, M.D.,*
and Kyung Won Park, M.D. *,†
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*Department of Neurology, Dong-A University College of Medicine, Busan, Korea.
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†Cognitive Disorders and Dementia Center, Dong-A University Hospital, Busan, Korea.
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Address for correspondence: Kyung Won Park, M.D. Department of Neurology, Dong-A University College of Medicine, 32 Daesingongwon-ro, Seo-gu, Busan 602-715, Korea. Tel: +82-51-240-2966, Fax: +82-51-245-2966, Email: neuropark@dau.ac.kr
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Received Dec 01, 2014; Revised Dec 24, 2014; Accepted Dec 24, 2014.
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract
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Insulinomas are very rare tumors. Diagnosis of insulinoma is often delayed or misdiagnosed because of its various symptoms. We report a patient with hypoglycemic encephalopathy who had repetitive behavior changes, diagnosed as a pancreatic insulinoma. A 52 years old man was referred to a memory and dementia clinic for evaluation of his repetitive abnormal behavior changes. He has threatened his wife with violent acts and showed aggressive behaviors, but he couldn't remember when he was recovered to normal state. During the hospitalization, we noticed that his repetitive abnormal behaviors were correlated to severe hypoglycemia. After we corrected glucose level, his symptoms were disappeared. We performed an abdomen-pelvis CT scan, revealing pancreatic head tumor. After he took surgical treatment, His symptoms were fully recovered. Our case demonstrates that various neurological symptoms, such as abnormal behavior, rarely occur due to recurrent hypoglycemia in patient with insulinoma.
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