Journal List > Asian Oncol Nurs > v.19(1) > 1120003

Jeon and Kim: Perception and Satisfaction of Anticancer Drug Clinical Trials in Cancer Patients

Abstract

Purpose

The purpose of this study was to investigate the perception and satisfaction of cancer patients participating in clinical trials of anticancer drugs and the factors affecting their satisfaction.

Methods

The participants were cancer patients who participated in more than two cycles of clinical trials at a tertiary hospital in Seoul, Korea. Questionnaires were used to assess the perception and satisfaction of clinical trials of anticancer drugs.

Results

A total of 106 patients participated. The average perception and satisfaction regarding clinical trials among patients on a 5 point scale was 3.99±0.45 and 4.09±0.55 respectively. There was a significant difference in the correlation among participants' perception and their satisfaction (r =.67, p<.001). Regression analysis revealed that satisfaction was explained by, perception of clinical trials (β =.67, p<.001), participation period 30~59 days (β =.21, p=.009), and participation period over 60 days (β=.20, p=.013). These variables explained 48.7% of the variance of clinical trial satisfaction.

Conclusion

The results of this study suggest that changes in perceptions of clinical trials are needed to improve satisfaction of anticancer drug clinical trials. This can be used as a basis for improving the quality of clinical trials and education programs for cancer patients participating in clinical trials.

Figures and Tables

Table 1

Differences in Perception and Satisfaction of Participants according to General and Clinical Characteristics (N=106)

aon-19-18-i001

*Glottic cancer, thymic cancer, buccal cancer, peritoneal cancer; Acute myeloid leukemia M2, small cell lung cancer extensive disease.

Table 2

Differences in Perception and Satisfaction of Participants according to Clinical Trial related Characteristics (N=106)

aon-19-18-i002
Table 3

Levels of Perception and Satisfaction about Clinical Trials of Anticancer Drugs (N=106)

aon-19-18-i003
Table 4

Correlation among Participants'Perception and Satis-faction about Clinical Trials of Anticancer Drugs (N=106)

aon-19-18-i004
Table 5

Influencing Factors on Satisfaction about Clinical Trials of Anticancer Drugs (N=106)

aon-19-18-i005

VIF= Variance inflation factor; Participation period <30= 0.

Notes

The article is a revision of the first author's mater's thesis from University of Ulsan.

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ORCID iDs

Ju Kyung Jeon
https://orcid.org/0000-0002-9404-6012

Jeong Hye Kim
https://orcid.org/0000-0001-5384-706X

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