Perception and Satisfaction of Anticancer Drug Clinical Trials in Cancer Patients

Ju Kyung Jeon; Jeong Hye Kim

doi:10.5388/aon.2019.19.1.18

Journal List > Asian Oncol Nurs > v.19(1) > 1120003

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Jeon and Kim: Perception and Satisfaction of Anticancer Drug Clinical Trials in Cancer Patients

Original Article

Asian Oncology Nursing 2019; 19(1): 18-26.

Published online: 31 March 2019

DOI: https://doi.org/10.5388/aon.2019.19.1.18

Perception and Satisfaction of Anticancer Drug Clinical Trials in Cancer Patients

Ju Kyung Jeon¹

, Jeong Hye Kim²

¹Department of Nursing, Asan Medical Center, Seoul, Korea.

²Department of Clinical Nursing, University of Ullsan, Seoul, Korea.

Address reprint requests to: Jeon, Ju Kyung. Department of Clinical Nursing, University of Ullsan, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea. Tel: +82-2-3010-5335, Fax: +82-2-3010-5332, kimjh@amc.seoul.kr

Received 18 January 2019 Revised 20 February 2019 Accepted 5 March 2019

Korean Oncology Nursing Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nd/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study was to investigate the perception and satisfaction of cancer patients participating in clinical trials of anticancer drugs and the factors affecting their satisfaction.

Methods

The participants were cancer patients who participated in more than two cycles of clinical trials at a tertiary hospital in Seoul, Korea. Questionnaires were used to assess the perception and satisfaction of clinical trials of anticancer drugs.

Results

A total of 106 patients participated. The average perception and satisfaction regarding clinical trials among patients on a 5 point scale was 3.99±0.45 and 4.09±0.55 respectively. There was a significant difference in the correlation among participants' perception and their satisfaction (r =.67, p<.001). Regression analysis revealed that satisfaction was explained by, perception of clinical trials (β =.67, p<.001), participation period 30~59 days (β =.21, p=.009), and participation period over 60 days (β=.20, p=.013). These variables explained 48.7% of the variance of clinical trial satisfaction.

Conclusion

The results of this study suggest that changes in perceptions of clinical trials are needed to improve satisfaction of anticancer drug clinical trials. This can be used as a basis for improving the quality of clinical trials and education programs for cancer patients participating in clinical trials.

Keywords: Neoplasms, Clinical trial, Perception, Personal satisfaction

Figures and Tables

Table 1

Differences in Perception and Satisfaction of Participants according to General and Clinical Characteristics (N=106)

^*Glottic cancer, thymic cancer, buccal cancer, peritoneal cancer; ^†Acute myeloid leukemia M2, small cell lung cancer extensive disease.

Table 2

Differences in Perception and Satisfaction of Participants according to Clinical Trial related Characteristics (N=106)

Table 3

Levels of Perception and Satisfaction about Clinical Trials of Anticancer Drugs (N=106)

Table 4

Correlation among Participants'Perception and Satis-faction about Clinical Trials of Anticancer Drugs (N=106)

Table 5

Influencing Factors on Satisfaction about Clinical Trials of Anticancer Drugs (N=106)

VIF= Variance inflation factor; Participation period <30= 0.

Notes

The article is a revision of the first author's mater's thesis from University of Ulsan.

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ORCID iDs

Ju Kyung Jeon
https://orcid.org/0000-0002-9404-6012

Jeong Hye Kim
https://orcid.org/0000-0001-5384-706X

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