Abstract
Constipation is a common functional problem of the digestive system and may occur secondary to diet, drugs, endocrine diseases, metabolic diseases, neurological diseases, psychiatric disorders, or gastrointestinal obstruction. When there is no secondary cause, constipation is diagnosed as functional constipation. The first steps that should be taken to relieve symptoms are diet and lifestyle modifications, and if unsuccessful, laxative therapy should be initiated. If a patient does not respond to laxative therapy, diagnostic anorectal physiological tests are performed, though they are not routinely recommended. However, these tests may be considered earlier in patients strongly suspected to have a defecatory disorder. The revised guideline on the diagnosis and treatment of chronic constipation will undoubtedly aid the individualized management of chronic constipation in clinical practice.
Figures and Tables
References
1. Shin JE, Jung HK, Lee TH, et al. Guidelines for the diagnosis and treatment of chronic functional constipation in Korea, 2015 revised edition. J Neurogastroenterol Motil. 2016; 22:383–411.
3. Shin JE. Pharmacological treatment of chronic constipation: focused on oral laxatives. J Korean Med Assoc. 2018; 61:57–61.
4. Lindberg G, Hamid SS, Malfertheiner P, et al. World gastroenterology organisation global guideline: constipation--a global perspective. J Clin Gastroenterol. 2011; 45:483–487.
5. Lewis SJ, Heaton KW. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol. 1997; 32:920–924.
6. Saad RJ, Rao SS, Koch KL, et al. Do stool form and frequency correlate with whole-gut and colonic transit? Results from a multicenter study in constipated individuals and healthy controls. Am J Gastroenterol. 2010; 105:403–411.
7. Talley NJ. How to do and interpret a rectal examination in gastroenterology. Am J Gastroenterol. 2008; 103:820–822.
8. Tantiphlachiva K, Rao P, Attaluri A, Rao SS. Digital rectal examination is a useful tool for identifying patients with dyssynergia. Clin Gastroenterol Hepatol. 2010; 8:955–960.
9. American Gastroenterological Association. Bharucha AE, Dorn SD, Lembo A, Pressman A. American gastroenterological association medical position statement on constipation. Gastroenterology. 2013; 144:211–217.
10. Paré P, Bridges R, Champion MC, et al. Recommendations on chronic constipation (including constipation associated with irritable bowel syndrome) treatment. Can J Gastroenterol. 2007; 21:Suppl B. 3B–22B.
11. Tack J, Müller-Lissner S, Stanghellini V, et al. Diagnosis and treatment of chronic constipation--a European perspective. Neurogastroenterol Motil. 2011; 23:697–710.
12. Rao SS. Constipation: evaluation and treatment of colonic and anorectal motility disorders. Gastroenterol Clin North Am. 2007; 36:687–711. x
13. Bove A, Pucciani F, Bellini M, et al. Consensus statement AIGO/SICCR: diagnosis and treatment of chronic constipation and obstructed defecation (part I: diagnosis). World J Gastroenterol. 2012; 18:1555–1564.
14. Bharucha AE, Pemberton JH, Locke GR 3rd. American gastroenterological association technical review on constipation. Gastroenterology. 2013; 144:218–238.
16. Wald A. Is chronic use of stimulant laxatives harmful to the colon? J Clin Gastroenterol. 2003; 36:386–389.
17. Bove A, Bellini M, Battaglia E, et al. Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation (part II: treatment). World J Gastroenterol. 2012; 18:4994–5013.
18. Shin JE, Hong KS, Jung KW, et al. Guidelines for the use of laxatives - which laxatives, when? Korean J Med. 2015; 88:22–26.
19. Mendoza J, Legido J, Rubio S, Gisbert JP. Systematic review: the adverse effects of sodium phosphate enema. Aliment Pharmacol Ther. 2007; 26:9–20.
20. Paran H, Butnaru G, Neufeld D, Magen A, Freund U. Enema-induced perforation of the rectum in chronically constipated patients. Dis Colon Rectum. 1999; 42:1609–1612.
21. Rao SS, Valestin J, Brown CK, Zimmerman B, Schulze K. Long-term efficacy of biofeedback therapy for dyssynergic defecation: randomized controlled trial. Am J Gastroenterol. 2010; 105:890–896.
22. Lee HJ, Boo SJ, Jung KW, et al. Long-term efficacy of biofeedback therapy in patients with dyssynergic defecation: results of a median 44 months follow-up. Neurogastroenterol Motil. 2015; 27:787–795.