Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review

Yeonji Jang; Namju Kim; Sang In Khwarg; Ho Kyung Choung

doi:10.3341/jkos.2019.60.2.103

Journal List > J Korean Ophthalmol Soc > v.60(2) > 1116287

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Jang, Kim, Khwarg, and Choung: Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review

Original Article

Journal of the Korean Ophthalmological Society 2019; 60(2): 103-108.

Published online: 15 February 2019

DOI: https://doi.org/10.3341/jkos.2019.60.2.103

Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review

Yeonji Jang, MD¹, Namju Kim, MD², Sang In Khwarg, MD¹, Ho Kyung Choung, MD³

¹Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.

²Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.

³Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.

Address reprint requests to Namju Kim, MD. Department of Ophthalmology, Seoul National University Bundang Hospital, #82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 13620, Korea. Tel: 82-31-787-7376, Fax: 82-31-787-4057, resourceful@hanmail.net

Received 2 August 2018 Revised 3 October 2018 Accepted 19 January 2019

The Korean Ophthalmological Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

We report 9 cases of molluscum contagiosum of the eyelid margin and a literature review.

Methods

A retrospective, observational case series of 9 patients who were diagnosed with molluscum contagiosum of the eyelid margin.

Results

Subjects included 8 female patients and 1 male patient with an average age of 6.1 years. The patients were all healthy without any underlying disease, and their blood analyses and chest X-rays excluded any infectious disease or immune-related problem. Each patient had 1–6 skin lesions. Hematoxylin and eosin staining revealed lobular hyperplasia of the squamous epithelium, which invaded into the underlying dermis. Staining also revealed inclusion bodies in the cytoplasm of keratinocytes above the basal layer. All patients were maintained without complications or recurrence after surgical treatment.

Conclusions

Molluscum contagiosum on the eyelid margin differs from those on other body parts. Subjects had fewer lesions and lesion shapes were atypical. Early surgical treatment may be necessary because molluscum contagiosum can lead to ocular complications such as conjunctivitis.

Keywords: Eyelid diseases, Histologic diagnosis, Molluscum contagiosum

Figures and Tables

Figure 1

Clinical photographs and histopathologic findings of patients. (A, B) Case 1. (C, D) Case 2. (E, F) Case 3. (G, H) Case 4. All the patients had small, flesh-colored mass on the eyelid margin (A, C, E, G), and pathologic examination revealed multiple lobular hyperplasia of squamous epithelium invading into the dermis with large, homogenous inclusion bodies in the keratinocytes displacing the cell nucleus peripherally (arrows in H) (hematoxylin and eosin stain, ×40 [B, D, F], ×100 [H]).

Table 1

Demographic characteristics of the patients in molluscum contagiosum of eyelid margin

F= female; M = male; RUL = right upper lid; RLL = right lower lid; LUL = left upper lid; LLL = left lower lid.

Notes

^{Conflicts of Interest} The authors have no conflicts to disclose.

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