Journal List > J Korean Ophthalmol Soc > v.60(2) > 1116287

Jang, Kim, Khwarg, and Choung: Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review

Abstract

Purpose

We report 9 cases of molluscum contagiosum of the eyelid margin and a literature review.

Methods

A retrospective, observational case series of 9 patients who were diagnosed with molluscum contagiosum of the eyelid margin.

Results

Subjects included 8 female patients and 1 male patient with an average age of 6.1 years. The patients were all healthy without any underlying disease, and their blood analyses and chest X-rays excluded any infectious disease or immune-related problem. Each patient had 1–6 skin lesions. Hematoxylin and eosin staining revealed lobular hyperplasia of the squamous epithelium, which invaded into the underlying dermis. Staining also revealed inclusion bodies in the cytoplasm of keratinocytes above the basal layer. All patients were maintained without complications or recurrence after surgical treatment.

Conclusions

Molluscum contagiosum on the eyelid margin differs from those on other body parts. Subjects had fewer lesions and lesion shapes were atypical. Early surgical treatment may be necessary because molluscum contagiosum can lead to ocular complications such as conjunctivitis.

Figures and Tables

Figure 1

Clinical photographs and histopathologic findings of patients. (A, B) Case 1. (C, D) Case 2. (E, F) Case 3. (G, H) Case 4. All the patients had small, flesh-colored mass on the eyelid margin (A, C, E, G), and pathologic examination revealed multiple lobular hyperplasia of squamous epithelium invading into the dermis with large, homogenous inclusion bodies in the keratinocytes displacing the cell nucleus peripherally (arrows in H) (hematoxylin and eosin stain, ×40 [B, D, F], ×100 [H]).

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Table 1

Demographic characteristics of the patients in molluscum contagiosum of eyelid margin

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F= female; M = male; RUL = right upper lid; RLL = right lower lid; LUL = left upper lid; LLL = left lower lid.

Notes

Conflicts of Interest The authors have no conflicts to disclose.

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