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Lee, Kim, Lee, Kim, Seo, Hyun, Kang, Lee, and Hwang: Successful surgical correction of anal atresia in a transgenic cloned piglet
Brief Communication

Journal of Veterinary Science 2005; 6(3): 243-245.

Published online: 11 February 2019

DOI: https://doi.org/10.4142/jvs.2005.6.3.243

Successful surgical correction of anal atresia in a transgenic cloned piglet

Gab Sang Lee, Hye Soo Kim, So Hyun Lee, Dae Yong Kim, Kang Moon Seo, Sang Hwan Hyun, Sung Keun Kang, Byeong Chun Lee, Woo Suk Hwang

Department of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.

Department of Pathology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.

Department of Surgery, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.

School of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Korea.

Xenotransplantation Research Center, Seoul National University Hospital, Seoul 110-744, Korea.

Department of Veterinary Biotechnology, College of Veterinary Medicine, Chungbuk National University, Cheongju 361-763, Korea.

bclee@snu.ac.kr

Copyright © 2005 The Korean Society of Veterinary Science

Abstract

Inbred strains of pig become indispensable for a wide range of biological studies. In biomedical science, it is generally accepted that somatic cell nuclear transfer(SCNT)technology with inbreed strain of pig is essential for xenotransplantation. In this study, we observed the anal atresia in a cloned pig which was derived from fetal fibroblast of inbreed miniature pig. A presumptive anal site of the cloned pig was excised and the rectum was sutured to apposed skin for treatment. This cloned piglet seemed to be normal with healthy status after surgery. This report can be useful for the treatment of anal atresia of cloned piglets.

Keywords: anal atresia, cloned pig, miniature pig, nuclear transfer, transgenic pig

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