Peripheral nerve entrapment syndrome has gained increasing attention and acceptance as a significant cause of peripheral neuropathy since carpal tunnel syndrome was first reported in 1854. 102 patients, who were admitted to Severance hospital during the period of from January 1972 to December 1989 with the complaint of neuropathy in the upper extermity without direct trauma, were analysed for clinical manifestations and the following results were obtained: l. Among 102 patients, 72(69%) were female and 32(31%) were male. 2. The syndrome occurred on the right upper extremity in 41 patients, on the left in 31 patients and on both extremities in 30 patients. 3. The average duration of disease was 17.2 months. 4. Median nerve was involved in 54 cases(52.9%), ulnar nerve in 41 cases(40.2%) and radial nerve in 7 cases(6.9%). 5. Paresthesia(60.8%) was the most common symptom followed by numbenss(52.9%), weakness (39.2%) and pain(14.7%). Atrophy occurred in 63 cases(61.8%) while 46 cases(45.1%) were positive for Tinel sign. 6. Denervation potential was seen in 94 cases among 100 cases which did electromyography. 86 cases(95.5%) showed abnormal findings among 93 cases which did conduction study. 7.95 cases(93.1%) received surgical treatment while 7 cases(6.9%) received conservative treatment. 8. The average follow-up duration was 17.2 months(12-48 months). Symptoms of peripheral nerve entrapment syndrome were relieved in 98 cases.