Three-phase skeletal scintigraphy, consisting of a radionuclide angiogram, blood pool image and 3 hours delayed image was performed on 34 patients with suspected osteomyelitis. First, this procedure was evaluated by interpreting only the delayed images, next the combination of blood pool image and delayed images, and finally the three-phase study. The sensitivity for diagnosing osteomyelitis using delayed image alone was high (10/11 = 90.0 %), and was unchanged by the addition of the blood pool image and radionuclide angiography. But the specificity for osteomyelitis with delayed images was increased by addition of the blood pool image from 69.57% (16/23) to 100% (23/23), thus the false positive rate was decreased from 41.18% (7/17) to 0% (0/10) Three-phase-scintigraphy, especially radionuclide angiogram is most helpful for accurately detecting focal blood flow abnormality, thus it do increase the sensitivity of scintigraphy for patient with cellulitis or septic arthritis.