Osteosarcoma in a malignant bone tumor usually located in the metaphysis close to the knee in the most cases. Primary osteogenic sarcoma of the cervical spine is extremely rare. The patient had relatively prolonged survival after partial excision of vertebral body combined with decompressive laminectomy, radiotherapy, and chemotherapy. Although rare, osteosarcoma of the spine can usually be suspected on roentgenograms, and then most aggressive therapy is justified. To our knowledge, there is no report on primary osteosarcoma of the cervical spine in Korea. The authors report a case of primary osteosarcoma of cervical spine with review of literatures.